Browse by UCL people
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Number of items: 54.
Article
Aartsma-Rus, A;
Morgan, J;
Lonkar, P;
Neubert, H;
Owens, J;
Binks, M;
Montolio, M;
... Arechavala-Gomeza, V; + view all
(2019)
Report of a TREAT-NMD/World Duchenne Organisation Meeting on Dystrophin Quantification Methodology.
Journal of Neuromuscular Diseases
, 6
(1)
pp. 147-159.
10.3233/JND-180357.
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Alameddine, HS;
Morgan, JE;
(2016)
Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Inflammation and Fibrosis of Skeletal Muscles.
Journal of Neuromuscular Diseases
, 3
(4)
pp. 455-473.
10.3233/JND-160183.
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Anthony, K;
Arechavala-Gomeza, V;
Ricotti, V;
Torelli, S;
Feng, L;
Janghra, N;
Tasca, G;
... Muntoni, F; + view all
(2014)
Biochemical characterization of patients with in-frame or out-of-frame DMD deletions pertinent to exon 44 or 45 skipping.
JAMA Neurology
, 71
(1)
32 - 40.
10.1001/jamaneurol.2013.4908.
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Anthony, K;
Arechavala-Gomeza, V;
Taylor, LE;
Vulin, A;
Kaminoh, Y;
Torelli, S;
Feng, L;
... Muntoni, F; + view all
(2014)
Dystrophin quantification: Biological and translational research implications.
Neurology
, 83
(22)
2062 - 2069.
10.1212/WNL.0000000000001025.
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Arechavala-Gomeza, V;
Anthony, K;
Morgan, J;
Muntoni, F;
(2012)
Antisense Oligonucleotide-Mediated Exon Skipping for Duchenne Muscular Dystrophy: Progress and Challenges.
Current Gene Therapy
, 12
(3)
pp. 152-160.
10.2174/156652312800840621.
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Arechavala-Gomeza, V;
Feng, L;
Morgan, JE;
Muntoni, F;
(2012)
Correspondence: Measuring dystrophin-faster is not necessarily better.
[Letter].
Nature Reviews Neurology
, 8
(8)
469 -470.
10.1038/nrneurol.2012.15-c1.
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Arechavala-Gomeza, V;
Graham, IR;
Popplewell, LJ;
Adams, AM;
Aartsma-Rus, A;
Kinali, M;
Morgan, JE;
... Muntoni, F; + view all
(2007)
Comparative analysis of antisense oligonucleotide sequences for targeted skipping of Exon 51 during dystrophin Pre-mRNA splicing in human muscle.
Human Gene Therapy
, 18
(9)
798 - 810.
10.1089/hum.2006.061.
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Arechavala-Gomeza, V;
Kinali, M;
Feng, L;
Brown, SC;
Sewry, C;
Morgan, JE;
Muntoni, F;
(2010)
Immunohistological intensity measurements as a tool to assess sarcolemma-associated protein expression.
NEUROPATH APPL NEURO
, 36
(4)
265 - 274.
10.1111/j.1365-2990.2009.01056.x.
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Arechavala-Gomeza, V;
Kinali, M;
Feng, L;
Guglieri, M;
Edge, G;
Main, M;
Hunt, D;
... Muntoni, F; + view all
(2010)
Revertant fibres and dystrophin traces in Duchenne muscular dystrophy: Implication for clinical trials.
Neuromuscular Disorders
, 20
(5)
295 - 301.
10.1016/j.nmd.2010.03.007.
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Betts, CA;
Jagannath, A;
van Westering, TLE;
Bowerman, M;
Banerjee, S;
Meng, J;
Falzarano, MS;
... Wood, MJA; + view all
(2021)
Dystrophin involvement in peripheral circadian SRF signalling.
Life Science Alliance
, 4
(10)
, Article e202101014. 10.26508/lsa.202101014.
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Boldrin, L;
Morgan, JE;
(2013)
Grafting of a single donor myofibre promotes hypertrophy in dystrophic mouse muscle.
PLoS One
, 8
(1)
, Article e54599. 10.1371/journal.pone.0054599.
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Boldrin, L;
Morgan, JE;
(2012)
Human satellite cells: identification on human muscle fibres.
PLoS Curr
, 3
10.1371/currents.RRN1294.
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Boldrin, L;
Ross, JA;
Whitmore, C;
Doreste, B;
Beaver, C;
Eddaoudi, A;
Pearce, DJ;
(2017)
The effect of calorie restriction on mouse skeletal muscle is sex, strain and time-dependent.
Science Reports
, 7
(1)
, Article 5160. 10.1038/s41598-017-04896-y.
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Boldrin, L;
Zammit, PS;
Morgan, JE;
(2015)
Satellite cells derived from the mdx murine model of Duchenne muscular dystrophy retain their muscle regenerative capacity.
