Browse by UCL people
Group by: Type | Date
Number of items: 21.
Article
Casas, JP;
Hingorani, AD;
(2012)
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
Lancet
, 379
(9822)
1214 - 1224.
10.1016/S0140-6736(12)60110-X.
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Gill, D;
Georgakis, MK;
Walker, VM;
Schmidt, AF;
Gkatzionis, A;
Freitag, DF;
Finan, C;
... Davies, NM; + view all
(2021)
Mendelian randomization for studying the effects of perturbing drug targets [version 1; peer review: awaiting peer review].
Wellcome Open Research
, 6
, Article 16. 10.12688/WELLCOMEOPENRES.16544.1.
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Gill, D;
Georgakis, MK;
Walker, VM;
Schmidt, AF;
Gkatzionis, A;
Freitag, DF;
Finan, C;
... Davies, NM; + view all
(2021)
Mendelian randomization for studying the effects of perturbing drug targets [version 2; peer review: 3 approved, 1 approved with reservations].
Wellcome Open Research
, 6
, Article 16. 10.12688/wellcomeopenres.16544.2.
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Harrison, SC;
Holmes, MV;
Burgess, S;
Asselbergs, FW;
Jones, GT;
Baas, AF;
van 't Hof, FN;
... Humphries, SE; + view all
(2018)
Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis.
JAMA Cardiology
, 3
(1)
pp. 26-33.
10.1001/jamacardio.2017.4293.
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Harrison, SC;
Smith, AJ;
Jones, GT;
Swerdlow, DI;
Rampuri, R;
Bown, MJ;
Aneurysm Consortium;
... Humphries, SE; + view all
(2013)
Interleukin-6 receptor pathways in abdominal aortic aneurysm.
European Heart Journal
, 34
(48)
, Article ehs354v1. 10.1093/eurheartj/ehs354.
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Holmes, MV;
Asselbergs, FW;
Palmer, TM;
Drenos, F;
Lanktree, MB;
Nelson, CP;
Dale, CE;
... Casas, JP; + view all
(2015)
Mendelian randomization of blood lipids for coronary heart disease.
Eur Heart J
, 36
(9)
539 - 550.
10.1093/eurheartj/eht571.
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Holmes, MV;
Dale, CE;
Zuccolo, L;
Silverwood, RJ;
Guo, Y;
Ye, Z;
Prieto-Merino, D;
... InterAct Consortium; + view all
(2014)
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.
BMJ
, 349
, Article g4164. 10.1136/bmj.g4164.
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Lumbers, RT;
Shah, S;
Lin, H;
Czuba, T;
Henry, A;
Swerdlow, D;
Malarstig, A;
... Smith, JG; + view all
(2021)
The genomics of heart failure: design and rationale of the HERMES consortium.
ESC Heart Failure
10.1002/ehf2.13517.
(In press).
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McLachlan, S;
Giambartolomei, C;
White, J;
Charoen, P;
Wong, A;
Finan, C;
Engmann, J;
... UCLEB Consortium; + view all
(2016)
Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans.
PLoS One
, 11
(6)
, Article e0156914. 10.1371/journal.pone.0156914.
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Schmidt, AF;
Holmes, MV;
Preiss, D;
Swerdlow, DI;
Denaxas, S;
Fatemifar, G;
Faraway, R;
... Hingorani, AD; + view all
(2019)
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
BMC Cardiovascular Disorders
, 19
(1)
, Article 240. 10.1186/s12872-019-1187-z.
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Schmidt, AF;
Swerdlow, DI;
Holmes, MV;
Patel, RS;
Fairhurst-Hunter, Z;
Lyall, DM;
Hartwig, FP;
... Sattar, N; + view all
(2017)
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
The Lancet: Diabetes and Endocrinology
, 5
(2)
pp. 97-105.
10.1016/S2213-8587(16)30396-5.
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Shah, S;
Henry, A;
Roselli, C;
Lin, H;
Sveinbjörnsson, G;
Fatemifar, G;
Hedman, ÅK;
... Lumbers, RT; + view all
(2020)
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Nature Communications
, 11
, Article 163. 10.1038/s41467-019-13690-5.
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Shah, T;
Engmann, J;
Dale, C;
Shah, S;
White, J;
Giambartolomei, C;
McLachlan, S;
... UCLEB Consortium; + view all
(2013)
Population Genomics of Cardiometabolic Traits: Design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
PLoS One
, 8
(8)
, Article e71345. 10.1371/journal.pone.0071345.
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Swerdlow, DI;
Hingorani, AD;
Humphries, SE;
(2015)
Genetic risk factors and Mendelian randomization in cardiovascular disease.
Current Cardiology Reports
, 17
(5)
, Article 33. 10.1007/s11886-015-0584-x.
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Swerdlow, DI;
Humphries, SE;
(2017)
Genetics of CHD in 2016: Common and rare genetic variants and risk of CHD.
Nature Reviews Cardiology
, 14
(2)
pp. 73-74.
10.1038/nrcardio.2016.209.
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Swerdlow, DI;
Kuchenbaecker, KB;
Shah, S;
Sofat, R;
Holmes, MV;
White, J;
Mindell, JS;
... Hingorani, AD; + view all
(2016)
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.
International Journal of Epidemiology
, 45
(5)
pp. 1600-1616.
10.1093/ije/dyw088.
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Swerdlow, DI;
Preiss, D;
Kuchenbaecker, KB;
Holmes, MV;
Engmann, JE;
Shah, T;
Sofat, R;
... Sattar, N; + view all
(2014)
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Lancet
, 385
(9965)
pp. 351-361.
10.1016/S0140-6736(14)61183-1.
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Swerdlow, DI;
Sattar, N;
(2014)
A dysglycaemic effect of statins in diabetes: relevance to clinical practice?
Diabetologia
, 57
(12)
2433 - 2435.
10.1007/s00125-014-3409-3.
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White, J;
Sofat, R;
Hemani, G;
Shah, T;
(2016)
Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.
The Lancet Diabetes and Endocrinology
, 4
(4)
pp. 327-336.
10.1016/S2213-8587(15)00386-1.
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White, J;
Swerdlow, DI;
Preiss, D;
Fairhurst-Hunter, Z;
Keating, BJ;
Asselbergs, FW;
Sattar, N;
... Holmes, MV; + view all
(2016)
Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes.
JAMA Cardiology
, 1
(6)
pp. 692-699.
10.1001/jamacardio.2016.1884.
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Thesis
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Swerdlow, DI;
(2012)
Validation of therapeutic targets in cardiometabolic disease using Mendelian randomisation.
Doctoral thesis , UCL (University College London).
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