Magdalinou, N;
Lees, AJ;
Zetterberg, H;
(2014)
Cerebrospinal fluid biomarkers in parkinsonian conditions: an update and future directions.
Journal of Neurology, Neurosurgery & Psychiatry
, 85
(10)
pp. 1065-1075.
10.1136/jnnp-2013-307539.
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Abstract
Parkinsonian diseases comprise a heterogeneous group of neurodegenerative disorders, which show significant clinical and pathological overlap. Accurate diagnosis still largely relies on clinical acumen; pathological diagnosis remains the gold standard. There is an urgent need for biomarkers to diagnose parkinsonian disorders, particularly in the early stages when diagnosis is most difficult. In this review, several of the most promising cerebrospinal fluid candidate markers will be discussed. Their strengths and limitations will be considered together with future developments in the field.
| Type: | Article |
|---|---|
| Title: | Cerebrospinal fluid biomarkers in parkinsonian conditions: an update and future directions |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1136/jnnp-2013-307539 |
| Publisher version: | http://dx.doi.org/10.1136/jnnp-2013-307539 |
| Language: | English |
| Additional information: | This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/ |
| Keywords: | CSF, Corticobasal Degeneration, Multiple System Atrophy, Parkinson's Disease, Progressive Supranuclear Palsy |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neurodegenerative Diseases |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1426989 |
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