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A perspective on brain-age estimation and its clinical promise

Gaser, Christian; Kalc, Polona; Cole, James H; (2024) A perspective on brain-age estimation and its clinical promise. Nature Computational Science , 4 pp. 744-751. 10.1038/s43588-024-00659-8. Green open access

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Abstract

Brain-age estimation has gained increased attention in the neuroscientific community owing to its potential use as a biomarker of brain health. The difference between estimated and chronological age based on neuroimaging data enables a unique perspective on brain development and aging, with multiple open questions still remaining in the brain-age research field. This Perspective presents an overview of current advancements in the field and envisions the future evolution of the brain-age framework before its potential deployment in hospital settings.

Type: Article
Title: A perspective on brain-age estimation and its clinical promise
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1038/s43588-024-00659-8
Publisher version: https://doi.org/10.1038/s43588-024-00659-8
Language: English
Additional information: This version is the author-accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Diagnostic markers, Learning algorithms
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
URI: https://discovery.ucl.ac.uk/id/eprint/10197493
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