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Necrotising Enterocolitis

Hall, NJ; Eaton, S; Pierro, A; (2018) Necrotising Enterocolitis. In: Losty, PD and Flake, AW and Rintala, RJ and Hutson, JM and Iwai, N, (eds.) Rickham's Neonatal Surgery. (pp. 777-787). Springer: London, UK. Green open access

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Abstract

Necrotising enterocolitis (NEC) is a devastating disease of infants and the commonest gastrointestinal emergency in the newborn period. It is a condition characterised by intestinal necrosis affecting the ileum and/or colon. There is a wide spectrum of clinical manifestations. In the least severe cases there may be mild inflammation of the intestinal wall in a baby with mild abdominal distension and minimal systemic upset. The most severely affected cases, however, may show evidence of full thickness intestinal necrosis with perforation, respiratory and cardiovascular collapse, multi-system organ failure and in some cases death.

Type: Book chapter
Title: Necrotising Enterocolitis
ISBN: 1447147219
ISBN-13: 9781447147213
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-1-4471-4721-3_38
Publisher version: https://doi.org/10.1007/978-1-4471-4721-3_38
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Necrotising enterocolitis (NEC), Bell’s classification, Staging, Peritoneal drainage, Surgery, Stomas, RCTs
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/10053779
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