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Number of items: 28.
Article
Alanazi, Abeer FR;
Haider, Shozeb;
Parkinson, Gary N;
(2024)
The use of single-molecule FRET for the characterization of Holliday junctions containing human telomeric DNA: a methodological approach for nanoscale distance, mobility, and stability measurements.
Medicinal Chemistry Research
, 33
pp. 2066-2078.
10.1007/s00044-024-03197-0.
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Alanazi, Abeer FR;
Parkinson, Gary N;
Haider, Shozeb;
(2024)
Structural Motifs at the Telomeres and Their Role in Regulatory Pathways.
Biochemistry
10.1021/acs.biochem.4c00023.
(In press).
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Burge, S;
Parkinson, GN;
Hazel, P;
Todd, AK;
Neidle, S;
(2006)
Quadruplex DNA: sequence, topology and structure.
Nucleic Acids Res
, 34
(19)
5402 - 5415.
10.1093/nar/gkl655.
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Caceres, C;
Wright, G;
Gouyette, C;
Parkinson, G;
Subirana, JA;
(2004)
A thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+/Na+ ions.
NUCLEIC ACIDS RESEARCH
, 32
(3)
1097 - 1102.
10.1093/nar/gkh269.
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Clout, A;
Buanz, A;
Pang, Y;
Tsui, W-M;
Yan, D;
Parkinson, G;
Prior, T;
... Williams, G; + view all
(2020)
Mechanistic in situ and ex situ studies of phase transformations in molecular co-crystals.
Chemistry
, 26
(64)
pp. 14645-14653.
10.1002/chem.202002267.
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Collie, GW;
Haider, SM;
Neidle, S;
Parkinson, GN;
(2010)
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex.
Nucleic Acids Res
, 38
(16)
5569 - 5580.
10.1093/nar/gkq259.
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Fratta, P;
Mizielinska, S;
Nicoll, AJ;
Zloh, M;
Fisher, EM;
Parkinson, G;
Isaacs, AM;
(2012)
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.
Scientific Reports
, 2
, Article 1016. 10.1038/srep01016.
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Gao, Chao;
Liu, Zhu;
Hou, Haitao;
Ding, Jieqin;
Chen, Xin;
Xie, Congbao;
Song, Zibing;
... Wei, Dengguo; + view all
(2020)
BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers.
Nucleic Acids Research
, 48
(20)
pp. 11259-11269.
10.1093/nar/gkaa870.
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Gunaratnam, M;
Collie, GW;
Reszka, AP;
Todd, AK;
Parkinson, GN;
Neidle, S;
(2018)
A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line.
Bioorganic & Medicinal Chemistry
, 26
(11)
pp. 2958-2964.
10.1016/j.bmc.2018.04.050.
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Guneri, Dilek;
Alexandrou, Effrosyni;
El Omari, Kamel;
Dvorakova, Zuzana;
Chikhale, Rupesh V;
Pike, Daniel TS;
Waudby, Christopher A;
... Waller, Zoe AE; + view all
(2024)
Structural insights into i-motif DNA structures in sequences from the insulin-linked polymorphic region.
Nature Communications
, 15
(1)
, Article 7119. 10.1038/s41467-024-50553-0.
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Haider, S;
Li, P;
Khiali, S;
Munnur, D;
Ramanathan, A;
Parkinson, GN;
(2018)
Holliday Junctions Formed from Human Telomeric DNA.
Journal of the American Chemical Society
, 140
(45)
pp. 15366-15374.
10.1021/jacs.8b08699.
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Haider, S;
Parkinson, GN;
Marsh, TC;
(2018)
G-Quadruplexes (GQU).
Journal of Nucleic Acids
, 2018
, Article 1079191. 10.1155/2018/1079191.
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Halliwell, Christopher A;
Jolley, Kenny;
Yendall, Keith;
Elsegood, Mark RJ;
Parkinson, Gary N;
Fernandez, Antonio;
(2024)
A Simple and Sequential Strategy for the Introduction of Complexity and Hierarchy in Hydrogen-Bonded Organic Framework (HOF) Crystals for Environmental Applications.
Angewandte Chemie: International Edition
, 63
(40)
, Article e202404452. 10.1002/anie.202404452.
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Hazel, P;
Parkinson, GN;
Neidle, S;
(2006)
Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures.
Nucleic Acids Res
, 34
(7)
2117 - 2127.
10.1093/nar/gkl182.
