Browse by UCL people
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Number of items: 82.
Article
Adriano Vieira, Vinicius;
Lim, Nicholas;
Singh, Alveera;
Leitman, Ellen;
D'Souza, Reena R;
Adland, Emily;
Muenchhoff, Maximilian;
... Goulder, Philip; + view all
(2023)
Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype.
JCI Insight
, 8
(3)
, Article e156049.. 10.1172/jci.insight.156049.
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Ardain, A;
Domingo-Gonzalez, R;
Das, S;
Kazer, SW;
Howard, NC;
Singh, A;
Ahmed, M;
... Khader, SA; + view all
(2019)
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Nature
, 570
(7762)
pp. 528-532.
10.1038/s41586-019-1276-2.
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Attaf, Meriem;
Roider, Julia;
Malik, Amna;
Rafael, Cristina Rius;
Dolton, Garry;
Prendergast, Andrew J;
Leslie, Alasdair;
... Goulder, Philip J; + view all
(2020)
Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life (vol 11, 1587, 2020).
[Corrigendum].
Frontiers in Immunology
, 11
, Article 633633. 10.3389/fimmu.2020.633633.
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Attaf, M;
Malik, A;
Severinsen, MC;
Roider, J;
Ogongo, P;
Buus, S;
Ndung'u, T;
... Goulder, P; + view all
(2018)
Major TCR Repertoire Perturbation by Immunodominant HLA-B*44:03-Restricted CMV-Specific T Cells.
Frontiers in Immunology
, 9
, Article 2539. 10.3389/fimmu.2018.02539.
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Attaf, M;
Roider, J;
Malik, A;
Rius Rafael, C;
Dolton, G;
Predergast, AJ;
Leslie, A;
... Goulder, PJ; + view all
(2020)
Cytomegalovirus-Mediated T Cell Receptor Repertoire Perturbation Is Present in Early Life.
Frontiers in Immunology
, 11
, Article 1587. 10.3389/fimmu.2020.01587.
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Baiyegunhi, OO;
Mann, J;
Khaba, T;
Nkosi, T;
Mbatha, A;
Ogunshola, F;
Chasara, C;
... Ndhlovu, ZM; + view all
(2022)
CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection.
Nature communications
, 13
, Article 4041. 10.1038/s41467-022-31692-8.
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Bloom, SM;
Mafunda, NA;
Woolston, BM;
Hayward, MR;
Frempong, JF;
Abai, AB;
Xu, J;
... Kwon, DS; + view all
(2022)
Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation.
Nature Microbiology
, 7
pp. 434-450.
10.1038/s41564-022-01070-7.
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Byrne, Elizabeth H;
Farcasanu, Mara;
Bloom, Seth M;
Xulu, Nondumiso;
Xu, Jiawu;
Hykes, Barry L;
Mafunda, Nomfuneko A;
... Kwon, Douglas S; + view all
(2021)
Antigen Presenting Cells Link the Female Genital Tract Microbiome to Mucosal Inflammation, With Hormonal Contraception as an Additional Modulator of Inflammatory Signatures.
Frontiers in Cellular and Infection Microbiology
, 11
, Article 733619. 10.3389/fcimb.2021.733619.
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Delphin, Marion;
Mohammed, Khadija Said;
Downs, Louise O;
Lumley, Sheila F;
Waddilove, Elizabeth;
Okanda, Dorcas;
Aliyan, Nadia;
... Taljaard, Jantjie; + view all
(2024)
Under-representation of the WHO African region in clinical trials of interventions against hepatitis B virus infection.
The Lancet Gastroenterology & Hepatology
, 9
(4)
pp. 383-392.
10.1016/S2468-1253(23)00315-1.
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Dube, Karine;
Mthimkhulu, Deli;
Ngcobo, Wiseman;
Mindry, Deborah;
Maphalala, Luyanda;
Pillay, Vanessa;
Tran, Whitney;
... Dong, Krista; + view all
(2023)
'With this study, we have hope that something is coming': community members' perceptions of HIV cure-related research in Durban, South Africa - a qualitative focus group study.
HIV Research & Clinical Practice
, 24
(1)
, Article 2243046. 10.1080/25787489.2023.2243046.
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Dybul, M;
Attoye, T;
Baptiste, S;
Cherutich, P;
Dabis, F;
Deeks, SG;
Dieffenbach, C;
... Sunnylands 2019 Working Group; + view all
(2021)
The case for an HIV cure and how to get there.
The Lancet HIV
, 8
(1)
e51-e58.
10.1016/S2352-3018(20)30232-0.
