Li, Tongtong;
Zheng, Yu;
Wang, Zhe;
Zhu, David C;
Ren, Jian;
Liu, Taosheng S;
Friston, Karl;
(2022)
Brain information processing capacity modeling.
Scientific Reports
, 12
(1)
, Article 2174. 10.1038/s41598-022-05870-z.
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Abstract
Neurophysiological measurements suggest that human information processing is evinced by neuronal activity. However, the quantitative relationship between the activity of a brain region and its information processing capacity remains unclear. We introduce and validate a mathematical model of the information processing capacity of a brain region in terms of neuronal activity, input storage capacity, and the arrival rate of afferent information. We applied the model to fMRI data obtained from a flanker paradigm in young and old subjects. Our analysis showed that-for a given cognitive task and subject-higher information processing capacity leads to lower neuronal activity and faster responses. Crucially, processing capacity-as estimated from fMRI data-predicted task and age-related differences in reaction times, speaking to the model's predictive validity. This model offers a framework for modelling of brain dynamics in terms of information processing capacity, and may be exploited for studies of predictive coding and Bayes-optimal decision-making.
| Type: | Article |
|---|---|
| Title: | Brain information processing capacity modeling |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1038/s41598-022-05870-z |
| Publisher version: | https://doi.org/10.1038/s41598-022-05870-z |
| Language: | English |
| Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third-party material in this article are included in the Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
| Keywords: | Engineering, Neuroscience |
| UCL classification: | UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10143782 |
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