Browse by UCL people
Group by: Type | Date
Number of items: 41.
Article
Arina, P;
Baso, B;
Moro, V;
Patel, H;
Ambler, G;
Voegele, P;
Arulkumaran, N;
... Singer, M; + view all
(2021)
Discriminating between CPAP success and failure in COVID-19 patients with severe respiratory failure.
Intensive Care Medicine
, 47
pp. 237-239.
10.1007/s00134-020-06304-y.
|
|
Arulkumaran, N;
Snow, TAC;
Kulkarni, A;
Brealey, D;
Rickman, H;
Rees-Spear, C;
Spyer, MJ;
... Singer, M; + view all
(2021)
Defining Potential Therapeutic Targets in Coronavirus Disease 2019: A Cross-Sectional Analysis of a Single-Center Cohort.
Critical Care Explorations
, 3
(8)
, Article e0488. 10.1097/cce.0000000000000488.
|
 |
|
Arulkumaran, N;
Snow, TAC;
Kulkarni, A;
Brealey, D;
Rickman, HM;
Rees-Spear, C;
Spyer, MJ;
... Singer, M; + view all
(2021)
Influence of IL-6 levels on patient survival in COVID-19.
Journal of Critical Care
, 66
pp. 123-125.
10.1016/j.jcrc.2021.08.013.
|
|
|
Arulkumaran, N;
Brealey, D;
Howell, D;
Singer, M;
(2020)
Use of non-invasive ventilation for patients with COVID-19: a cause for concern?
The Lancet Respiratory Medicine
, 8
(6)
, Article e45. 10.1016/S2213-2600(20)30181-8.
|
|
|
Arulkumaran, N;
Snow, TAC;
Kulkarni, A;
Brealey, D;
Rickman, HM;
Rees-Spear, C;
Spyer, MJ;
... Singer, M; + view all
(2021)
Sex differences in immunological responses to COVID-19: a cross-sectional analysis of a single-centre cohort.
British Journal of Anaesthesia
10.1016/j.bja.2021.05.013.
(In press).
|
|
|
Arulkumaran, N;
Thomas, M;
Brealey, D;
Alwan, F;
Singh, D;
Lunn, M;
Welch, A;
... Scully, M; + view all
(2021)
Plasma exchange for COVID-19 thrombo-inflammatory disease.
EJHaem
, 2
(1)
pp. 26-32.
10.1002/jha2.140.
|
|
|
Bellingan, G;
Brealey, D;
Mancebo, J;
Mercat, A;
Patroniti, N;
Pettilä, V;
Quintel, M;
... Ranieri, VM; + view all
(2017)
Comparison of the efficacy and safety of FP-1201-lyo (intravenously administered recombinant human interferon beta-1a) and placebo in the treatment of patients with moderate or severe acute respiratory distress syndrome: study protocol for a randomized controlled trial.
Trials
, 18
, Article 536. 10.1186/s13063-017-2234-7.
|
|
|
Bloom, CI;
Drake, TM;
Docherty, AB;
Lipworth, BJ;
Johnston, SL;
Nguyen-Van-Tam, JS;
Carson, G;
... Cole, S; + view all
(2021)
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK.
The Lancet Respiratory Medicine
, 9
(7)
pp. 699-711.
10.1016/S2213-2600(21)00013-8.
|
|
|
Dark, Paul;
Hossain, Anower;
Mcauley, Daniel F;
Brealey, David;
Carlson, Gordon;
Clayton, Jonathan C;
Felton, Timothy W;
... ADAPT, Sepsis Collaborators; + view all
(2024)
Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis.
Journal of the American Medical Association (JAMA)
, 333
(8)
pp. 682-693.
10.1001/jama.2024.26458.
|
|
De Pascale, G;
Singer, M;
Brealey, D;
(2017)
Comparison of stroke volume measurement between non-invasive bioreactance and esophageal Doppler in patients undergoing major abdominal-pelvic surgery.
Journal of Anesthesia
, 31
(4)
pp. 545-551.
