Browse by UCL people
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Number of items: 43.
Article
Alonso-Ferrero, ME;
van Til, NP;
Bartolovic, K;
Mata, MF;
Wagemaker, G;
Moulding, D;
Williams, DA;
... Howe, SJ; + view all
(2017)
Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors.
Exp Hematol
10.1016/j.exphem.2017.09.003.
(In press).
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Apps, JR;
Hutchinson, JC;
Arthurs, OJ;
Virasami, A;
Joshi, A;
Zeller-Plumhoff, B;
Moulding, D;
... Martinez-Barbera, JP; + view all
(2016)
Imaging Invasion: Micro-CT imaging of adamantinomatous craniopharyngioma highlights cell type specific spatial relationships of tissue invasion.
Acta Neuropathol Commun
, 4
(1)
, Article 57. 10.1186/s40478-016-0321-8.
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Asfahani, R;
Tahoun, MM;
Miller-Hodges, EV;
Bellerby, J;
Virasami, AK;
Sampson, RD;
Moulding, D;
... Waters, AM; + view all
(2018)
Activation of podocyte Notch mediates early Wt1 glomerulopathy.
Kidney International
10.1016/j.kint.2017.11.014.
(In press).
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Barisa, M;
Kramer, AM;
Majani, Y;
Moulding, D;
Saraiva, L;
Bajaj-Elliott, M;
Anderson, J;
(2017)
E. coli promotes human Vγ9Vδ2 T cell transition from cytokine-producing bactericidal effectors to professional phagocytic killers in a TCR-dependent manner.
Science Reports
, 7
(1)
, Article 2805. 10.1038/s41598-017-02886-8.
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Bovellan, M;
Romeo, Y;
Biro, M;
Boden, A;
Chugh, P;
Yonis, A;
Vaghela, M;
... Charras, G; + view all
(2014)
Cellular control of cortical actin nucleation.
Curr Biol
, 24
(14)
1628 - 1635.
10.1016/j.cub.2014.05.069.
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Bryant, Dale;
Pauzuolyte, Valda;
Ingham, Neil J;
Patel, Aara;
Pagarkar, Waheeda;
Anderson, Lucy A;
Smith, Katie E;
... Bitner-Glindzicz, Maria; + view all
(2022)
The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention.
JCI Insight
, 7
(3)
, Article e148586. 10.1172/jci.insight.148586.
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Buonocore, F;
Kühnen, P;
Suntharalingham, JP;
Del Valle, I;
Digweed, M;
Stachelscheid, H;
Khajavi, N;
... Achermann, JC; + view all
(2017)
Somatic mutations and progressive monosomy modify SAMD9-related phenotypes in humans.
Journal of Clinical Investigation
, 127
(5)
pp. 1700-1713.
10.1172/JCI91913.
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Cairns, BR;
Jevans, B;
Chanpong, A;
Moulding, D;
McCann, CJ;
(2021)
Automated computational analysis reveals structural changes in the enteric nervous system of nNOS deficient mice.
Scientific Reports
, 11
, Article 17189. 10.1038/s41598-021-96677-x.
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Cannavo, C;
Cleverley, K;
Maduro, C;
Mumford, P;
Moulding, D;
Fisher, EMC;
Wiseman, FK;
(2022)
Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome.
PLoS ONE
, 17
(5)
, Article e0262558. 10.1371/journal.pone.0262558.
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Di, W-L;
Lwin, SM;
Petrova, A;
Bernadis, C;
Syed, F;
Farzaneh, F;
Moulding, DM;
... Qasim, W; + view all
(2019)
Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial.
Human Gene Therapy
, 30
(9)
pp. 1067-1078.
10.1089/hum.2019.049.
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Galea, GL;
Cho, Y-J;
Galea, G;
Mole, MA;
Rolo, A;
Savery, D;
Moulding, D;
... Copp, AJ; + view all
(2017)
Biomechanical coupling facilitates spinal neural tube closure in mouse embryos.
PNAS - Proceedings of the National Academy of Sciences of the United States of America
, 114
(26)
E5177-E5186.