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Fakey Khan, D;
Suleman, M;
Baijnath, P;
Perumal, R;
Moodley, V;
Mhlane, Z;
Naidoo, T;
... Wong, EB; + view all
(2019)
Multiple microbiologic tests for tuberculosis improve diagnostic yield of bronchoscopy in medically complex patients [version 1; peer review: 2 approved].
AAS Open Research
, 2
, Article 25. 10.12688/aasopenres.12980.1.
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Farinre, O;
Gounder, K;
Reddy, T;
Tongo, M;
Hare, J;
Chaplin, B;
Gilmour, J;
... Ndung'u, T; + view all
(2021)
Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa.
Retrovirology
, 18
(1)
, Article 11. 10.1186/s12977-021-00554-4.
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Fehr, J;
Gunda, R;
Siedner, MJ;
Hanekom, W;
Ndung'u, T;
Grant, A;
Lippert, C;
(2023)
CAD4TB software updates: different triaging thresholds require caution by users and regulation by authorities.
The International Journal of Tuberculosis and Lung Disease
, 27
(2)
pp. 157-160.
10.5588/ijtld.22.0437.
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Fwambah, Lynn;
Andisi, Cheryl;
Streatfield, Claire;
Bromell, Rachel;
Hare, Jonathan;
Esbjoernsson, Joakim;
Ndung'u, Thumbi;
... Nduati, Eunice; + view all
(2024)
Exposure to common infections may shape basal immunity and potentially HIV-1 acquisition amongst a high-risk population in Coastal Kenya.
Frontiers in Immunology
, 14
, Article 1283559. 10.3389/fimmu.2023.1283559.
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Graham, SM;
Agutu, C;
van der Elst, E;
Hassan, AS;
Gichuru, E;
Mugo, PM;
Farquhar, C;
... Sanders, EJ; + view all
(2020)
A Novel HIV-1 RNA Testing Intervention to Detect Acute and Prevalent HIV Infection in Young Adults and Reduce HIV Transmission in Kenya: Protocol for a Randomized Controlled Trial.
JMIR Research Protocols
, 9
(8)
, Article e16198. 10.2196/16198.
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Hassan, AS;
Hare, J;
Gounder, K;
Nazziwa, J;
Karlson, S;
Olsson, L;
Streatfield, C;
... Sanders, EJ; + view all
(2021)
A Stronger Innate Immune Response During Hyperacute Human Immunodeficiency Virus Type 1 (HIV-1) Infection Is Associated With Acute Retroviral Syndrome.
Clinical Infectious Diseases
, 73
(5)
pp. 832-841.
10.1093/cid/ciab139.
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Hwa, Shi-Hsia;
Snyman, Jumari;
Bernstein, Mallory;
Ganga, Yashica;
Cele, Sandile;
Muema, Daniel;
Tan, Chee Wah;
... Sigal, Alex; + view all
(2022)
Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant.
Journal of Infectious Diseases
, 227
(2)
pp. 211-220.
10.1093/infdis/jiac343.
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Jeewanraj, N;
Mandizvo, T;
Mulaudzi, T;
Gumede, N;
Ndhlovu, Z;
Ndung'u, T;
Gounder, K;
(2023)
Partial compartmentalisation of HIV-1 subtype C between lymph nodes, peripheral blood mononuclear cells and plasma.
Virology
, 582
pp. 62-70.
10.1016/j.virol.2023.03.011.
(In press).
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Jennewein, MF;
Mabuka, J;
Papia, CL;
Boudreau, CM;
Dong, KL;
Ackerman, ME;
Ndung'u, T;
(2020)
Tracking the Trajectory of Functional Humoral Immune Responses Following Acute HIV Infection.
Frontiers in Immunology
, 11
, Article 1744. 10.3389/fimmu.2020.01744.
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Jin, SW;
Mwimanzi, FM;
Mann, JK;
Bwana, MB;
Lee, GQ;
Brumme, CJ;
Hunt, PW;
... Brockman, MA; + view all
(2020)
Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5.
PLOS Pathogens
, 16
(9)
, Article e1008813. 10.1371/journal.ppat.1008813.
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Karim, F;
Gazy, I;
Cele, S;
Zungu, Y;
Krause, R;
Bernstein, M;
Khan, K;
... Sigal, A; + view all
(2021)
HIV status alters disease severity and immune cell responses in beta variant SARS-CoV-2 infection wave.
eLife
, 10
, Article e67397. 10.7554/eLife.67397.
