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Number of items: 43.
Article
Bartlett, R;
Phillips, J;
Choi, D;
(2019)
Letter to the Editor, response to: ‘Intramedullary cervical spinal mass after stem cell transplantation using an olfactory mucosal cell autograft’ by Woodworth et al. July 2019.
[Letter].
Canadian Medical Association Journal
, 191
(27)
E761-E764.
10.1503/cmaj.181696.
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Bernareggi, A;
Conte, G;
Constanti, A;
Borelli, V;
Vita, F;
Zabucchi, G;
(2019)
On the mechanism of the electrophysiological changes and membrane lesions induced by asbestos fiber exposure in Xenopus laevis oocytes.
Scientific Reports
, 9
, Article 2014. 10.1038/s41598-019-38591-x.
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Berwick, DC;
Heaton, GR;
Azeggagh, S;
Harvey, K;
(2019)
LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same.
Molecular Neurodegeneration
, 14
(1)
, Article 49. 10.1186/s13024-019-0344-2.
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Bonham, LW;
Steele, NZR;
Karch, CM;
Broce, I;
Geier, EG;
Wen, NL;
Momeni, P;
... International FTD-Genomics Consortium (IFGC), .; + view all
(2019)
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia.
Scientific Reports
, 9
, Article 10854. 10.1038/s41598-019-46415-1.
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Borella, E;
Oosterholt, S;
Magni, P;
Pasqua, OD;
(2019)
Use of prior knowledge and extrapolation in paediatric drug development: A case study with deferasirox.
European Journal of Pharmaceutical Sciences
, 136
, Article 104931. 10.1016/j.ejps.2019.05.009.
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Chiou, T-T;
Long, P;
Schumann-Gillett, A;
Kanamarlapudi, K;
Haas, SA;
Harvey, K;
O’Mara, ML;
... Harvey, RJ; + view all
(2019)
Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability.
Frontiers in Molecular Neuroscience
, 12
, Article 60. 10.3389/fnmol.2019.00060.
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Citraro, R;
Iannone, M;
Leo, A;
De Caro, C;
Nesci, V;
Tallarico, M;
Abdalla, K;
... Russo, E; + view all
(2019)
Evaluation of the effects of liraglutide on the development of epilepsy and behavioural alterations in two animal models of epileptogenesis.
Brain Research Bulletin
, 153
pp. 133-142.
10.1016/j.brainresbull.2019.08.001.
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Clout, AE;
Della Pasqua, O;
Hanna, MG;
Orlu, M;
Pitceathly, RDS;
(2019)
Drug repurposing in neurological diseases: an integrated approach to reduce trial and error.
Journal of Neurology, Neurosurgery and Psychiatry
, 90
(11)
pp. 1270-1275.
10.1136/jnnp-2019-320879.
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De Caro, C;
Iannone, LF;
Citraro, R;
Striano, P;
De Sarro, G;
Constanti, A;
Cryan, JF;
(2019)
Can we ‘seize’ the gut microbiota to treat epilepsy?
Neuroscience & Biobehavioral Reviews
, 107
pp. 750-764.
10.1016/j.neubiorev.2019.10.002.
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De Caro, C;
Leo, A;
Nesci, V;
Ghelardini, C;
di Cesare Mannelli, L;
Striano, P;
Avagliano, C;
... Russo, E; + view all
(2019)
Intestinal inflammation increases convulsant activity and reduces antiepileptic drug efficacy in a mouse model of epilepsy.
Scientific Reports
, 9
, Article 13983. 10.1038/s41598-019-50542-0.
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De Leeuw, TG;
Mangiarini, L;
Lundin, R;
Kaguelidou, F;
Van Der Zanden, T;
Della Pasqua, O;
Tibboel, D;
... De Wildt, SN; + view all
(2019)
Correction to: Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial.
[Corrigendum].
Trials
, 20
, Article 368. 10.1186/s13063-019-3519-9.
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De Leeuw, TG;
Mangiarini, L;
Lundin, R;
Kaguelidou, F;
Van der Zanden, T;
Della Pasqua, O;
Tibboel, D;
... GAPP consortium; + view all
(2019)
Gabapentin as add-on to morphine for severe neuropathic or mixed pain in children from age 3 months to 18 years - evaluation of the safety, pharmacokinetics, and efficacy of a new gabapentin liquid formulation: study protocol for a randomized controlled trial.
Trials
, 20
, Article 49. 10.1186/s13063-018-3169-3.
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Gambarotta, G;
Raimondo, S;
Udina, E;
Phillips, JB;
Haastert-Talini, K;
(2019)
Editorial: Peripheral Nerve Regeneration.
Frontiers in Cellular Neuroscience
, 13
, Article 464. 10.3389/fncel.2019.00464.
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Glaze, DG;
Neul, JL;
Kaufmann, WE;
Berry-Kravis, E;
Condon, S;
Stoms, G;
Oosterholt, S;
... Percy, AK; + view all
(2019)
Double-Blind, Randomized, Placebo-Controlled Study of Trofinetide in Pediatric Rett Syndrome.