10.1073/pnas.1700934114.
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Galea, GL;
Nychyk, O;
Mole, MA;
Moulding, D;
Savery, D;
Nikolopoulou, E;
Henderson, DJ;
... Copp, AJ; + view all
(2018)
Vangl2 disruption alters the biomechanics of late spinal neurulation leading to spina bifida in mouse embryos.
Disease Models & Mechanisms
, 11
(3)
, Article dmm032219. 10.1242/dmm.032219.
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Herbert, JA;
Deng, Y;
Hardelid, P;
Robinson, E;
Ren, L;
Moulding, D;
Smyth, RL;
(2020)
β2 integrin LFA1 mediates airway damage following neutrophil trans-epithelial migration during RSV infection.
European Respiratory Journal
, 56
, Article 1902216. 10.1183/13993003.02216-2019.
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Jafree, Daniyal J;
Perera, Charith;
Ball, Mary;
Tolomeo, Daniele;
Pomeranz, Gideon;
Wilson, Laura;
Davis, Benjamin;
... Long, David A; + view all
(2025)
Microvascular aberrations found in human polycystic kidneys are an early feature in a Pkd1 mutant mouse model.
DMM Disease Models and Mechanisms
10.1242/dmm.052024.
(In press).
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Jafree, DJ;
Long, DA;
Scambler, PJ;
Moulding, D;
(2019)
Tissue Clearing and Deep Imaging of the Kidney Using Confocal and Two-Photon Microscopy.
Methods in Molecular Biology
, 2067
pp. 103-126.
10.1007/978-1-4939-9841-8_8.
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Jafree, DJ;
Moulding, D;
Kolatsi-Joannou, M;
Perretta Tejedor, N;
Price, KL;
Milmoe, NJ;
Walsh, CL;
... Long, DA; + view all
(2020)
Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease.
eLife
, 8
, Article e48183. 10.7554/eLife.48183.
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Lee, DDH;
Cardinale, D;
Nigro, E;
Butler, CR;
Rutman, A;
Fassad, MR;
Hirst, RA;
... O'Callaghan, C; + view all
(2021)
Higher throughput drug screening for rare respiratory diseases: Readthrough therapy in primary ciliary dyskinesia.
European Respiratory Journal
10.1183/13993003.00455-2020.
(In press).
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Lee, KKL;
Peskett, E;
Quinn, CM;
Aiello, R;
Adeeva, L;
Moulding, DA;
Stanier, P;
(2018)
Overexpression of Fgfr2c causes craniofacial bone hypoplasia and ameliorates craniosynostosis in the Crouzon mouse.
Disease Models & Mechanisms
10.1242/dmm.035311.
(In press).
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Lee, PP;
Lobato-Márquez, D;
Pramanik, N;
Sirianni, A;
Daza-Cajigal, V;
Rivers, E;
Cavazza, A;
... Thrasher, AJ; + view all
(2017)
Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells.
Nature Communications
, 8
, Article 1576. 10.1038/s41467-017-01676-0.
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Li, Y-F;
Scerif, F;
Picker, SR;
Stone, TJ;
Pickles, JC;
Moulding, DA;
Avery, A;
... Jacques, TS; + view all
(2021)
Identifying cellular signalling molecules in developmental disorders of the brain: Evidence from focal cortical dysplasia and tuberous sclerosis.
Neuropathology and Applied Neurobiology
, 47
(6)
pp. 781-795.
10.1111/nan.12715.
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Maeshima, R;
Moulding, D;
Stoker, AW;
Hart, SL;
(2020)
MYCN Silencing by RNA Interference Induces Neurogenesis and Suppresses Proliferation in Models of Neuroblastoma with Resistance to Retinoic Acid.
Nucleic Acid Therapeutics
, 30
(4)
pp. 237-248.
10.1089/nat.2019.0831.
