Son, Yujeong;
Kim, Han-Sung;
Lee, Ju-Hyeon;
Jang, Jisun;
Lee, Chin-Fa;
Lee, Sunwoo;
(2017)
Nickel-catalyzed decarboxylative coupling of an alkynyl carboxylic acid with aryl iodides.
Tetrahedron Letters
, 58
(14)
pp. 1413-1416.
10.1016/j.tetlet.2017.02.073.
Preview |
Text
son2017.pdf - Published Version Download (381kB) | Preview |
Abstract
A decarboxylative coupling reaction with an alkynyl carboxylic acid and aryl iodides in the presence of a nickel catalyst was developed. When the reaction was conducted with NiCl2 (10 mol%), Xantphos (15 mol%), Mn (1.0 equiv), and Cs2CO3 (1.5 equiv), the desired diaryl alkynes were formed in moderated to good yields. Furthermore, this method does not produce the diyne, which is formed in the homocoupling of alkynyl carboxylic acids.
| Type: | Article |
|---|---|
| Title: | Nickel-catalyzed decarboxylative coupling of an alkynyl carboxylic acid with aryl iodides |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.tetlet.2017.02.073 |
| Publisher version: | http://dx.doi.org/10.1016/j.tetlet.2017.02.073 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Nickel; Decarboxylative coupling; Alkynyl carboxylic acid; Aryl iodide; Reductant |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL SLASH UCL > Provost and Vice Provost Offices > UCL SLASH > Faculty of S&HS UCL > Provost and Vice Provost Offices > UCL SLASH > Faculty of S&HS > Institute of Archaeology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10200177 |
Archive Staff Only
 |
View Item |