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Kasprowicz, Victoria O;
Jeffery, Caroline;
Mbuvi, Dorcas;
Bukirwa, Victoria;
Ouattara, Karim;
Kirimi, Florence;
Heitz-Tokpa, Kathrin;
... Ndung'u, Thumbi; + view all
(2023)
How to improve research capacity strengthening efforts: learning from the monitoring and evaluation of four research consortia in Africa.
Health Research Policy and Systems
, 21
, Article 109. 10.1186/s12961-023-01056-9.
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Kasprowicz, Victoria O;
Waddilove, Kim Darley;
Chopera, Denis;
Khumalo, Sipho;
Harilall, Sashin;
Wong, Emily B;
Karita, Etienne;
... Ndung'u, Thumbi; + view all
(2023)
Developing a diversity, equity and inclusion compass to guide scientific capacity strengthening efforts in Africa.
PLOS Global Public Health
, 3
(12)
, Article e0002339. 10.1371/journal.pgph.0002339.
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Kasprowicz, VO;
Chopera, D;
Waddilove, KD;
Brockman, MA;
Gilmour, J;
Hunter, E;
Kilembe, W;
... Ndung'u, T; + view all
(2020)
African-led health research and capacity building- is it working?
BMC Public Health
, 20
(1)
, Article 1104. 10.1186/s12889-020-08875-3.
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Kazer, SW;
Aicher, TP;
Muema, DM;
Carroll, SL;
Ordovas-Montanes, J;
Miao, VN;
Tu, AA;
... Shalek, AK; + view all
(2020)
Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection.
Nature Medicine
, 26
pp. 511-518.
10.1038/s41591-020-0799-2.
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Khuzwayo, Sharon;
Mthembu, Maphe;
Meermeier, Erin W;
Prakadan, Sanjay M;
Kazer, Samuel W;
Bassett, Thierry;
Nyamande, Kennedy;
... Wong, Emily B; + view all
(2021)
MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection.
Frontiers in Immunology
, 12
, Article 631410. 10.3389/fimmu.2021.631410.
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Kinyanjui, S;
Fonn, S;
Kyobutungi, C;
Vicente-Crespo, M;
Bonfoh, B;
Ndungu, T;
Sewankambo, NK;
... Awandare, G; + view all
(2020)
Enhancing science preparedness for health emergencies in Africa through research capacity building.
BMJ Global Health
, 5
(7)
, Article e003072. 10.1136/bmjgh-2020-003072.
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Lewin, SR;
Attoye, T;
Bansbach, C;
Doehle, B;
Dubé, K;
Dybul, M;
SenGupta, D;
... Sunnylands 2019 Working Group; + view all
(2021)
Multi-stakeholder consensus on a target product profile for an HIV cure.
The Lancet HIV
, 8
(1)
e42-e50.
10.1016/S2352-3018(20)30234-4.
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Lustig, Gila;
Ganga, Yashica;
Rodel, Hylton E;
Tegally, Houriiyah;
Khairallah, Afrah;
Jackson, Laurelle;
Cele, Sandile;
... Sigal, Alex; + view all
(2024)
SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations.
Virus Evolution
, 10
(1)
, Article vead075. 10.1093/ve/vead075.
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Luthuli, Bonisile;
Gounder, Kamini;
Deymier, Martin J;
Dong, Krista L;
Balazs, Alejandro B;
Mann, Jaclyn K;
Ndung'u, Thumbi;
(2023)
Generation and characterization of infectious molecular clones of transmitted/founder HIV-1 subtype C viruses.
Virology
, 583
pp. 14-26.
10.1016/j.virol.2023.04.001.
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Madlala, P;
Mkhize, Z;
Naicker, S;
Khathi, SP;
Maikoo, S;
Gopee, K;
Dong, KL;
(2023)
Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes.
PLOS Pathogens
, 19
(6)
, Article e1011194. 10.1371/journal.ppat.1011194.
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Magnoumba, M;
Singh, A;
Ogongo, P;
Roider, J;
Asowata, O;
Fehlings, M;
Karim, F;
... Kløverpris, H; + view all
(2020)
Unbiased Profiling Reveals Compartmentalization of Unconventional T-Cells Within the Intestinal Mucosa Irrespective of HIV Infection.
Frontiers in Immunology
, 11
, Article 579743. 10.3389/fimmu.2020.579743.
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Mandizvo, Tawanda;
Gumede, Nombali;
Ndlovu, Bongiwe;
Ndlovu, Siphiwe;
Mann, Jaclyn K;
Chopera, Denis R;
Singh, Lanish;
... Ndung'u, Thumbi; + view all
(2022)
Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection.
