Singh, R;
Mackay, AJ;
Patel, AR;
Garcha, DS;
Kowlessar, BS;
Brill, SE;
Donnelly, LE;
... Wedzicha, JA; + view all
(2014)
Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease.
Respir Res
, 15
, Article 114. 10.1186/s12931-014-0114-1.
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Abstract
There has been increasing interest in the use of newer, culture-independent techniques to study the airway microbiome of COPD patients. We investigated the relationships between the three common potentially pathogenic microorganisms (PPMs) Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis, as detected by quantitative PCR (qPCR), and inflammation and health status in stable patients in the London COPD cohort.
| Type: | Article |
|---|---|
| Title: | Inflammatory thresholds and the species-specific effects of colonising bacteria in stable chronic obstructive pulmonary disease. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/s12931-014-0114-1 |
| Publisher version: | http://dx.doi.org/10.1186/s12931-014-0114-1 |
| Language: | English |
| Additional information: | © 2014 Singh et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| Keywords: | Aged, Aged, 80 and over, Cohort Studies, Colony Count, Microbial, Female, Haemophilus influenzae, Humans, Inflammation, Male, Middle Aged, Moraxella (Branhamella) catarrhalis, Prospective Studies, Pulmonary Disease, Chronic Obstructive, Species Specificity, Streptococcus pneumoniae |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1452604 |
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