10.1007/s00540-017-2351-1.
|
|
Dushianthan, A;
Clark, H;
Madsen, J;
Mogg, R;
Matthews, L;
Berry, L;
De la Serna, JB;
... Grocott, MPW; + view all
(2020)
Nebulised surfactant for the treatment of severe COVID-19 in adults (COV-Surf): A structured summary of a study protocol for a randomized controlled trial.
Trials
, 21
, Article 1014. 10.1186/s13063-020-04944-5.
|
|
|
Gordon, AC;
Perkins, GD;
Singer, M;
McAuley, DF;
Orme, RML;
Santhakumaran, S;
Mason, AJ;
... Ashby, D; + view all
(2016)
Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis.
The New England Journal of Medicine
, 375
(17)
pp. 1638-1648.
10.1056/NEJMoa1609409.
|
|
Gupta, RK;
Harrison, EM;
Ho, A;
Docherty, AB;
Knight, SR;
van Smeden, M;
Abubakar, I;
... ISARIC4C Investigators; + view all
(2021)
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study.
The Lancet Respiratory Medicine
10.1016/S2213-2600(20)30559-2.
(In press).
|
|
|
Harrisa, S;
Shi, S;
Brealey, D;
MacCallum, NS;
Denaxas, S;
Perez-Suarez, D;
Ercole, A;
... Singer, M; + view all
(2018)
Critical Care Health Informatics Collaborative (CCHIC): Data, tools and methods for reproducible research: A multi-centre UK intensive care database.
International Journal of Medical Informatics
, 112
pp. 82-89.
10.1016/j.ijmedinf.2018.01.006.
|
|
High, J;
Enne, VI;
Barber, JA;
Brealey, D;
Turner, DA;
Horne, R;
Peters, M;
... INHALE Study Group; + view all
(2021)
INHALE: the impact of using FilmArray Pneumonia Panel molecular diagnostics for hospital-acquired and ventilator-associated pneumonia on antimicrobial stewardship and patient outcomes in UK Critical Care—study protocol for a multicentre randomised controlled trial.
Trials
, 22
, Article 680. 10.1186/s13063-021-05618-6.
|
|
|
Khaliq, W;
Grossmann, P;
Neugebauer, S;
Kleyman, A;
Domizi, R;
Calcinaro, S;
Brealey, D;
... Bauer, M; + view all
(2020)
Lipid metabolic signatures deviate in sepsis survivors compared to non-survivors.
Computational and Structural Biotechnology Journal
, 18
pp. 3678-3691.
10.1016/j.csbj.2020.11.009.
|
|
|
Leclerc, QJ;
Fuller, NM;
Keogh, RH;
Diaz-Ordaz, K;
Sekula, R;
Semple, MG;
ISARIC4C Investigators;
... Knight, GM; + view all
(2021)
Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England.
BMC Health Services Research
, 21
, Article 566. 10.1186/s12913-021-06509-x.
|
|
|
McNelly, AS;
Bear, DE;
Connolly, BA;
Arbane, G;
Allum, L;
Tarbhai, A;
Cooper, JA;
... Puthucheary, ZA; + view all
(2020)
Response.
Chest
, 158
(6)
pp. 2708-2711.
10.1016/j.chest.2020.08.001.
|
|
McNelly, AS;
Bear, DE;
Connolly, BA;
Arbane, G;
Allum, L;
Tarbhai, A;
Cooper, JA;
... Puthucheary, ZA; + view all
(2020)
Effect of Intermittent or Continuous Feed on Muscle Wasting in Critical Illness: A Phase 2 Clinical Trial.
Chest
, 158
(1)
pp. 183-194.
10.1016/j.chest.2020.03.045.
|
|
Meiring, C;
Dixit, A;
Harris, S;
MacCallum, NS;
Brealey, DA;
Watkinson, PJ;
Jones, A;
... Ercole, A; + view all
(2018)
Optimal intensive care outcome prediction over time using machine learning.