Neurology
, 92
(16)
e1912-e1925.
10.1212/WNL.0000000000007316.
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Granno, S;
Nixon-Abell, J;
Berwick, DC;
Tosh, J;
Heaton, G;
Almudimeegh, S;
Nagda, Z;
... Harvey, K; + view all
(2019)
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus.
Scientific Reports
, 9
(1)
, Article 7322. 10.1038/s41598-019-43820-4.
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Harvey, K;
Outeiro, TF;
(2019)
The role of LRRK2 in cell signalling.
Biochemical Society Transactions
, 47
(1)
pp. 197-207.
10.1042/BST20180464.
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Holthaus, S-MK;
Herranz-Martin, S;
Massaro, G;
Aristorena, M;
Hoke, J;
Hughes, MP;
Maswood, R;
... Ali, RR; + view all
(2019)
Neonatal brain-directed gene therapy rescues a mouse model of neurodegenerative CLN6 Batten disease.
Human Molecular Genetics
, 28
(23)
pp. 3867-3879.
10.1093/hmg/ddz210.
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Hossain, ASMMA;
Sil, BC;
Iliopoulos, F;
Lever, R;
Hadgraft, J;
Lane, ME;
(2019)
Preparation, Characterisation, and Topical Delivery of Terbinafine.
Pharmaceutics
, 11
(10)
, Article 548. 10.3390/pharmaceutics11100548.
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Kaguelidou, F;
Le Roux, E;
Mangiarini, L;
Lundin, R;
de Leeuw, TG;
Della Pasqua, O;
Felisi, M;
... GAPP consortium, .; + view all
(2019)
Non-inferiority double-blind randomised controlled trial comparing gabapentin versus tramadol for the treatment of chronic neuropathic or mixed pain in children and adolescents: the GABA-1 trial-a study protocol.
BMJ Open
, 9
(2)
, Article e023296. 10.1136/bmjopen-2018-023296.
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Kayal, C;
Shipley, RJ;
Phillips, JB;
(2019)
Physical and mechanical properties of RAFT-stabilised collagen gels for tissue engineering applications.
Journal of the Mechanical Behavior of Biomedical Materials
, 99
pp. 216-224.
10.1016/j.jmbbm.2019.07.011.
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Kloprogge, F;
Hammond, R;
Copas, A;
Gillespie, SH;
Della Pasqua, O;
(2019)
Can phenotypic data complement our understanding of antimycobacterial effects for drug combinations?
Journal of Antimicrobial Chemotherapy
, 74
(12)
pp. 3530-3536.
10.1093/jac/dkz369.
(In press).
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Kloprogge, F;
Hammond, R;
Kipper, K;
Gillespie, SH;
Della Pasqua, O;
(2019)
Mimicking in-vivo exposures to drug combinations in-vitro: anti-tuberculosis drugs in lung lesions and the hollow fiber model of infection.
Scientific Reports
, 9
, Article 13228. 10.1038/s41598-019-49556-5.
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Lambert, JRA;
Howe, SJ;
Rahim, AA;
Burke, DG;
Heales, SJR;
(2019)
Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells.
International Journal of Molecular Sciences
, 20
(18)
, Article 4349. 10.3390/ijms20184349.
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Lee, H;
Phillips, JB;
Hall, RM;
Tipper, JL;
(2019)
Neural cell responses to wear debris from metal-on-metal total disc replacements.
European Spine Journal
10.1007/s00586-019-06177-w.
(In press).
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Leo, A;
De Caro, C;
Nesci, V;
Palma, E;
Tallarico, M;
Iannone, M;
Constanti, A;
... Citraro, R; + view all
(2019)
Antiepileptogenic effects of Ethosuximide and Levetiracetam in WAG/Rij rats are only temporary.
Pharmacological Reports
, 71
(5)
pp. 833-838.
10.1016/j.pharep.2019.04.017.
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Medawar, E;
Benway, TA;
Liu, W;
Hanan, TA;
Haslehurst, P;
James, OT;
Yap, K;
... Edwards, FA; + view all
(2019)
Effects of rising amyloidβ levels on hippocampal synaptic transmission, microglial response and cognition in APP_{Swe}/PSEN1_{M146V} transgenic mice.
EBioMedicine
, 39
pp. 422-435.
10.1016/j.ebiom.2018.12.006.
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Mole, SE;
Anderson, G;
Band, HA;
Berkovic, SF;
Cooper, JD;
Kleine Holthaus, S-M;
McKay, TR;
... Smith, AJ; + view all
(2019)
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis.
[Review].
Lancet Neurology
, 18
(1)
pp. 107-116.
10.1016/S1474-4422(18)30368-5.
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Muliaditan, M;
Della Pasqua, O;
(2019)
How long will treatment guidelines for TB continue to overlook variability in drug exposure?
Journal of Antimicrobial Chemotherapy
, 74
(11)
pp. 3274-3280.
10.1093/jac/dkz319.
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Outeiro, TF;
Harvey, K;
Dominguez-Meijide, A;
Gerhardt, E;
(2019)
LRRK2, alpha-synuclein, and tau: partners in crime or unfortunate bystanders?
