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Number of items: 27.
Article
Canetti, D;
Nocerino, P;
Rendell, NB;
Botcher, N;
Gilbertson, JA;
Blanco, A;
Rowczenio, D;
... Taylor, GW; + view all
(2021)
Clinical ApoA-IV amyloid is associated with fibrillogenic signal sequence.
The Journal of Pathology
, 255
(3)
pp. 311-318.
10.1002/path.5770.
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Canetti, D;
Brambilla, F;
Rendell, NB;
Nocerino, P;
Gilbertson, JA;
Di Silvestre, D;
Bergamaschi, A;
... Taylor, GW; + view all
(2021)
Clinical Amyloid Typing by Proteomics: Performance Evaluation and Data Sharing Between Two Centres.
Molecules
, 26
(7)
, Article 1913. 10.3390/molecules26071913.
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Canetti, D;
Rendell, NB;
Di Vagno, L;
Gilbertson, JA;
Rowczenio, D;
Rezk, T;
Gillmore, JD;
... Taylor, GW; + view all
(2017)
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue.
Amyloid
, 27
(4)
pp. 229-237.
10.1080/13506129.2017.1385452.
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Canetti, D;
Rendell, NB;
Gilbertson, JA;
Botcher, N;
Nocerino, P;
Blanco, A;
Di Vagno, L;
... Taylor, GW; + view all
(2020)
Diagnostic amyloid proteomics: experience of the UK National Amyloidosis Centre.
Clinical Chemistry and Laboratory Medicine
, 58
(6)
pp. 948-957.
10.1515/cclm-2019-1007.
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Cantarutti, C;
Mimmi, MC;
Verona, G;
Mandaliti, W;
Taylor, GW;
Mangione, PP;
Giorgetti, S;
... Corazza, A; + view all
(2022)
Calcium Binds to Transthyretin with Low Affinity.
Biomolecules
, 12
(8)
, Article 1066. 10.3390/biom12081066.
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Corazza, A;
Verona, G;
Waudby, CA;
Mangione, PP;
Bingham, RP;
Uings, I;
Canetti, D;
... Bellotti, V; + view all
(2019)
Binding of monovalent and bivalent ligands by transthyretin causes different short and long distance conformational changes.
Journal of Medicinal Chemistry
, 62
(17)
pp. 8274-8283.
10.1021/acs.jmedchem.9b01037.
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Ellmerich, S;
Taylor, GW;
Richardson, CD;
Minett, T;
Schmidt, AF;
Brayne, C;
Matthews, FE;
... Cognitive Function and Ageing Study; + view all
(2021)
Dementia in the older population is associated with neocortex content of serum amyloid P component.
Brain Communications
, 3
(4)
, Article fcab225. 10.1093/braincomms/fcab225.
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Keegan, R;
Waterman, DG;
Hopper, DJ;
Coates, L;
Taylor, G;
Guo, J;
Coker, AR;
... Cooper, JB; + view all
(2016)
The 1.1 angstrom resolution structure of a periplasmic phosphate-binding protein from Stenotrophomonas maltophilia: a crystallization contaminant identified by molecular replacement using the entire Protein Data Bank.
Acta Crystallographica Section D: Structural Biology
, D72
(8)
pp. 933-943.
10.1107/S2059798316010433.
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Kern, CC;
Townsend, S;
Salzmann, A;
Rendell, NB;
Taylor, GW;
Comisel, RM;
Foukas, LC;
... Gems, D; + view all
(2021)
C. elegans feed yolk to their young in a form of primitive lactation.
Nature Communications
, 12
(1)
, Article 5801. 10.1038/s41467-021-25821-y.
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Mangione, PP;
Verona, G;
Cantarutti, C;
Nocerino, P;
Mimmi, MC;
Swain, CJ;
Canetti, D;
... Corazza, A; + view all
(2025)
Design and Mechanistic Analysis of a Potent Bivalent Inhibitor of Transthyretin Amyloid Fibrillogenesis.
Journal of Medicinal Chemistry
10.1021/acs.jmedchem.5c00430.
(In press).
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Mangione, PP;
Deroo, S;
Ellmerich, S;
Bellotti, V;
Kolstoe, S;
Wood, SP;
Robinson, CV;
... Taylor, GW; + view all
(2015)
Bifunctional crosslinking ligands for transthyretin.
Open Biology
, 5
(9)
, Article 150105. 10.1098/rsob.150105.
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Mangione, PP;
Esposito, G;
Relini, A;
Raimondi, S;
Porcari, R;
Giorgetti, S;
Corazza, A;
... Bellotti, V; + view all
(2013)
Structure, Folding Dynamics, and Amyloidogenesis of D76N β2-Microglobulin: ROLES OF SHEAR FLOW, HYDROPHOBIC SURFACES, AND α-CRYSTALLIN.
Journal of Biological Chemistry
, 288
(43)
30917- 30930.
10.1074/jbc.M113.498857.
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Mangione, PP;
Mazza, G;
Gilbertson, JA;
Rendell, NB;
Canetti, D;
Giorgetti, S;
Frenguelli, L;
... Bellotti, V; + view all
(2017)
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies.
