Mollero, R;
Delingette, H;
Datar, M;
Heimann, T;
Hauser, JA;
Panesar, D;
Jones, A;
... Sermesant, M; + view all
(2017)
Longitudinal Analysis Using Personalised 3D Cardiac Models with Population-Based Priors: Application to Paediatric Cardiomyopathies.
In: Descoteaux, M and Maier-Hein, L and Franz, A and Jannin, P and Collins, D L, (eds.)
Medical Image Computing and Computer-Assisted Intervention − MICCAI 2017.
(pp. pp. 350-358).
Springer: Cham, Switzerland.
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Abstract
Personalised 3D modelling of the heart is of increasing interest in order to better characterise pathologies and predict evolution. The personalisation consists in estimating the parameter values of an electromechanical model in order to reproduce the observed cardiac motion. However, the number of parameters in these models can be high and their estimation may not be unique. This variability can be an obstacle to further analyse the estimated parameters and for their clinical interpretation. In this paper we present a method to perform consistent estimations of electromechanical parameters with prior probabilities on the estimated values, which we apply on a large database of 84 different heartbeats. We show that the use of priors reduces considerably the variance in the estimated parameters, enabling better conditioning of the parameters for further analysis of the cardiac function. This is demonstrated by the application to longitudinal data of paediatric cardiomyopathies, where the estimated parameters provide additional information on the pathology and its evolution.
| Type: | Proceedings paper |
|---|---|
| Title: | Longitudinal Analysis Using Personalised 3D Cardiac Models with Population-Based Priors: Application to Paediatric Cardiomyopathies |
| Event: | 20th International Conference, Quebec City, QC, Canada, September 11-13, 2017, Proceedings, Part II |
| ISBN-13: | 9783319661841 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/978-3-319-66185-8_40 |
| Publisher version: | https://doi.org/10.1007/978-3-319-66185-8_40 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Childrens Cardiovascular Disease |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10092540 |
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