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Number of items: 47.
B
Babcock, MC;
Mikulka, CR;
Wang, B;
Chandriani, S;
Chandra, S;
Xu, Y;
Webster, K;
... Crawford, BE; + view all
(2021)
Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor.
Scientific Reports
, 11
, Article 14486. 10.1038/s41598-021-93601-1.
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Barbier, M;
Camuzat, A;
Hachimi, KE;
Guegan, J;
Rinaldi, D;
Lattante, S;
Houot, M;
... Le Ber, I; + view all
(2021)
SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration.
Brain
, 144
(9)
pp. 2798-2811.
10.1093/brain/awab171.
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Bashir, S;
Dziemidowicz, K;
(2021)
Critical appraisal: how to evaluate research for use inclinical practice.
The Pharmaceutical Journal
, 306
(7950)
pp. 1-15.
10.1211/PJ.2021.1.85492.
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Blauwendraat, C;
Iwaki, H;
Makarious, MB;
Bandres-Ciga, S;
Leonard, H;
Grenn, FP;
Lake, J;
... Lynch, TL; + view all
(2021)
Investigation of Autosomal Genetic Sex Differences in Parkinson's disease.
Annals of Neurology
, 90
(1)
pp. 35-42.
10.1002/ana.26090.
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C
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Chen, Z;
Zhang, D;
Reynolds, RH;
Gustavsson, EK;
García-Ruiz, S;
D'Sa, K;
Fairbrother-Browne, A;
... Ryten, M; + view all
(2021)
Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage.
Nature Communications
, 12
, Article 2076. 10.1038/s41467-021-22262-5.
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Citraro, R;
Lembo, F;
De Caro, C;
Tallarico, M;
Coretti, L;
Iannone, LF;
Leo, A;
... De Sarro, G; + view all
(2021)
First evidence of an altered microbiota and intestinal damage and its link to absence epilepsy in a genetic animal model, the WAG/Rij rat.
Epilepsia
, 62
(2)
pp. 529-541.
10.1111/epi.16813.
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Coy, R;
Berg, M;
Phillips, JB;
Shipley, RJ;
(2021)
Modelling-informed cell-seeded nerve repair construct designs for treating peripheral nerve injuries.
PLoS Computational Biology
, 17
(7)
, Article e1009142. 10.1371/journal.pcbi.1009142.
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D
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D'Agate, S;
Chavan, C;
Manyak, M;
Palacios-Moreno, JM;
Oelke, M;
Michel, MC;
Roehrborn, CG;
(2021)
Model-based meta-analysis of the time to first acute urinaryretention or benign prostatic hyperplasia-related surgery inpatients with moderate or severe symptoms.
British Journal of Clinical Pharmacology
10.1111/bcp.14682.
(In press).
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D'Agate, S;
Musuamba, FT;
Jacqz-Aigrain, E;
Della Pasqua, O;
(2021)
Simplified Dosing Regimens for Gentamicin in Neonatal Sepsis.
FrFrontiers in Pharmacology
, 12
, Article 624662. 10.3389/fphar.2021.624662.
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F
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Fullerton, JN;
Della Pasqua, O;
Likic, R;
(2021)
Model antibiotic use to improve outcomes.
British Journal of Clinical Pharmacology
, 87
(3)
pp. 738-740.
10.1111/bcp.14559.
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G
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Gregory, H;
Phillips, JB;
(2021)
Materials for peripheral nerve repair constructs: Natural proteins or synthetic polymers?
Neurochemistry International
, 143
, Article 104953. 10.1016/j.neuint.2020.104953.
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K
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Kara, E;
Crimi, A;
Wiedmer, A;
Emmenegger, M;
Manzoni, C;
Bandres-Ciga, S;
D'Sa, K;
... Aguzzi, A; + view all
(2021)
An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein.
Cell Reports
, 35
(10)
, Article 109189. 10.1016/j.celrep.2021.109189.
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Kellaway, Simon Christopher;
(2021)
Hydrogels derived from decellularised tissues for nerve repair.
Doctoral thesis (Ph.D), UCL (University College London).
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Kia, DA;
Zhang, D;
Guelfi, S;
Manzoni, C;
Hubbard, L;
Reynolds, RH;
Botía, J;
... Botiá, JA; + view all
(2021)
Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets.
JAMA Neurology
, 78
(4)
pp. 464-472.
10.1001/jamaneurol.2020.5257.
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Klionsky, DJ;
Abdel-Aziz, AK;
Abdelfatah, S;
Abdellatif, M;
Abdoli, A;
Abel, S;
Abeliovich, H;
... Taylor, A; + view all
(2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Autophagy
, 17
(1)
pp. 1-382.
10.1080/15548627.2020.1797280.
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Kluss, JH;
Mazza, MC;
Li, Y;
Manzoni, C;
Lewis, PA;
Cookson, MR;
Mamais, A;
(2021)
Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo.