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Maniou, Eirini;
Todros, Silvia;
Urciuolo, Anna;
Moulding, Dale A;
Magnussen, Michael;
Ampartzidis, Ioakeim;
Brandolino, Luca;
... Elvassore, Nicola; + view all
(2024)
Quantifying mechanical forces during vertebrate morphogenesis.
Nature Materials
10.1038/s41563-024-01942-9.
(In press).
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Marshall, Abigail R;
Maniou, Eirini;
Moulding, Dale;
Greene, Nicholas DE;
Copp, Andrew J;
Galea, Gabriel L;
(2022)
Two-Photon Cell and Tissue Level Laser Ablation Methods to Study Morphogenetic Biomechanics.
Methods in Molecular Biology
, 2438
pp. 217-230.
10.1007/978-1-0716-2035-9_14.
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Moulding, DA;
Record, J;
Malinova, D;
Thrasher, AJ;
(2013)
Actin cytoskeletal defects in immunodeficiency.
Immunological Reviews
, 256
(1)
282 - 299.
10.1111/imr.12114.
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Nikolopoulou, E;
Hirst, CS;
Galea, G;
Venturini, C;
Moulding, D;
Marshall, AR;
Rolo, A;
... Greene, NDE; + view all
(2019)
Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.
Nature Communications
, 10
, Article 2487. 10.1038/s41467-019-10164-6.
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Polubothu, S;
Zecchin, D;
Al-Olabi, L;
Lionarons, DA;
Harland, M;
Horswell, S;
Thomas, AC;
... Kinsler, VA; + view all
(2021)
Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype.
Genetics in Medicine
10.1038/s41436-021-01204-y.
(In press).
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Ramanayake, S;
Moulding, DA;
Tanaka, Y;
Singh, A;
Bangham, CRM;
(2022)
Dynamics and consequences of the HTLV-1 proviral plus-strand burst.
PLOS Pathogens
, 18
(11)
, Article e1010774. 10.1371/journal.ppat.1010774.
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Rashidi, Hassan;
Cox, Helen C;
Qutachi, Omar;
Moulding, Dale;
White, Lisa J;
Smith, Emma L;
Kanczler, Janos M;
... Rose, Felicity RAJ; + view all
(2025)
Localized growth factor delivery from microparticles modulates osteogenic and chondrogenic gene expression in a growth factor-dependent manner in an ex vivo chick embryonic bone model.
Acta Biomaterialia
, 204
pp. 558-567.
10.1016/j.actbio.2025.08.028.
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Sharma, V;
Kohli, N;
Moulding, D;
Afolabi, H;
Hook, L;
Mason, C;
Garcia-Gareta, E;
(2017)
Design of a Novel Two-Component Hybrid Dermal Scaffold for the Treatment of Pressure Sores.
Macromolecular Bioscience
, 17
(11)
, Article 1700185. 10.1002/mabi.201700185.
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Standing, ASI;
Malinova, D;
Hong, Y;
Record, J;
Moulding, D;
Blundell, MP;
Nowak, K;
... Brogan, PA; + view all
(2017)
Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actinregulatory gene WDR1.
Journal of Experimental Medicine
, 214
(1)
pp. 59-71.
10.1084/jem.20161228.
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Tachner, M;
Lorentzen, A;
Maurao, A;
Collins, T;
Freke, G;
Moulding, D;
Bsquin, J;
... Lorentzen, E; + view all
(2018)
Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis.
eLife
, 7
, Article e33067. 10.7554/eLife.33067.
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Tagalakis, AD;
Munye, MM;
Ivanova, R;
Chen, H;
Smith, CM;
Aldossary, AM;
Rosa, LZ;
... Hart, SL; + view all
(2018)
Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung.
Thorax
, 73
(9)
pp. 847-856.
10.1136/thoraxjnl-2017-210670.
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Touramanidou, Loukia;
Gurung, Sonam;
Cozmescu, Claudiu A;
Perocheau, Dany;
Moulding, Dale;
Finn, Patrick F;
Frassetto, Andrea;
... Baruteau, Julien; + view all
(2024)
Macrophage Inhibitor Clodronate Enhances Liver Transduction of Lentiviral but Not Adeno-Associated Viral Vectors or mRNA Lipid Nanoparticles in Neonatal and Juvenile Mice.