PLoS One
, 13
(11)
, Article e0206862. 10.1371/journal.pone.0206862.
|
|
|
Morel, J;
Hargreaves, I;
Brealey, D;
Neergheen, V;
Backman, JT;
Lindig, S;
Bläss, M;
... Singer, M; + view all
(2017)
Simvastatin pre-treatment improves survival and mitochondrial function in a 3-day fluid-resuscitated rat model of sepsis.
Clinical Science
, 131
(8)
pp. 747-758.
10.1042/CS20160802.
|
|
Moreno Sancho, F;
Tsakos, G;
Brealey, D;
Boniface, D;
Needleman, I;
(2019)
Development of a tool to assess oral health-related quality of life in patients hospitalised in critical care.
QUALITY OF LIFE RESEARCH
, 29
(2)
pp. 559-568.
10.1007/s11136-019-02335-1.
|
|
|
O'Dwyer, MJ;
Starczewska, MH;
Schrenzel, J;
Zacharowski, K;
Ecker, DJ;
Sampath, R;
Brealey, D;
... Vincent, JL; + view all
(2017)
The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis-a prospective multi-centre European observational study.
Clinical Microbiology and Infection Volume 23, Issue 3, March 2017, Pages
, 23
(3)
208.e1-208.e6.
10.1016/j.cmi.2016.11.010.
|
|
Palmer, E;
Post, B;
Klapaukh, R;
Marra, G;
MacCallum, NS;
Brealey, D;
Ercole, A;
... Harris, S; + view all
(2019)
The Association Between Supra-Physiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients: A Multi-Centre Observational Cohort Study.
American Journal of Respiratory and Critical Care Medicine
, 200
(11)
pp. 1373-1380.
10.1164/rccm.201904-0849OC.
|
|
Pandolfo, A;
Horne, R;
Jani, Y;
Reader, TW;
Bidad, N;
Brealey, D;
Enne, VI;
... Brett, SJ; + view all
(2021)
Intensivists’ beliefs about rapid multiplex molecular diagnostic testing and its potential role in improving prescribing decisions and antimicrobial stewardship: a qualitative study.
Antimicrobial Resistance and Infection Control
, 10
, Article 95. 10.1186/s13756-021-00961-4.
|
|
|
Pandolfo, A;
Horne, R;
Jani, Y;
Reader, TW;
Bidad, N;
Brealey, D;
Enne, VI;
... Brett, SJ; + view all
(2021)
Understanding decisions about antibiotic prescribing in ICU: an application of the Necessity Concerns Framework.
BMJ Quality and Safety
10.1136/bmjqs-2020-012479.
(In press).
|
|
Parker, T;
Brealey, D;
Dyson, A;
Singer, M;
(2019)
Optimising organ perfusion in the high-risk surgical and critical care patient: a narrative review.
British Journal of Anaesthesia
, 123
(2)
pp. 170-176.
10.1016/j.bja.2019.03.027.
|
|
|
Ranieri, VM;
Pettila, V;
Karvonen, MK;
Jalkanen, J;
Nightingale, P;
Brealey, D;
Mancebo, J;
... Bellingan, G; + view all
(2020)
Effect of Intravenous Interferon beta-1a on Death and Days Free From Mechanical Ventilation Among Patients With Moderate to Severe Acute Respiratory Distress Syndrome A Randomized Clinical Trial.
JAMA
, 323
(8)
pp. 725-733.
10.1001/jama.2019.22525.
|
|
Rowan, KM;
Angus, DC;
Bailey, M;
Barnato, AE;
Bellomo, R;
Canter, RR;
Coats, TJ;
... Yealy, DM; + view all
(2017)
Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.
New England Journal of Medicine
, 376
(23)
pp. 2223-2234.
10.1056/NEJMoa1701380.
|
|
Shah, AD;
MacCallum, NS;
Harris, S;
Brealey, DA;
Palmer, E;
Hetherington, J;
Shi, S;
... Singer, M; + view all
(2021)
Descriptors of Sepsis Using the Sepsis-3 Criteria: A Cohort Study in Critical Care Units Within the U.K. National Institute for Health Research Critical Care Health Informatics Collaborative.
Critical Care Medicine
, 49
(11)
pp. 1883-1894.
