Khan, Abbas; Asad, Muhammad; Benning, Martin; Roney, Caroline; Slabaugh, Gregory; (2025) CAMS: Convolution and Attention-Free Mamba-based Cardiac Image Segmentation. In: 2025 IEEE/CVF Winter Conference on Applications of Computer Vision (WACV). (pp. pp. 1893-1903). IEEE: Tucson, AZ, USA.

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Abstract

Convolutional Neural Networks (CNNs) and Transformer-based self-attention models have become the standard for medical image segmentation. This paper demonstrates that convolution and self-attention, while widely used, are not the only effective methods for segmentation. Breaking with convention, we present a Convolution and self-Attention-free Mamba-based seman-tic Segmentation Network named CAMS-Net. Specifically, we design Mamba-based Channel Aggregator and Spatial Aggregator, which are applied independently in each encoder-decoder stage. The Channel Aggregator extracts information across different channels, and the Spatial Ag-gregator learns features across different spatial locations. We also propose a Linearly Interconnected Factorized Mamba (LIFM) block to reduce the computational complexity of a Mamba block and to enhance its decision function by introducing a non-linearity between two factor-ized Mamba blocks. Our model outperforms the existing state-of-the-art CNN, self-attention, and Mamba-based methods on CMR and M&Ms-2 Cardiac segmentation datasets, showing how this innovative, convolution, and self-attention-free method can inspire further research beyond CNN and Transformer paradigms, achieving linear complexity and reducing the number of parameters. Source code and pre-trained models are available at: https://github.com/kabbas570/CAMS-Net.

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