Stem Cell Research
, 14
(1)
pp. 20-29.
10.1016/j.scr.2014.10.007.
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Briggs, D;
Morgan, JE;
(2013)
Recent progress in satellite cell/myoblast engraftment – relevance for therapy.
FEBS Journal
, 280
(17)
pp. 4281-4293.
10.1111/febs.12273.
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Catapano, F;
Domingos, J;
Perry, M;
Ricotti, V;
Phillips, L;
Servais, L;
Seferian, A;
... Muntoni, F; + view all
(2018)
Downregulation of miRNA-29, -23 and -21 in urine of Duchenne muscular dystrophy patients.
Epigenomics
, 10
(7)
pp. 875-889.
10.2217/epi-2018-0022.
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Catapano, F;
Zaharieva, I;
Scoto, M;
Marrosu, E;
Morgan, J;
Muntoni, F;
Zhou, H;
(2016)
Altered Levels of MicroRNA-9,-206, and-132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy.
Molecular Therapy-Nucleic Acids
, 5
, Article e331. 10.1038/mtna.2016.47.
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Coenen-Stass, AM;
Betts, CA;
Lee, YF;
Mäger, I;
Turunen, MP;
El Andaloussi, S;
Morgan, JE;
... Roberts, TC; + view all
(2016)
Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation.
Human Molecular Genetics
, 25
(18)
pp. 3960-3974.
10.1093/hmg/ddw237.
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Collins, CA;
Gnocchi, VF;
White, RB;
Boldrin, L;
Perez-Ruiz, A;
Relaix, F;
Morgan, JE;
(2009)
Integrated Functions of Pax3 and Pax7 in the Regulation of Proliferation, Cell Size and Myogenic Differentiation.
PLOS ONE
, 4
(2)
, Article e4475. 10.1371/journal.pone.0004475.
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Counsell, JR;
Asgarian, Z;
Meng, J;
Ferrer, V;
Vink, CA;
Howe, SJ;
Waddington, SN;
... Danos, O; + view all
(2017)
Lentiviral vectors can be used for full-length dystrophin gene therapy.
Scientific Reports
, 7
, Article 44775. 10.1038/srep44775.
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Doisy, Mathilde;
Vacca, Ophélie;
Fergus, Claire;
Gileadi, Talia;
Verhaeg, Minou;
Saoudi, Amel;
Tensorer, Thomas;
... Goyenvalle, Aurélie; + view all
(2023)
Networking to Optimize Dmd exon 53 Skipping in the Brain of mdx52 Mouse Model.
Biomedicines
, 11
(12)
, Article 3243. 10.3390/biomedicines11123243.
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Doreste, B;
Torelli, S;
Morgan, J;
(2020)
Irradiation dependent inflammatory response may enhance satellite cell engraftment.
Scientific Reports
, 10
, Article 11119. 10.1038/s41598-020-68098-9.
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Frank, DE;
Schnell, FJ;
Akana, C;
El-Husayni, SH;
Desjardins, CA;
Morgan, J;
Charleston, JS;
... SKIP-NMD Study Group; + view all
(2020)
Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy.
Neurology
10.1212/WNL.0000000000009233.
(In press).
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Janghra, N;
Morgan, JE;
Sewry, CA;
Wilson, FX;
Davies, KE;
Muntoni, F;
Tinsley, J;
(2016)
Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.
PLoS One
, 11
(3)
, Article e0150818. 10.1371/journal.pone.0150818.
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Mariot, V;
Le Guiner, C;
Barthelemy, I;
Montus, M;
Blot, S;
Torelli, S;
Morgan, J;
... Dumonceaux, J; + view all
(2020)
Myostatin is a quantifiable biomarker for monitoring pharmaco-gene therapy in Duchenne Muscular Dystrophy.
Molecular Therapy - Methods and Clinical Development
, 18
pp. 415-421.
10.1016/j.omtm.2020.06.016.
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Meng, Jinhong;
Moore, Marc;
Counsell, John;
Muntoni, Francesco;
Popplewell, Linda;
Morgan, Jennifer;
(2022)
Optimized lentiviral vector for restoration of full-length dystrophin via a cell-mediated approach in a mouse model of Duchenne muscular dystrophy.
Molecular Therapy: Methods & Clinical Development
10.1016/j.omtm.2022.04.015.
(In press).
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Meng, J;
Counsell, J;
Morgan, JE;
(2020)
Effects of Mini-Dystrophin on Dystrophin-Deficient, Human Skeletal Muscle-Derived Cells.
International Journal of Molecular Sciences
, 21
(19)
, Article 7168. 10.3390/ijms21197168.
