Browse by UCL people
Group by: Type | Date
Number of items: 28.
Article
Benitez, DP;
Jiang, S;
Wood, J;
Wang, R;
Hall, CM;
Peerboom, C;
Wong, N;
... Cummings, DM; + view all
(2021)
Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia.
Molecular Neurodegeneration
, 16
(1)
, Article 47. 10.1186/s13024-021-00457-0.
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Cummings, DM;
benway, TA;
Ho, H;
Tedoldi, A;
Fernandes Freitas, MM;
Shahab, L;
Murray, CE;
... Edwards, FA; + view all
(2017)
Neuronal and Peripheral pentraxins modify glutamate release and may interact in blood-brain barrier failure.
Cerebral Cortex
, 27
(6)
pp. 3437-3448.
10.1093/cercor/bhx046.
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Cummings, DM;
Liu, W;
Portelius, E;
Bayram, S;
Yasvoina, M;
Ho, SH;
Smits, H;
... Edwards, FA; + view all
(2015)
First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression.
Brain
, 138
(7)
1992 - 2004.
10.1093/brain/awv127.
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Dean, I.;
Robertson, S.J.;
Edwards, F.A.;
(2003)
Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse.
The Journal of Neuroscience
, 23
(11)
pp. 4457-4469.
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Donato, R;
Miljan, EA;
Hines, SJ;
Aouabdi, S;
Pollock, K;
Patel, S;
Edwards, FA;
(2007)
Differential development of neuronal physiological responsiveness in two human neural stem cell lines.
BMC Neuroscience
, 8
, Article 36. 10.1186/1471-2202-8-36.
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Donato, R;
Page, KM;
Koch, D;
Nieto-Rostro, M;
Foucault, I;
Davies, A;
Wilkinson, T;
... Dolphin, AC; + view all
(2006)
The ducky^{2J} Mutation in Cacna2d2 Results in Reduced Spontaneous Purkinje Cell Activity and Altered Gene Expression.
The Journal of Neuroscience
, 26
(48)
pp. 12576-12586.
10.1523/JNEUROSCI.3080-06.2006.
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Edwards, AV;
Hann, C;
Ivill, H;
Leeson, H;
Tymczyszyn, L;
Cummings, DM;
Ashton, MD;
... Cheneler, D; + view all
(2021)
Additive manufacturing of multielectrode arrays for biotechnological applications.
Materials Advances
, 2
(5)
pp. 1600-1605.
10.1039/d0ma00484g.
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Edwards, F;
(2019)
A unifying hypothesis for Alzheimer’s disease: from plaques to neurodegeneration.
Trends in Neurosciences
, 42
(5)
pp. 310-322.
10.1016/j.tins.2019.03.003.
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Guarascio, R;
Salih, D;
Yasvoina, M;
Edwards, FA;
Cheetham, ME;
van der Spuy, J;
(2020)
Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment.
Human Molecular Genetics
, 29
(1)
pp. 80-96.
10.1093/hmg/ddz255.
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Hardy, JG;
Hernandez, DS;
Cummings, DM;
Edwards, FA;
Shear, JB;
Schmidt, CE;
(2015)
Multiphoton microfabrication of conducting polymer-based biomaterials.
Journal of Materials Chemistry B
, 2015
(25)
pp. 4935-5124.
10.1039/C5TB00104H.
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Joel, Z;
Izquierdo, P;
Salih, DA;
Richardson, JC;
Cummings, DM;
Edwards, FA;
(2019)
Improving Mouse Models for Dementia. Are All the Effects in Tau Mouse Models Due to Overexpression?
Cold Spring Harbor Symposia on Quantitative Biology
, 83
pp. 151-161.
10.1101/sqb.2018.83.037531.
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Liu, W;
Taso, O;
Wang, R;
Bayram, S;
Graham, AC;
Garcia-Reitboeck, P;
Mallach, A;
... Salih, DA; + view all
(2020)
Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.
Human Molecular Genetics
10.1093/hmg/ddaa209.
(In press).
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Matarin, M;
Perona, M;
Salih, DA;
Yasvoina, M;
Cummings, DM;
Liu, W;
NahabooSolim, MA;
... Smith, KJ; + view all
(2015)
A Genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology.
Cell Reports
, 10
(4)
633 - 645.
10.1016/j.celrep.2014.12.041.
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Medawar, E;
Benway, TA;
Liu, W;
Hanan, TA;
Haslehurst, P;
James, OT;
Yap, K;
... Edwards, FA; + view all
(2019)
Effects of rising amyloidβ levels on hippocampal synaptic transmission, microglial response and cognition in APP_{Swe}/PSEN1_{M146V} transgenic mice.
EBioMedicine
, 39
pp. 422-435.
10.1016/j.ebiom.2018.12.006.
