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Number of items: 12.
Article
Collinge, J;
Purro, SA;
Nicoll, A;
(2018)
Prion Protein as a Toxic Acceptor of Amyloid-β Oligomers.
Biological Psychiatry
, 83
(4)
pp. 358-368.
10.1016/j.biopsych.2017.11.020.
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Fratta, P;
Mizielinska, S;
Nicoll, AJ;
Zloh, M;
Fisher, EM;
Parkinson, G;
Isaacs, AM;
(2012)
C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.
Scientific Reports
, 2
, Article 1016. 10.1038/srep01016.
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Freir, DB;
Nicoll, AJ;
Klyubin, I;
Panico, S;
Mc Donald, JM;
Risse, E;
Asante, EA;
... Collinge, J; + view all
(2011)
Interaction between prion protein and toxic amyloid beta assemblies can be therapeutically targeted at multiple sites.
Nature Communications
, 2
, Article 336. 10.1038/ncomms1341.
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Hu, NW;
Nicoll, AJ;
Zhang, D;
Mably, AJ;
O'Malley, T;
Purro, SA;
Terry, C;
... Rowan, MJ; + view all
(2014)
mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo.
Nature Communications
, 5
, Article 3374. 10.1038/ncomms4374.
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Klyubin, I;
Nicoll, AJ;
Khalili-Shirazi, A;
Farmer, M;
Canning, S;
Mably, A;
Linehan, J;
... Collinge, J; + view all
(2014)
Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity.
J Neurosci
, 34
(18)
6140 - 6145.
10.1523/JNEUROSCI.3526-13.2014.
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Mizielinska, S;
Grönke, S;
Niccoli, T;
Ridler, CE;
Clayton, EL;
Devoy, A;
Moens, T;
... Isaacs, AM; + view all
(2014)
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins.
Science
10.1126/science.1256800.
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Nicoll, AJ;
Panico, S;
Freir, DB;
Wright, D;
Terry, C;
Risse, E;
Herron, CE;
... Collinge, J; + view all
(2013)
Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity.
Nature Communications
, 4
, Article 2416 . 10.1038/ncomms3416.
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Risse, E;
Nicoll, AJ;
Taylor, WA;
Wright, D;
Badoni, M;
Yang, X;
Farrow, MA;
(2015)
Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay.
Journal of Biological Chemistry
, 290
(27)
pp. 17020-17028.
10.1074/jbc.M115.637124.
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Sarell, CJ;
Quarterman, E;
Yip, DC-M;
Terry, C;
Nicoll, AJ;
Wadsworth, JDF;
Farrow, MA;
... Collinge, J; + view all
(2017)
Soluble A beta aggregates can inhibit prion propagation.
Open Biology
, 7
(11)
, Article 170158. 10.1098/rsob.170158.
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Sarell, CJ;
Quarterman, E;
Yip, DC-M;
Terry, C;
Nicoll, AJ;
Wadsworth, JDF;
Farrow, MA;
... Collinge, J; + view all
(2017)
Soluble Aβ aggregates can inhibit prion propagation.
Open Biology
, 7
(11)
, Article 170158. 10.1098/rsob.170158.
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Simone, R;
Balendra, R;
Moens, TG;
Preza, E;
Wilson, KM;
Heslegrave, A;
Woodling, NS;
... Isaacs, AM; + view all
(2018)
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
EMBO Molecular Medicine
, 10
(1)
pp. 22-31.
10.15252/emmm.201707850.
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Trevitt, CR;
Hosszu, LL;
Batchelor, M;
Panico, S;
Terry, C;
Nicoll, AJ;
Risse, E;
... Clarke, AR; + view all
(2014)
N-terminal domain of prion protein directs its oligomeric association.
J Biol Chem
, 289
(37)
25497 - 25508.
10.1074/jbc.M114.566588.
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