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Meng, J;
Counsell, JR;
Reza, M;
Laval, SH;
Danos, O;
Thrasher, A;
Lochmüller, H;
... Morgan, JE; + view all
(2016)
Autologous skeletal muscle derived cells expressing a novel functional dystrophin provide a potential therapy for Duchenne Muscular Dystrophy.
Scientific Reports
, 6
, Article 19750. 10.1038/srep19750.
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Meng, J;
Muntoni, F;
Morgan, J;
(2018)
CD133+cells derived from skeletal muscles of Duchenne muscular dystrophy patients have a compromised myogenic and muscle regenerative capability.
Stem Cell Research
, 30
pp. 43-52.
10.1016/j.scr.2018.05.004.
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Meng, J;
Sweeney, N;
Doreste, B;
Muntoni, F;
McClure, M;
Morgan, J;
(2020)
Restoration of Functional Full-Length Dystrophin After Intramuscular Transplantation of Foamy Virus-Transduced Myoblasts.
Human Gene Therapy
, 31
(3-4)
10.1089/hum.2019.224.
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Meng, JH;
Adkin, CF;
Xu, SW;
Muntoni, F;
Morgan, JE;
(2011)
Contribution of Human Muscle-Derived Cells to Skeletal Muscle Regeneration in Dystrophic Host Mice.
PLOS ONE
, 6
(3)
, Article e17454. 10.1371/journal.pone.0017454.
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Morgan, J;
Muntoni, F;
(2021)
Changes in Myonuclear Number During Postnatal Growth – Implications for AAV Gene Therapy for Muscular Dystrophy.
Journal of Neuromuscular Diseases
, 8
(s2)
S317-S324.
10.3233/JND-210683.
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Morgan, J;
Butler-Browne, G;
Muntoni, F;
Patel, K;
Skeletal Muscle Stem Cells Involvement in Pathology Study Group;
(2019)
240th ENMC workshop: The involvement of skeletal muscle stem cells in the pathology of muscular dystrophies 25-27 January 2019, Hoofddorp, The Netherlands.
Neuromuscular Disorders
, 29
(9)
pp. 704-715.
10.1016/j.nmd.2019.07.003.
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Morgan, J;
Partridge, T;
(2020)
Skeletal muscle in health and disease.
Disease Models & Mechanisms
, 13
(2)
, Article dmm042192. 10.1242/dmm.042192.
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Morgan, JE;
Prola, A;
Mariot, V;
Pini, V;
Meng, J;
Hourde, C;
Dumonceaux, J;
... Bencze, M; + view all
(2018)
Publisher Correction: Necroptosis Mediates Myofibre Death in Dystrophin-deficient Mice.
[Corrigendum].
Nature Communications
, 9
(1)
, Article 4107. 10.1038/s41467-018-06636-w.
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Morgan, JE;
Prola, A;
Mariot, V;
Pini, V;
Meng, J;
Hourde, C;
Dumonceaux, J;
... Bencze, M; + view all
(2018)
Necroptosis mediates myofibre death in dystrophin-deficient mice.
Nature Communications
, 9
, Article 3655. 10.1038/s41467-018-06057-9.
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Muses, S;
Morgan, JE;
Wells, DJ;
(2012)
Restoration of dystrophin expression using the Sleeping Beauty transposon.
PLoS Currents Muscular Dystrophy
, 3
, Article RRN1296. 10.1371/currents.RRN1296.
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Muses, S;
Morgan, JE;
Wells, DJ;
(2011)
A New Extensively Characterised Conditionally Immortal Muscle Cell-Line for Investigating Therapeutic Strategies in Muscular Dystrophies.
PLOS ONE
, 6
(9)
, Article e24826. 10.1371/journal.pone.0024826.
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Neal, A;
Boldrin, L;
Morgan, JE;
(2012)
The satellite cell in male and female, developing and adult mouse muscle: distinct stem cells for growth and regeneration.
PLoS One
, 7
(5)
, Article e37950. 10.1371/journal.pone.0037950.
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O'Neill, HC;
Pini, V;
Muntoni, F;
Morgan, J;
(2017)
Genome Editing and Muscle Stem Cells as a Therapeutic Tool for Muscular Dystrophies.
Current Stem Cell Reports
, 3
(2)
pp. 137-148.
10.1007/s40778-017-0076-6.
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Reza, M;
Cox, D;
Phillips, L;
Johnson, D;
Manoharan, V;
Grieves, M;
Davis, B;
... Lochmüller, H; + view all
(2017)
MRC Centre Neuromuscular Biobank (Newcastle and London): Supporting and facilitating rare and neuromuscular disease research worldwide.
Neuromuscular Disorders
, 27
(11)
pp. 1054-1064.
10.1016/j.nmd.2017.07.001.
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Ross, JA;
Tasfaout, H;
Levy, Y;
Morgan, J;
Cowling, BS;
Laporte, J;
Zanoteli, E;
... Ochala, J; + view all
(2020)
rAAV-related therapy fully rescues myonuclear and myofilament function in X-linked myotubular myopathy.
