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Single-exposure X-ray phase imaging microscopy with a grating interferometer

Wolf, Andreas; Akstaller, Bernhard; Cipiccia, Silvia; Flenner, Silja; Hagemann, Johannes; Ludwig, Veronika; Meyer, Pascal; ... Funk, Stefan; + view all (2022) Single-exposure X-ray phase imaging microscopy with a grating interferometer. Journal of Synchrotron Radiation , 29 (Pt 3) pp. 794-806. 10.1107/S160057752200193X. Green open access

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Abstract

The advent of hard X-ray free-electron lasers enables nanoscopic X-ray imaging with sub-picosecond temporal resolution. X-ray grating interferometry offers a phase-sensitive full-field imaging technique where the phase retrieval can be carried out from a single exposure alone. Thus, the method is attractive for imaging applications at X-ray free-electron lasers where intrinsic pulse-to-pulse fluctuations pose a major challenge. In this work, the single-exposure phase imaging capabilities of grating interferometry are characterized by an implementation at the I13-1 beamline of Diamond Light Source (Oxfordshire, UK). For comparison purposes, propagation-based phase contrast imaging was also performed at the same instrument. The characterization is carried out in terms of the quantitativeness and the contrast-to-noise ratio of the phase reconstructions as well as via the achievable spatial resolution. By using a statistical image reconstruction scheme, previous limitations of grating interferometry regarding the spatial resolution can be mitigated as well as the experimental applicability of the technique.

Type: Article
Title: Single-exposure X-ray phase imaging microscopy with a grating interferometer
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1107/S160057752200193X
Publisher version: https://doi.org/10.1107/S160057752200193X
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Technology, Physical Sciences, Instruments & Instrumentation, Optics, Physics, Applied, Physics, phase contrast X-ray imaging, X-ray microscopy, grating interferometry, phase retrieval, FREE-ELECTRON LASER, WAVE-FRONT, CONTRAST, RESOLUTION, TOMOGRAPHY, TOPOGRAPHY
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10151740
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