Journal of Proteomics
, 165
pp. 113-118.
10.1016/j.jprot.2017.06.016.
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Mangione, PP;
Porcari, R;
Gillmore, JD;
Pucci, P;
Monti, M;
Porcari, M;
Giorgetti, S;
... Bellotti, V; + view all
(2014)
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proceedings of the National Academy of Sciences of the United States of America
, 111
(4)
pp. 1539-1544.
10.1073/pnas.1317488111.
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Mangione, PP;
Verona, G;
Corazza, A;
Marcoux, J;
Canetti, D;
Giorgetti, S;
Raimondi, S;
... Bellotti, V; + view all
(2018)
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
Journal of Biological Chemistry
, 293
(37)
pp. 14192-14199.
10.1074/jbc.RA118.003990.
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Marcoux, J;
Mangione, PP;
Porcari, R;
Degiacomi, MT;
Verona, G;
Taylor, GW;
Giorgetti, S;
... Bellotti, V; + view all
(2015)
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.
EMBO Mol Med
, 7
(10)
pp. 1337-1349.
10.15252/emmm.201505357.
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Mazza, G;
Simons, JP;
Al-Shawi, R;
Ellmerich, S;
Urbani, L;
Giorgetti, S;
Taylor, GW;
... Mangione, PP; + view all
(2015)
Amyloid persistence in decellularized liver: biochemical and histopathological characterization.
Amyloid
, 23
(1)
pp. 1-7.
10.3109/13506129.2015.1110518.
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Moura, A;
Nocerino, P;
Gilbertson, JA;
Rendell, NB;
Mangione, PP;
Verona, G;
Rowczenio, D;
... Canetti, D; + view all
(2020)
Lysozyme amyloid: evidence for the W64R variant by proteomics in the absence of the wild type protein.
[Letter].
Amyloid
10.1080/13506129.2020.1720637.
(In press).
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Pepys, MB;
Gallimore, JR;
Lloyd, J;
Li, Z;
Graham, D;
Taylor, GW;
Ellmerich, S;
... Hawkins, PN; + view all
(2012)
Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C-reactive protein, for clinical use.
Journal of Immunological Methods
, 384
(1-2)
92 - 102.
10.1016/j.jim.2012.07.013.
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Raimondi, S;
Mangione, PP;
Verona, G;
Canetti, D;
Nocerino, P;
Marchese, L;
Piccarducci, R;
... Bellotti, V; + view all
(2020)
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils.
Journal of Biological Chemistry
, 295
(33)
pp. 11379-11387.
10.1074/jbc.RA120.014026.
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Raimondi, S;
Porcari, R;
Mangione, PP;
Verona, G;
Marcoux, J;
Giorgetti, S;
Taylor, GW;
... Bellotti, V; + view all
(2017)
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.
Scientific Reports
, 7
, Article 46711. 10.1038/srep46711.
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Rezk, T;
Gilbertson, JA;
Mangione, PP;
Rowczenio, D;
Rendell, N;
Canetti, D;
Lachmann, HJ;
... Gillmore, JD; + view all
(2019)
The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis.
Journal of Pathology: Clinical Research
, 5
(3)
pp. 145-153.
10.1002/cjp2.126.
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Rezk, T;
Gilbertson, JA;
Rowczenio, D;
Bass, P;
Lachmann, HJ;
Wechalekar, AD;
Fontana, M;
... Gillmore, JD; + view all
(2018)
Diagnosis, pathogenesis and outcome in leucocyte chemotactic factor 2 (ALECT2) amyloidosis.
Nephrology Dialysis Transplantation
, 33
(2)
pp. 241-247.
10.1093/ndt/gfw375.
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Rowczenio, D;
Stensland, M;
de Souza, GA;
Strøm, EH;
Gilbertson, JA;
Taylor, G;
Rendell, N;
... Wien, TN; + view all
(2017)
Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein.
Kidney International Reports
, 2
(3)
pp. 461-469.
10.1016/j.ekir.2016.11.005.
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Slamova, I;
Adib, R;
Ellmerich, S;
Golos, MR;
Gilbertson, JA;
Botcher, N;
Canetti, D;
... Simons, JP; + view all
(2021)
Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis.
Nature Communications
, 12
(1)
, Article 7112. 10.1038/s41467-021-27416-z.
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Taylor, GW;
Gilbertson, JA;
Sayed, R;
Blanco, A;
Rendell, NB;
Rowczenio, D;
Rezk, T;
... Gillmore, JD; + view all
(2019)
Proteomic Analysis for the Diagnosis of Fibrinogen Aα-Chain Amyloidosis.
Kidney International Reports
10.1016/j.ekir.2019.04.007.
(In press).
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Verona, G;
Mangione, P;
Raimondi, S;
Giorgetti, S;
Faravelli, G;
Porcari, R;
Corazza, A;
... Bellotti, VL; + view all
(2017)
Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel.
Scientific Reports
, 7
, Article 182. 10.1038/s41598-017-00338-x.
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