Browse by UCL people
Group by: Type | Date
Number of items: 19.
2025
McKibben, Lauren A;
Iyer, Meghna;
Zhao, Ying;
Florea, Roxana;
Kuhl-Chimera, Sophia;
Deliwala, Ishani;
Pan, Yue;
... Linnstaedt, Sarah D; + view all
(2025)
Transcriptional changes across tissue and time provide molecular insights into a therapeutic window of opportunity following traumatic stress exposure.
Translational Psychiatry
, 15
(1)
, Article 244. 10.1038/s41398-025-03451-y.
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Morgan, Oakley B;
Singleton, Samuel;
Florea, Roxana;
Hestehave, Sara;
Sarter, Tim;
Wozniak, Eva;
Mein, Charles A;
... Géranton, Sandrine M; + view all
(2025)
Stress, epigenetic remodeling and FKBP51: Pathways to chronic pain vulnerability.
Brain, Behavior, and Immunity
, 130
, Article 106119. 10.1016/j.bbi.2025.106119.
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2024
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Hestehave, Sara;
Florea, Roxana;
Fedorec, Alexander JH;
Jevic, Maria;
Mercy, Lucile;
Wright, Annia;
Morgan, Oakley B;
... Geranton, Sandrine M; + view all
(2024)
Differences in multidimensional phenotype of 2 joint pain models link early weight-bearing deficit to late depressive-like behavior in male mice.
Pain Reports
, 9
(6)
, Article e1213. 10.1097/PR9.0000000000001213.
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2023
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Florea, R;
Linnstaedt, SD;
Géranton, SM;
(2023)
Editorial: Mechanisms underlying the interactions between stress and pain.
Frontiers in Pain Research
, 4
, Article 1285257. 10.3389/fpain.2023.1285257.
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Maiarù, Maria;
Acton, Richard J;
Woźniak, Eva L;
Mein, Charles A;
Bell, Christopher G;
Géranton, Sandrine M;
(2023)
A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain.
Clinical Epigenetics
, 15
, Article 155. 10.1186/s13148-023-01569-8.
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2019
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Geranton, S;
(2019)
Does epigenetic ‘memory’ of early-life stress predispose to chronic pain in later life? A potential role for the stress regulator FKBP5.
Philosophical Transactions B: Biological Sciences
, 374
(1785)
, Article 20190283. 10.1098/rstb.2019.0283.
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2018
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Maiarù, M;
Morgan, OB;
Mao, T;
Breitsamer, M;
Bamber, H;
Pöhlmann, M;
Schmidt, MV;
... Géranton, SM; + view all
(2018)
The Stress Regulator Fkbp51: A Novel and Promising Druggable Target for the Treatment of Persistent Pain States Across Sexes.
Pain
, 159
(7)
pp. 1224-1234.
10.1097/j.pain.0000000000001204.
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2016
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Maiarù, M;
Morgan, OB;
Tochiki, KK;
Hobbiger, EJ;
Rajani, K;
Overington, DW;
Géranton, SM;
(2016)
Complex regulation of the regulator of synaptic plasticity histone deacetylase 2 in the rodent dorsal horn after peripheral injury.
Journal of Neurochemistry
, 138
(2)
pp. 222-232.
10.1111/jnc.13621.
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Maiarù, M;
Tochiki, KK;
Cox, MB;
Annan, LV;
Bell, CG;
Feng, X;
Geranton, SM;
(2016)
The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling.
Science Translational Medicine
, 8
(325)
, Article 325ra19. 10.1126/scitranslmed.aab3376.
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Mangione, AS;
Obara, I;
Maiarú, M;
Geranton, SM;
Tassorelli, C;
Ferrari, E;
Leese, C;
... Hunt, SP; + view all
(2016)
Nonparalytic botulinum molecules for the control of pain.
Pain
, 157
(5)
pp. 1045-1055.
10.1097/j.pain.0000000000000478.
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Tochiki, KK;
Maiarú, M;
Norris, C;
Hunt, SP;
Géranton, SM;
(2016)
The mitogen and stress-activated protein kinase 1 regulates the rapid epigenetic tagging of dorsal horn neurons and nocifensive behaviour.
Pain
, 157
(11)
pp. 2594-2604.
10.1097/j.pain.0000000000000679.
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2015
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Obara, IG;
Medrano, CM;
Signoret-Genest, J;
Jiménez-Díaz, L;
Geranton, SM;
Hunt, SP;
(2015)
Inhibition of the Mammalian Target of Rapamycin Complex 1 (mTORC1) signaling pathway reduces itch behaviour in mice.
Pain
, 156
(8)
pp. 1519-1529.
10.1097/j.pain.0000000000000197.
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Tochiki, KK;
Maiarù, M;
Miller, JR;
Hunt, SP;
Géranton, SM;
(2015)
Short-term anesthesia inhibits formalin-induced extracellular signal-regulated kinase (ERK) activation in the rostral anterior cingulate cortex but not in the spinal cord.
Molecular Pain
, 11
, Article 49. 10.1186/s12990-015-0052-z.
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2014
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Carr, FB;
Géranton, SM;
Hunt, SP;
(2014)
Descending controls modulate inflammatory joint pain and regulate CXC chemokine and iNOS expression in the dorsal horn.
Mol Pain
, 10
(1)
39 - ?.
10.1186/1744-8069-10-39.
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2012
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Obara, I;
Géranton, SM;
Hunt, SP;
(2012)
Axonal protein synthesis: a potential target for pain relief?
Current Opinion in Pharmacology
, 12
(1)
42 - 48.
10.1016/j.coph.2011.10.005.
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2009
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Vega-Avelaira, D;
Geranton, SM;
Fitzgerald, M;
(2009)
Differential regulation of immune responses and macrophage/neuron interactions in the dorsal root ganglion in young and adult rats following nerve injury.
Molecular Pain
, 5
, Article 70. 10.1186/1744-8069-5-70.
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2008
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Geranton, SM;
Fratto, V;
Tochiki, KK;
Hunt, SP;
(2008)
Descending serotonergic controls regulate inflammation-induced induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn.
Molecular Pain
, 4
, Article 35. 10.1186/1744-8069-4-35.
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Jimenez-Diaz, L;
Geranton, SM;
Passmore, GM;
Leith, JL;
Fisher, AS;
Berliocchi, L;
Sivasubramaniam, AK;
... Hunt, SP; + view all
(2008)
Local Translation in Primary Afferent Fibers Regulates Nociception.
PLOS ONE
, 3
(4)
, Article e1961. 10.1371/journal.pone.0001961.
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2007
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Geranton, SM;
Morenilla-Palao, C;
Hunt, SP;
(2007)
A role for transcriptional repressor methyl-CpG-binding protein 2 and plasticity-related gene serum- and glucocorticoid-inducible kinase 1 in the induction of inflammatory pain states.
J NEUROSCI
, 27
(23)
6163 - 6173.
10.1523/JNEUROSCI.1306-07.2007.
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