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Michno, W;
Stringer, KM;
Enzlein, T;
Passarelli, MK;
Escrig, S;
Vitanova, K;
Wood, J;
... Hanrieder, J; + view all
(2021)
Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.
Science Advances
, 7
(25)
10.1126/sciadv.abg4855.
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Paulin, JJW;
Haslehurst, P;
Fellows, AD;
Liu, W;
Jackson, JD;
Joel, Z;
Cummings, DM;
(2016)
Large and small dendritic spines serve different functions in hippocampal synaptic plasticity.
Neural Plasticity
, 2016
, Article 617050. 10.1155/2016/6170509.
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Salih, D;
Chaney, AM;
(2021)
Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD - a multi-modal and multi-centre study.
Theranostics
, 11
(4)
pp. 6644-6667.
10.7150/thno.56059.
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Shahab, L;
Plattner, F;
Irvine, EE;
Cummings, DM;
Edwards, FA;
(2014)
Dynamic range of GSK3α not GSK3β is essential for bidirectional synaptic plasticity at hippocampal CA3-CA1 synapses.
Hippocampus
, 24
(12)
1413 - 1416.
10.1002/hipo.22362.
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Witton, J;
Padmashri, R;
Zinyuk, LE;
Popov, VI;
Kraev, I;
Line, SJ;
Jensen, TP;
... Jones, MW; + view all
(2015)
Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome.
Nature Neuroscience
, 18
(9)
pp. 1291-1298.
10.1038/nn.4072.
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Wood, Jack I;
Wong, Eugenia;
Joghee, Ridwaan;
Balbaa, Aya;
Vitanova, Karina S;
Stringer, Katie M;
Vanshoiack, Alison;
... Edwards, Frances A; + view all
(2022)
Plaque contact and unimpaired Trem2 is required for the microglial response to amyloid pathology.
Cell Reports
, 41
(8)
, Article 111686. 10.1016/j.celrep.2022.111686.
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Proceedings paper
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Guarascio, R;
Edwards, F;
Salih, D;
van der Spuy, J;
(2017)
Expression and localization of NUB1 in Tauopathy and Alzheimer’s disease models.
In:
UCL 2015 Neuroscience Symposium Poster Abstract Booklet.
UCL
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Working / discussion paper
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Desai, Sneha;
Camporesi, Elena;
Brinkmalm, Gunnar;
Alatza, Argyro;
Wood, Jack I;
Tripathi, Takshashila;
Bez, Sumi;
... Edwards, Frances A; + view all
(2024)
Age- and amyloid-β-dependent initiation of neurofibrillary tau tangles: an improved mouse model of Alzheimer’s disease without mutations in MAPT.
bioRxiv: Cold Spring Harbor, NY, USA.
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Joel, Z;
Izquierdo, P;
Liu, W;
Hall, C;
Roberts, M;
Yap, K;
Nick, A;
... Edwards, F; + view all
(2018)
A TauP301L mouse model of dementia; development of pathology, synaptic transmission, microglial response and cognition throughout life.
BioRxiv: Cold Spring Harbor, NY, USA.
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Liu, W;
Taso, O;
Wang, R;
Garcia-Reitboeck, P;
Andrews, WD;
Piers, TM;
Pocock, JM;
... Salih, D; + view all
(2018)
Trem2 promotes anti-inflammatory responses in microglia and is suppressed under pro-inflammatory conditions.
bioRxiv
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Medawar, E;
Benway, T;
Liu, W;
Hanan, TA;
Haslehurst, P;
James, OT;
Yap, K;
... Edwards, FA; + view all
(2018)
Effects of rising amyloidβ levels on hippocampal synaptic transmission, microglial response and cognition in APPSwe/PSEN1M146V transgenic mice.
BioRxiv: Cold Spring Harbor, NY, USA.
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Salih, D;
Bayram, S;
Guelfi, MS;
Reynolds, RH;
Shoai, M;
Ryten, M;
Brenton, J;
... Escott-Price, V; + view all
(2018)
Genetic variability in response to Aβ deposition influences Alzheimer's risk.
BioRxiv: Cold Spring Harbor, NY, USA.
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Wood, Jack;
Wong, Eugenia;
Joghee, Ridwaan;
Balbaa, Aya;
Vitanova, Karina S;
Vanshoiack, Alison;
Phelan, Stefan-Laural J;
... Edwards, Frances A; + view all
(2022)
Upregulation of Trem2 expression occurs exclusively on microglial contact with plaques.
BioRxiv: Cold Spring Harbor, NY, USA.
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Conference item
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Cummings, D;
Benway, T;
Foster, E;
Liu, W;
Yasvoina, M;
Lashley, T;
Murray, CE;
... Salih, D; + view all
(2016)
The pentraxin family regulates neuronal and microglial function in the CNS and is disrupted in phenotypes associated with Alzheimer’s disease.
Presented at: Alzheimer's Research UK's (ARUK) Conference 2016, Manchester, UK.
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