Journal of Virology
, Article e0127022. 10.1128/jvi.01270-22.
(In press).
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Mann, JK;
Ndung'u, T;
(2020)
The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19.
Future Virology
, 15
(9)
pp. 609-624.
10.2217/fvl-2020-0170.
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Mann, JK;
Reddy, T;
Der Stok, MV;
Ngubane, A;
Mulaudzi, T;
Mchunu, N;
Nevhungoni, P;
... Gosnell, BI; + view all
(2023)
Hen egg white bovine colostrum supplement reduces symptoms of mild/moderate COVID-19: a randomized control trial.
Future Science OA
, 9
(8)
, Article FSO882. 10.2144/fsoa-2023-0024.
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Mann, JK;
Rajkoomar, E;
Jin, SW;
Mkhize, Q;
Baiyegunhi, O;
Mbona, P;
Brockman, MA;
(2020)
Consequences of HLA‐associated mutations in HIV‐1 subtype C Nef on HLA‐I downregulation ability.
Journal of Medical Virology
, 92
(8)
pp. 1182-1190.
10.1002/jmv.25676.
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Mdletshe, N;
Thobakgale, C;
Malaba, TR;
Madlala, H;
Myer, L;
Muema, DM;
Mogeni, P;
... Ndung'u, T; + view all
(2021)
Low Immune Activation in Early Pregnancy Is Associated With Preterm But Not Small-for-gestational-age Delivery in Women Infected With Human Immunodeficiency Virus Initiating Antiretroviral Therapy in Pregnancy: A Prematurity Immunology in HIV-infected Mothers and their Infants Study (PIMS) Case-control Study in Cape Town, South Africa.
Clinical Infectious Diseases
, 73
(12)
pp. 2205-2216.
10.1093/cid/ciab151.
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Miall, A;
McLellan, R;
Dong, K;
Ndung'u, T;
Saberi, P;
Sauceda, JA;
Dubé, K;
(2021)
Bringing social context into global biomedical HIV cure-related research: An urgent call to action.
Journal of Virus Eradication
10.1016/j.jve.2021.100062.
(In press).
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Millar, JR;
Bengu, N;
Vieira, VA;
Adland, E;
Roider, J;
Muenchhoff, M;
Fillis, R;
... Goulder, P; + view all
(2021)
Early initiation of antiretroviral therapy following in utero HIV infection is associated with low viral reservoirs but other factors determine subsequent plasma viral rebound.
Journal of Infectious Diseases
, Article jiab223. 10.1093/infdis/jiab223.
(In press).
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Millar, JR;
Fatti, I;
Mchunu, N;
Bengu, N;
Grayson, NE;
Adland, E;
Bonsall, D;
... Goulder, P; + view all
(2021)
Second-generation mother-to-child HIV transmission in South Africa is characterized by poor outcomes.
AIDS
, 35
(10)
pp. 1597-1604.
10.1097/QAD.0000000000002915.
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Millar, JR;
Bengu, N;
Fillis, R;
Sprenger, K;
Ntlantsana, V;
Vieira, VA;
Khambati, N;
... Ucwaningo Lwabantwana Consortium; + view all
(2020)
HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE.
EClinicalMedicine
, 22
, Article 100344. 10.1016/j.eclinm.2020.100344.
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Mlimi, Hlelolwenkosi;
Naidoo, Kewreshini K;
Mabuka, Jenniffer;
Ndung'u, Thumbi;
Madlala, Paradise;
(2022)
Bone marrow stromal antigen 2 (BST-2) genetic variants influence expression levels and disease outcome in HIV-1 chronically infected patients.
Retrovirology
, 19
, Article 3. 10.1186/s12977-022-00588-2.
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Moyano, Ana;
Ndlovu, Bongiwe;
Mbele, Msizi;
Naidoo, Kewreshini;
Khan, Nasreen;
Mann, Jaclyn K;
Ndung'u, Thumbi;
(2023)
Differing natural killer cell, T cell and antibody profiles in antiretroviral-naive HIV-1 viraemic controllers with and without protective HLA alleles.
PLoS One
, 18
(6)
, Article e0286507. 10.1371/journal.pone.0286507.
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Moyano, Ana;
Ndung'u, Thumbi;
Mann, Jaclyn K;
(2021)
Determinants of natural HIV-1 control.
AIDS Reviews
, 24
(2)
10.24875/AIDSRev.21000048.
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Mthembu, M;
Bowman, KA;
Davies, LRL;
Khuzwayo, S;
Mazibuko, L;
Bassett, T;
Ramjit, D;
... Wong, EB; + view all
(2023)
Discrepancy between Mtb-specific IFN-γ and IgG responses in HIV-positive people with low CD4 counts.
eBioMedicine
, 90
, Article 104504. 10.1016/j.ebiom.2023.104504.