Acta Neuropathologica Communications
, 8
(1)
, Article 167. 10.1186/s40478-020-01048-8.
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Rossi, Rachele;
Torelli, Silvia;
Ala, Pierpaolo;
Weston, William;
Morgan, Jennifer;
Malhotra, Jyoti;
Muntoni, Francesco;
(2023)
MyoD-induced reprogramming of human fibroblasts and urinary stem cells in vitro: protocols and their applications.
Frontiers in Physiology
, 14
, Article 1145047. 10.3389/fphys.2023.1145047.
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Rozkalne, A;
Adkin, C;
Meng, J;
Lapan, A;
Morgan, JE;
Gussoni, E;
(2014)
Mouse Regenerating Myofibers Detected as False-Positive Donor Myofibers with Anti-Human Spectrin.
Human Gene Therapy
, 25
(1)
73 - 81.
10.1089/hum.2013.126.
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Sardone, V;
Ellis, M;
Torelli, S;
Feng, L;
Chambers, D;
Eastwood, D;
Sewry, C;
... Muntoni, F; + view all
(2018)
A novel high-throughput immunofluorescence analysis method for quantifying dystrophin intensity in entire transverse sections of Duchenne muscular dystrophy muscle biopsy samples.
PLoS One
, 13
(3)
, Article e0194540. 10.1371/journal.pone.0194540.
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Scaglioni, D;
Catapano, F;
Ellis, M;
Torelli, S;
Chambers, D;
Feng, L;
Beck, M;
... Muntoni, F; + view all
(2021)
The administration of antisense oligonucleotide golodirsen reduces pathological regeneration in patients with Duchenne muscular dystrophy.
Acta Neuropathologica Communications
, 9
(1)
, Article 7. 10.1186/s40478-020-01106-1.
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Scaglioni, D;
Ellis, M;
Catapano, F;
Torelli, S;
Chambers, D;
Feng, L;
Sewry, C;
... Phadke, R; + view all
(2020)
A high–throughput digital script for multiplexed immunofluorescent analysis and quantification of sarcolemmal and sarcomeric proteins in muscular dystrophies.
Acta Neuropathologica Communications
, 8
, Article 53. 10.1186/s40478-020-00918-5.
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Sintusek, P;
Catapano, F;
Angkathunkayul, N;
Marrosu, E;
Parson, SH;
Morgan, JE;
Muntoni, F;
(2016)
Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment.
PLOS One
, 11
(5)
, Article e0155032. 10.1371/journal.pone.0155032.
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Spicer, C;
Lu, C-H;
Catapano, F;
Scoto, M;
Zaharieva, I;
Malaspina, A;
Morgan, JE;
... Zhou, H; + view all
(2021)
The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy.
Annals of Clinical and Translational Neurology
10.1002/acn3.51336.
(In press).
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Sweeney, NP;
Meng, J;
Patterson, H;
Morgan, JE;
McClure, M;
(2017)
Delivery of large transgene cassettes by foamy virus vector.
Scientific Reports
, 7
(1)
, Article 8085. 10.1038/s41598-017-08312-3.
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Torelli, S;
Scaglioni, D;
Sardone, V;
Ellis, MJ;
Domingos, J;
Jones, A;
Feng, L;
... Muntoni, F; + view all
(2021)
High-Throughput Digital Image Analysis Reveals Distinct Patterns of Dystrophin Expression in Dystrophinopathy Patients.
Journal of Neuropathology & Experimental Neurology
, Article nlab088. 10.1093/jnen/nlab088.
(In press).
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White, MJ;
Beaver, CM;
Goodier, MR;
Bottomley, C;
Nielsen, CM;
Wolf, A-SFM;
Boldrin, L;
... Riley, EM; + view all
(2017)
Calorie Restriction Attenuates Terminal Differentiation of Immune Cells.
Frontiers in Immunology
, 7
, Article 667. 10.3389/fimmu.2016.00667.
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Zaharieva, IT;
Calissano, M;
Scoto, M;
Preston, M;
Cirak, S;
Feng, L;
Collins, J;
... Muntoni, F; + view all
(2013)
Dystromirs as serum biomarkers for monitoring the disease severity in duchenne muscular dystrophy.
PLoS One
, 8
(11)
, Article e80263. 10.1371/journal.pone.0080263.
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Zhou, H;
Meng, J;
Malerba, A;
Catapano, F;
Sintusek, P;
Jarmin, S;
Feng, L;
... Muntoni, F; + view all
(2020)
Myostatin inhibition in combination with antisense oligonucleotide therapy improves outcomes in spinal muscular atrophy.
Journal of Cachexia, Sarcopenia and Muscle
10.1002/jcsm.12542.
(In press).
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