Molecular Neurodegeneration
, 16
(1)
, Article 17. 10.1186/s13024-021-00441-8.
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L
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Leo, A;
De Caro, C;
Mainardi, P;
Tallarico, M;
Nesci, V;
Marascio, N;
Striano, P;
... Citraro, R; + view all
(2021)
Increased efficacy of combining prebiotic and postbiotics approaches in mouse models relevant to autism and depression.
Neuropharmacology
, 198
, Article 108782. 10.1016/j.neuropharm.2021.108782.
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M
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Manzoni, C;
Ferrari, R;
(2021)
Mendelian and Sporadic FTD: Disease Risk and Avenues from Genetics to Disease Pathways Through In Silico Modelling.
Advances in Experimental Medicine and Biology
, 1281
pp. 283-296.
10.1007/978-3-030-51140-1_17.
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Massaro, G;
Geard, AF;
Liu, W;
Coombe-Tennant, O;
Waddington, SN;
Baruteau, J;
Gissen, P;
(2021)
Gene Therapy for Lysosomal Storage Disorders: Ongoing Studies and Clinical Development.
Biomolecules
, 11
(4)
, Article 611. 10.3390/biom11040611.
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Muangsanit, P;
Roberton, V;
Costa, E;
Phillips, JB;
(2021)
Engineered aligned endothelial cell structures in tethered collagen hydrogels promote peripheral nerve regeneration.
Acta Biomaterialia
, 126
pp. 224-237.
10.1016/j.actbio.2021.03.039.
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Muliaditan, M;
Della Pasqua, O;
(2021)
Bacterial growth dynamics and PKPD relationships of rifampicin and bedaquiline in BALB/c mice.
British Journal of Pharmacology
, 179
(6)
pp. 1251-1263.
10.1111/bph.15688.
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N
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Nelvagal, HR;
Dearborn, JT;
Ostergaard, JR;
Sands, MS;
Cooper, JD;
(2021)
Spinal manifestations of CLN1 disease start during the early postnatal period.
Neuropathology and Applied Neurobiology
, 47
(2)
pp. 251-267.
10.1111/nan.12658.
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Ng, J;
Barral, S;
Barrigon, CDLF;
Lignani, G;
Erdem, FA;
Wallings, R;
Privolizzi, R;
... Kurian, MA; + view all
(2021)
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism.
Science Translational Medicine
, 13
(594)
, Article eaaw1564. 10.1126/scitranslmed.aaw1564.
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O
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Oosterholt, SP;
Della Pasqua, O;
(2021)
Extrapolation and dosing recommendations for raxibacumab in children from birth to < 18 years of age.
British Journal of Clinical Pharmacology
10.1111/bcp.14893.
(In press).
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Oosterholt, SP;
Della Pasqua, O;
(2021)
Population pharmacokinetics of raxibacumab in healthy adult subjects.
British Journal of Clinical Pharmacology
10.1111/bcp.14894.
(In press).
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P
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Phillips, JB;
(2021)
'EngNT' - Engineering live neural tissue for nerve replacemen.
Emerging Topics in Life Sciences
10.1042/ETLS20210085.
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Powell, R;
Phillips, JB;
(2021)
Engineered Tissues Made from Human iPSC-Derived Schwann Cells for Investigating Peripheral Nerve Regeneration In Vitro.
Methods in Molecular Biology
, 2269
pp. 245-254.
10.1007/978-1-0716-1225-5_17.
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Powell, R;
Eleftheriadou, D;
Kellaway, S;
Phillips, JB;
(2021)
Natural Biomaterials as Instructive Engineered Microenvironments That Direct Cellular Function in Peripheral Nerve Tissue Engineering.
Frontiers in Bioengineering and Biotechnology
, 9
, Article 674473. 10.3389/fbioe.2021.674473.
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R
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Rayner, MLD;
Day, AGE;
Bhangra, KS;
Sinden, J;
Phillips, JB;
(2021)
Engineered neural tissue made using clinical-grade human neural stem cells supports regeneration in a long gap peripheral nerve injury model.
Acta Biomaterialia
, 135
pp. 203-213.
10.1016/j.actbio.2021.08.030.
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Rayner, MLD;
Healy, J;
Phillips, JB;
(2021)
Repurposing small molecules to target ppar-γ as new therapies for peripheral nerve injuries.
Biomolecules
, 11
(9)
, Article 1301. 10.3390/biom11091301.
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Roberton, VH;
(2021)
The Immune Response and Implications for Nerve Repair.
In: Phillips, J and Hercher, D and Hausner, T, (eds.)
Peripheral Nerve Tissue Engineering and Regeneration.
(pp. 1-30).
Springer Nature: Cham, Switzerland.