Biochemical Society Transactions
, 47
(3)
pp. 827-838.
10.1042/BST20180466.
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Petrache, AL;
Rajulawalla, A;
Shi, A;
Wetzel, A;
Saito, T;
Saido, TC;
Harvey, K;
(2019)
Aberrant Excitatory–Inhibitory Synaptic Mechanisms in Entorhinal Cortex Microcircuits During the Pathogenesis of Alzheimer’s Disease.
Cerebral Cortex
, 29
(4)
pp. 1834-1850.
10.1093/cercor/bhz016.
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Raffaele, F;
Claudia, M;
John, H;
(2019)
Genetics and molecular mechanisms of frontotemporal lobar degeneration: an update and future avenues.
Neurobiology of Aging
, 78
pp. 98-110.
10.1016/j.neurobiolaging.2019.02.006.
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Ruiz, AJ;
Rahim, AA;
(2019)
Bringing balance to the force-regulatable gene therapy for epilepsy.
[Editorial comment].
Gene Therapy
, 26
pp. 347-349.
10.1038/s41434-019-0083-6.
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Santiago-Toledo, G;
Georgiou, M;
Dos Reis, J;
Roberton, VH;
Valinhas, A;
Wood, RC;
Phillips, JB;
... Wall, IB; + view all
(2019)
Generation of c-MycERTAM-transduced human late-adherent olfactory mucosa cells for potential regenerative applications.
Scientific Reports
, 9
(1)
, Article 13190. 10.1038/s41598-019-49315-6.
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Shah, MM;
Martinello, K;
Giacalone, E;
Migliore, M;
Brown, D;
(2019)
The subthreshold-active KV7 current regulates neurotransmission by limiting spike-induced Ca2+ influx in hippocampal mossy fiber synaptic terminals.
Communications Biology
, 2
, Article 145. 10.1038/s42003-019-0408-4.
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Snowball, A;
Chabrol, E;
Wykes, RC;
Shekh-Ahmad, T;
Cornford, JH;
Lieb, A;
Hughes, MP;
... Schorge, S; + view all
(2019)
Epilepsy Gene Therapy Using an Engineered Potassium Channel.
Journal of Neuroscience
, 39
(16)
pp. 3159-3169.
10.1523/JNEUROSCI.1143-18.2019.
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Taylor, A;
Vendramin, C;
Oosterholt, S;
Della Pasqua, O;
Scully, M;
(2019)
Pharmacokinetics of plasma infusion in congenital thrombotic thrombocytopenic purpura.
Journal of Thrombosis and Haemostasis
, 17
(1)
pp. 88-98.
10.1111/jth.14345.
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van Dijkman, SC;
De Cock, PAJG;
Smets, K;
Decaluwe, W;
Smits, A;
Allegaert, K;
Vande Walle, J;
... Della Pasqua, O; + view all
(2019)
Dose rationale and pharmacokinetics of dexmedetomidine in mechanically ventilated new-borns: impact of design optimisation.
European Journal of Clinical Pharmacology
, 75
pp. 1393-1404.
10.1007/s00228-019-02708-y.
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Wicox, M;
Quick, TJ;
Phillips, JB;
(2019)
The Effects of Surgical Antiseptics and Time Delays on RNA Isolated From Human and Rodent Peripheral Nerves.
Frontiers in Cellular Neuroscience
, 13
, Article 189. 10.3389/fncel.2019.00189.
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Conference item
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Bhangra, K;
Knowles, J;
Shipley, R;
Choi, D;
Phillips, J;
(2019)
Serum-free cryopreservation of engineered neural tissue.
Presented at: TCES-UKSB, Nottingham.
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Bhangra, K;
Plotczyk, M;
Knowles, J;
Shipley, R;
Choi, D;
Phillips, J;
(2019)
The Effect of Hypoxia on the Ability of Differentiated Human Dental Pulp Stem Cells to Promote Endothelial Cell Proliferation and Neurite Outgrowth In Vitro.
Presented at: 5th International Symposium of Peripheral Nerve Regeneration (ISPNR 2019), Porto, Portugal.
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Tchorek-Bentall, M;
Ruiz, YO;
Oosterholt, S;
Marks, DJ;
Pasqua, OD;
(2019)
Model-based optimisation of N-acetylcysteine for the treatment of paracetamol overdose.
Presented at: British-Pharmacology-Society Meeting (Pharmacology), London, UK.
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Topczewska, A;
Evans, T;
Pratt, W;
Burgess, N;
Dolphin, A;
Shah, M;
(2019)
T-Type Ca2+ Channels and Layer II Medial Entorhinal Cortical Stellate Cell Excitability.
Presented at: American Biophysics Society Annual Meeting 2019, Baltimore, MD, USA.
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Thesis
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Santiago Toledo, Gerardo;
(2019)
Development of a xeno-free cell culture platform for novel candidate human cell therapies for neural regeneration.
Doctoral thesis (Ph.D), UCL (University College London).
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