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Krauss, IR;
Ramaswamy, S;
Neidle, S;
Haider, S;
Parkinson, GN;
(2016)
Structural Insights into the Quadruplex-Duplex 3 ' Interface Formed from a Telomeric Repeat: A Potential Molecular Target.
Journal of the American Chemical Society
, 138
(4)
pp. 1226-1233.
10.1021/jacs.5b10492.
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Leonard, PG;
Parkinson, GN;
Gor, J;
Perkins, SJ;
Ladbury, JE;
(2010)
The absence of inorganic salt is required for the crystallization of the complete oligomerization domain of Salmonella typhimurium histone-like nucleoid-structuring protein.
ACTA CRYSTALLOGR F
, 66
(4)
421 - 425.
10.1107/S1744309110004574.
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Mori, M;
Gilardoni, E;
Regazzoni, L;
Pedretti, A;
Colombo, D;
Parkinson, G;
Asai, A;
... Gelain, A; + view all
(2020)
Towards the Inhibition of Protein–Protein Interactions (PPIs) in STAT3: Insights into a New Class of Benzothiadiazole Derivatives.
Molecules
, 25
(15)
, Article 3509. 10.3390/molecules25153509.
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Noureini, SK;
Esmaeili, H;
Abachi, F;
Khiali, S;
Islam, B;
Kuta, M;
Saboury, AA;
... Haider, S; + view all
(2017)
Selectivity of major isoquinoline alkaloids from Chelidonium majus towards telomeric G-quadruplex: A study using a transition-FRET (t-FRET) assay.
Biochimica et Biophysica Acta (BBA) - General Subjects
, 1861
(8)
pp. 2020-2030.
10.1016/j.bbagen.2017.05.002.
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Parkinson, Gary N;
Berman, Helen;
(2022)
More than forty years of nucleic acid structural science.
Bioorganic and Medicinal Chemistry
, 69
, Article 116887. 10.1016/j.bmc.2022.116887.
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Parkinson, GN;
Vines, D;
Driscoll, PC;
Djordjevic, S;
(2008)
Crystal structures of PI3K-C2 alpha PX domain indicate conformational change associated with ligand binding.
BMC STRUCT BIOL
, 8
(13)
10.1186/1472-6807-8-13.
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Shih, PC;
Yang, Y;
Parkinson, GN;
Wilderspin, A;
Wells, G;
(2018)
A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3).
Oncotarget
, 9
(66)
pp. 32690-32701.
10.18632/oncotarget.26013.
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Simone, R;
Balendra, R;
Moens, TG;
Preza, E;
Wilson, KM;
Heslegrave, A;
Woodling, NS;
... Isaacs, AM; + view all
(2018)
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
EMBO Molecular Medicine
, 10
(1)
pp. 22-31.
10.15252/emmm.201707850.
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Stowe, CL;
Burley, TA;
Allan, H;
Vinci, M;
Kramer-Marek, G;
Ciobota, DM;
Parkinson, GN;
... Pule, MA; + view all
(2019)
Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin.
eLife
, 8
, Article e45801. 10.7554/eLife.45801.
(In press).
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Taylor, Mae;
Abdullah, Nazrul Bin;
Al-Dargazelli, Ayah;
Montaner, Mireia Benito;
Kareem, Fatma;
Locks, Amy;
Cao, Zijing;
... Hilton, Stephen T; + view all
(2024)
Breaking the Access to Education Barrier: Enhancing HPLC Learning with Virtual Reality.
Journal of Chemical Education
10.1021/acs.jchemed.4c00540.
(In press).
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Todd, AK;
Haider, SM;
Parkinson, GN;
Neidle, S;
(2007)
Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter.
Nucleic Acids Res
, 35
(17)
5799 - 5808.
10.1093/nar/gkm609.
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Wei, D;
Parkinson, GN;
Reszka, AP;
Neidle, S;
(2012)
Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation.
Nucleic Acids Res
, 40
(10)
4691 - 4700.
10.1093/nar/gks023.
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Zhang, Y;
Bux, K;
Attana, F;
Wei, D;
Haider, S;
Parkinson, GN;
(2024)
Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of pseudorabies virus.
Biochimie
, 227
(A)
pp. 28-36.
10.1016/j.biochi.2024.06.003.
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Zhang, Y;
El Omari, K;
Duman, R;
Liu, S;
Haider, S;
Wagner, A;
Parkinson, GN;
(2020)
Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.
Nucleic Acids Research
10.1093/nar/gkaa439.
(In press).
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