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Romano, F;
D’Agate, S;
Della Pasqua, O;
(2021)
Model-informed repurposing of medicines for SARS-CoV-2: extrapolation of antiviral activity and dose rationale for paediatric patients.
Pharmaceutics
, 13
(8)
, Article 1299. 10.3390/pharmaceutics13081299.
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S
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Sancandi, Marco;
(2021)
Exploring the aetiology of pre-motor Parkinson's disease and the efficacy of potential neuroprotective therapies.
Doctoral thesis (Ph.D), UCL (University College London).
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Seixas-Moizes, J;
Boerlage, A;
Lia, EN;
Lopes e Santos, LE;
Zucoloto, ML;
Dach, F;
Papassidero, PC;
... Wichert-Ana, L; + view all
(2021)
Translation, cross-cultural adaptation, and validation of the Portuguese version of the Rotterdam Elderly Pain Observation Scale (REPOS).
Dementia and Geriatric Cognitive Disorders
(In press).
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Shah, MM;
(2021)
A new HCN1 channelopathy: implications for epilepsy.
Brain
, 144
(7)
pp. 1939-1940.
10.1093/brain/awab220.
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Simone, R;
Javad, F;
Emmett, W;
Wilkins, OG;
Almeida, FL;
Barahona-Torres, N;
Zareba-Paslawska, J;
... De Silva, R; + view all
(2021)
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration.
Nature
, 594
pp. 117-123.
10.1038/s41586-021-03556-6.
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Storm, CS;
Kia, DA;
Almramhi, MM;
Bandres-Ciga, S;
Finan, C;
Hingorani, AD;
Wood, NW;
(2021)
Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome.
Nature Communications
, 12
(1)
, Article 7342. 10.1038/s41467-021-26280-1.
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Sun, H;
Yi, M;
Wan, Y;
(2021)
Conditional Gene Editing in Presynaptic Extinction-ensemble Cells via the CRISPR-SaCas9 System.
Bio-protocol
, 11
(23)
, Article e4246. 10.21769/BioProtoc.4246.
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T
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Tawfik, EA;
Alshamsan, A;
Abul Kalam, M;
Raish, M;
Alkholief, M;
Stapleton, P;
Harvey, K;
... Barker, SA; + view all
(2021)
In vitro and in vivo biological assessment of dual drug-loaded coaxial nanofibers for the treatment of corneal abrasion.
International Journal of Pharmaceutics
, 604
, Article 120732. 10.1016/j.ijpharm.2021.120732.
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Thomson, AM;
(2021)
Circuits and Synapses: Hypothesis, Observation, Controversy and Serendipity – An Opinion Piece.
Frontiers in Neural Circuits
, 15
10.3389/fncir.2021.732315.
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Tomkins, JE;
Manzoni, C;
(2021)
Advances in protein-protein interaction network analysis for Parkinson's disease.
Neurobiology of Disease
, 155
, Article 105395. 10.1016/j.nbd.2021.105395.
(In press).
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V
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Vavouraki, N;
Tomkins, JE;
Kara, E;
Houlden, H;
Hardy, J;
Tindall, MJ;
Lewis, PA;
(2021)
Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias.
iScience
, Article 102484. 10.1016/j.isci.2021.102484.
(In press).
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Victor, S;
Rocha-Ferreira, E;
Rahim, A;
Hagberg, H;
Edwards, D;
(2021)
New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy.
European Journal of Pediatrics
10.1007/s00431-021-04320-8.
(In press).
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W
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White, KA;
Nelvagal, HR;
Poole, TA;
Lu, B;
Johnson, TB;
Davis, S;
Pratt, MA;
... Weimer, JM; + view all
(2021)
Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice.
Molecular Therapy - Methods and Clinical Development
, 20
pp. 497-507.
10.1016/j.omtm.2020.12.014.
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Wilcox, M;
Dos Santos Canas, L;
Hargunani, R;
Tidswell, T;
Brown, H;
Modat, M;
Phillips, JB;
... Quick, T; + view all
(2021)
Volumetric MRI is a promising outcome measure of muscle reinnervation.
Scientific Reports
, 11
, Article 22433. 10.1038/s41598-021-01342-y.
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Wilcox, MB;
Jessen, KR;
Quick, TJ;
Phillips, JB;
(2021)
The molecular profile of nerve repair: humans mirror rodents.
Neural Regen Research
, 16
(7)
pp. 1440-1441.
10.4103/1673-5374.301014.
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Y
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Yaghini, E;
Tacconi, E;
Pilling, A;
Rahman, P;
Broughton, J;
Naasani, I;
Keshtgar, MRS;
... Della Pasqua, O; + view all
(2021)
Population pharmacokinetic modelling of indium-based quantum dot nanoparticles: preclinical in vivo studies.
European Journal of Pharmaceutical Sciences
, 157
, Article 105639. 10.1016/j.ejps.2020.105639.
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