10.1097/CCM.0000000000005169.
|
|
Shipley, RJ;
Brealey, D;
Haniffa, R;
Elwell, C;
Baker, T;
Lomas, DA;
Singer, M;
(2021)
Lessons and risks of medical device deployment in a global pandemic.
The Lancet Global Health
10.1016/S2214-109X(21)00028-0.
(In press).
|
|
|
Singer, M;
Shipley, R;
Baker, T;
Cowell, A;
Brealey, D;
Lomas, D;
(2020)
The UCL Ventura CPAP device for COVID-19.
The Lancet Respiratory Medicine
, 8
(11)
pp. 1076-1078.
10.1016/S2213-2600(20)30422-7.
|
|
|
Swann, OV;
Holden, KA;
Turtle, L;
Pollock, L;
Fairfield, CJ;
Drake, TM;
Seth, S;
... ISARIC4C Investigators; + view all
(2020)
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study.
BMJ
, 370
, Article m3249. 10.1136/bmj.m3249.
(In press).
|
|
|
Terrett, Alice;
Van Loo, Magalie;
Sundararajan, Krishnaswamy;
Brealey, David;
Singer, Mervyn;
Manson, Jessica;
Raith, Eamon Patrick;
(2025)
Immune biomarkers and secondary hemophagocytic lymphohistiocytosis: a scoping review protocol.
JBI Evidence Synthesis
, 23
(1)
pp. 158-164.
10.11124/JBIES-24-00133.
|
|
Tissot, HC;
Shah, AD;
Brealey, D;
Harris, S;
Agbakoba, R;
Folarin, A;
Romao, L;
... Asselbergs, FW; + view all
(2020)
Natural language processing for mimicking clinical trial recruitment in critical care: a semi-automated simulation based on the LeoPARDS trial.
IEEE Journal of Biomedical and Health Informatics
10.1109/JBHI.2020.2977925.
(In press).
|
|
|
van Valburg, MK;
Arbous, MS;
Georgieva, M;
Brealey, DA;
Singer, M;
Geerts, BF;
(2018)
Clinical Predictors of Survival and Functional Outcome of Stroke Patients Admitted to Critical Care.
Critical Care Medicine
, 46
(7)
pp. 1085-1092.
10.1097/CCM.0000000000003127.
|
|
Welte, T;
Dellinger, RP;
Ebelt, H;
Ferrer, M;
Opal, SM;
Singer, M;
Vincent, J-L;
... Torres, A; + view all
(2018)
Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).
Intensive Care Medicine
, 44
(4)
pp. 438-448.
10.1007/s00134-018-5143-7.
|
|
|
Williams, AE;
José, RJ;
Mercer, PF;
Brealey, D;
Parekh, D;
Thickett, DR;
O'Kane, C;
... Chambers, RC; + view all
(2017)
Evidence for chemokine synergy during neutrophil migration in ARDS.
Thorax
, 72
(1)
pp. 66-73.
10.1136/thoraxjnl-2016-208597.
|
|
Wilson, P;
Gurusamy, KS;
Morley, R;
Whiting, C;
Maeso, B;
FitzGerald, G;
Bennett, S;
... Tingle, A; + view all
(2019)
Top research priorities in healthcare-associated infection in the UK.
Journal of Hospital Infection
, 103
(4)
pp. 382-287.
10.1016/j.jhin.2019.08.013.
|
|
Zimmermann, Tobias;
Brealey, David;
Singer, Mervyn;
(2024)
Diagnosing sepsis: where we’re at and where we’re going.
Intensive Care Medicine
, 50
pp. 957-959.
10.1007/s00134-024-07428-1.
|
Poster
|
Pandolfo, A;
Horne, R;
Jani, Y;
Bidad, N;
Brett, S;
Reader, TW;
Brealey, D;
... Gant, V; + view all
(2020)
Antibiotic prescribing decisions in intensive care: A qualitative study.
Presented at: ISICEM 2020 – 40th International Symposium on Intensive Care & Emergency Medicine, Brussels, Belgium.
|