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Mthembu, Maphe;
Baiyegunhi, Omolara;
Mdleleni, Yanga;
Ndlovu, Lerato;
Keal, Hannah;
Waddilove, Kim;
Yarrow, Justin C;
... Wong, Emily B; + view all
(2023)
A PowerPack of SuperScientists: An innovative concept by African scientists to address gender bias and inequity in science [version 2; peer review: 1 approved, 1 approved with reservations].
Wellcome Open Research
, 7
, Article 87. 10.12688/wellcomeopenres.17668.2.
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Muema, DM;
Akilimali, NA;
Ndumnego, OC;
Rasehlo, SS;
Durgiah, R;
Ojwach, DBA;
Ismail, N;
... Ndung'u, T; + view all
(2020)
Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection.
BMC Medicine
, 18
, Article 81. 10.1186/s12916-020-01529-6.
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Muema, DM;
Mthembu, M;
Schiff, AE;
Singh, U;
Corleis, B;
Chen, D;
Bassett, T;
... Wong, EB; + view all
(2020)
Contrasting Inflammatory Signatures in Peripheral Blood and Bronchoalveolar Cells Reveal Compartment-Specific Effects of HIV Infection.
Frontiers In Immunology
, 11
, Article 864. 10.3389/fimmu.2020.00864.
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Muenchhoff, M;
Adland, E;
Roider, J;
Kløverpris, H;
Leslie, A;
Boehm, S;
Keppler, OT;
... Goulder, PJR; + view all
(2019)
Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children.
The Journal of infectious diseases
, 219
(9)
pp. 1407-1417.
10.1093/infdis/jiy668.
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Muenchhoff, M;
Healy, M;
Singh, R;
Roider, J;
Groll, A;
Kindra, C;
Sibaya, T;
... Archary, M; + view all
(2018)
Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy.
AIDS Research and Human Retroviruses
, 34
(1)
pp. 46-55.
10.1089/AID.2016.0261.
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Munoz, Alexander;
Hayward, Matthew R;
Bloom, Seth M;
Rocafort, Muntsa;
Ngcapu, Sinaye;
Mafunda, Nomfuneko A;
Xu, Jiawu;
... Kwon, Douglas S; + view all
(2021)
Modeling the temporal dynamics of cervicovaginal microbiota identifies targets that may promote reproductive health.
Microbiome
, 9
, Article 163. 10.1186/s40168-021-01096-9.
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Munoz, Alexander;
Hayward, Matthew R;
Bloom, Seth M;
Rocafort, Muntsa;
Ngcapu, Sinaye;
Mafunda, Nomfuneko A;
Xu, Jiawu;
... Kwon, Douglas S; + view all
(2021)
Modeling the temporal dynamics of cervicovaginal microbiota identifies targets that may promote reproductive health (vol 9, 163, 2021).
[Corrigendum].
Microbiome
, 9
, Article 206. 10.1186/s40168-021-01171-1.
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Mwimanzi, F;
Ngare, I;
Toyoda, M;
Mori, M;
Mann, J;
Ndung'u, T;
Goulder, P;
(2020)
An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles.
AIDS
, 34
(9)
pp. 1325-1330.
10.1097/QAD.0000000000002559.
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Naicker, Delon;
Sonela, Nelson;
Jin, Steven W.;
Mulaudzi, Takalani;
Ojwach, Doty;
Reddy, Tarylee;
Brockman, Mark A.;
... Mann, Jaclyn K; + view all
(2023)
HIV-1 subtype C Nef-mediated SERINC5 down-regulation significantly contributes to overall Nef activity.
Retrovirology
, 20
, Article 3. 10.1186/s12977-023-00618-7.
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Naidoo, Kewreshini K;
Highton, Andrew J;
Baiyegunhi, Omolara O;
Bhengu, Sindiswa P;
Dong, Krista L;
Bunders, Madeleine J;
Altfeld, Marcus;
(2023)
Early Initiation of Antiretroviral Therapy Preserves the Metabolic Function of CD4+ T Cells in Subtype C Human Immunodeficiency Virus 1 Infection.
The Journal of Infectious Diseases
, Article jiad432. 10.1093/infdis/jiad432.
(In press).
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Naidoo, Kewreshini K;
Ndumnego, Okechukwu C;
Ismail, Nasreen;
Dong, Krista L;
Ndung'u, Thumbi;
(2021)
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