Cells
, 13
(23)
, Article 1979. 10.3390/cells13231979.
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Urbani, L;
Camilli, C;
Phylactopoulos, DE;
Crowley, C;
Natarajan, D;
Scottoni, F;
Maghsoudlou, PL;
... De Coppi, P; + view all
(2018)
Multi-stage bioengineering of a layered oesophagus with in vitro expanded muscle and epithelial adult progenitors.
Nature Communications
, 9
, Article 4286. 10.1038/s41467-018-06385-w.
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Vindrola-Padrós, B;
Moulding, D;
Astaloş, C;
Virag, C;
Sommer, U;
(2019)
Working with broken agents: Exploring computational 2D morphometrics for studying the (post)depositional history of potsherds.
Journal of Archaeological Science
, 104
pp. 19-33.
10.1016/j.jas.2019.01.008.
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Wilkinson, Meredyth G Ll;
Moulding, Dale;
McDonnell, Thomas CR;
Orford, Michael;
Wincup, Chris;
Ting, Joanna YJ;
Otto, Georg W;
... Wedderburn, Lucy R; + view all
(2022)
Role of CD14+ monocyte-derived oxidised mitochondrial DNA in the inflammatory interferon type 1 signature in juvenile dermatomyositis.
Annals of the Rheumatic Diseases
10.1136/ard-2022-223469.
(In press).
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Woodall, Maximillian NJ;
Cujba, Ana-Maria;
Worlock, Kaylee B;
Case, Katie-Marie;
Masonou, Tereza;
Yoshida, Masahiro;
Polanski, Krzysztof;
... Smith, Claire M; + view all
(2024)
Author Correction: Age-specific nasal epithelial responses to SARS-CoV-2 infection.
Nature Microbiology
, 9
(11)
, Article 3076. 10.1038/s41564-024-01757-z.
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Woodall, Maximillian NJ;
Cujba, Ana-Maria;
Worlock, Kaylee B;
Case, Katie-Marie;
Masonou, Tereza;
Yoshida, Masahiro;
Polanski, Krzysztof;
... Smith, Claire M; + view all
(2024)
Age-specific nasal epithelial responses to SARS-CoV-2 infection.
Nature Microbiology
10.1038/s41564-024-01658-1.
(In press).
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Xu, Y;
Moulding, D;
Jin, W;
Beggs, S;
(2023)
Microglial phagocytosis mediates long-term restructuring of spinal GABAergic circuits following early life injury.
Brain, Behavior, and Immunity
, 111
pp. 127-137.
10.1016/j.bbi.2023.04.001.
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Conference item
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Jafree, D;
Moulding, D;
Kolatsi-Joannou, M;
Perretta Tejedor, N;
Price, K;
Walker-Samuel, S;
Riley, PR;
... Long, DA; + view all
(2019)
Using three-dimensional imaging to study how kidney lymphatic vessels develop.
Presented at: UK Kidney Week 2019, Brighton, UK.
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Jafree, D;
Moulding, D;
Kolatsi-Joannou, M;
Perretta Tejedor, N;
Price, K;
Woolf, AS;
Riley, PR;
... Long, DA; + view all
(2019)
Using three-dimensional imaging to capture kidney lymphatics in development and disease.
Presented at: 1st UK Lymphatic Science Meeting 2019, Birmingham, UK.
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Jafree, D;
Moulding, D;
Kolatsi-Joannou, M;
Woolf, AS;
Riley, P;
Scambler, P;
Long, DA;
(2018)
Dynamics and heterogeneity of renal lymphatic vessel development.
Presented at: Europhysiology 2018, London, UK.
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Jafree, D;
Moulding, D;
Kolatsi-Joannou, M;
Woolf, AS;
Riley, P;
Scambler, P;
Long, DA;
(2018)
Unravelling the origins of the renal lymphatics.
Presented at: Renaltract Conference 2018, Manchester, UK.
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