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Towards Affordable Smartphone Eye Tracking for Nystagmus Analysis and Monitoring

Duvieusart, Benjamin; Xochicale, Miguel; Kaski, Diego; Leung, Terence S; (2025) Towards Affordable Smartphone Eye Tracking for Nystagmus Analysis and Monitoring. In: Proceedings of the 2025 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE: Copenhagen, Denmark. Green open access

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Abstract

Nystagmus, an involuntary oscillatory eye movement, is an important diagnostic marker for various neurological and vestibular disorders. However, current clinical eye tracking systems are expensive, require specialized equipment and training, thus limiting their usability at scale. This study proposes a smartphone-based eye tracking pipeline for nystagmus analysis, utilizing a deep learning-based segmentation model and a circle-fitting algorithm to estimate pupil position. Two variations of U-Net segmentation models - a 3-class (sclera, iris, background) and a 4-class (sclera, iris, pupil, background) U-Net - were trained on publicly available MOBIUS dataset. Then applied and evaluated on 12 optokinetic nystagmus (OKN) videos with varying gaze positions. On the test set the 3-class model performed best across cross entropy loss, intersection over union loss, and DICE score metrics (0.051, 0.081, and 0.956 respectively), compared to the 4-class model's 0.068, 0.162, and 0.903 respectively. On the tracking task, when evaluated against ground truth tracking measured using the ICS Impulse, both methods were able to capture the nystagmus movements reasonably well (avg R2 of 0.755 and 0.768 for 3 and 4-class methods across 12 OKN tests). No statistical difference in the performance of the 3-class model compared to the 4-class model on R2 (p-value 0.80). These findings highlight the potential of smartphone-based eye tracking as a cost-effective tool for objective nystagmus assessment, with further refinements needed to improve tracking performance. This approach could enhance diagnostic accuracy and accessibility in clinical settings.

Type: Proceedings paper
Title: Towards Affordable Smartphone Eye Tracking for Nystagmus Analysis and Monitoring
Event: 2025 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Location: United States
Dates: 14 Jul 2025 - 18 Jul 2025
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/EMBC58623.2025.11253718
Publisher version: https://doi.org/10.1109/EMBC58623.2025.11253718
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Training, Iris, Tracking, Pipelines, Gaze tracking, Medical services, Software, Pupils, Usability, Videos
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10221365
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