Browse by UCL people
Group by: Type | Date
Number of items: 21.
2025
Arroyo-Berdugo, Yoana;
Di Mambro, Antonella;
Behrends, Volker;
Sahai, Michelle A;
Cozzuto, Luca;
Zollo, Immacolata;
Ponomarenko, Julia;
... Esposito, Maria Teresa; + view all
(2025)
Exploiting PP2A dependent and independent effects of forskolin for therapeutic targeting of KMT2A (MLL)-rearranged acute leukaemia.
British Journal of Pharmacology
, 182
(24)
pp. 6043-6062.
10.1111/bph.70158.
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Lim, Bram SJ;
Whitfield, Holly J;
Trinh, Mi K;
Bloye, Gianna;
Thomas, Rebecca;
Anderson, Nathaniel D;
Wenger, Anna;
... O'connor, David; + view all
(2025)
A non-canonical lymphoblast in refractory childhood T-cell leukaemia.
Nature Communications
, 16
(1)
, Article 9397. 10.1038/s41467-025-65049-8.
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2024
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Cantilena, Sandra;
Alameri, Mohamed;
Che, Noelia;
Williams, Owen;
de Boer, Jasper;
(2024)
Synergistic Strategies for KMT2A-Rearranged Leukemias: Beyond Menin Inhibitor.
Cancers
, 16
(23)
, Article 4017. 10.3390/cancers16234017.
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Che, Noelia;
Cantilena, Sandra;
Looi-Somoye, Remi;
Sundar, Danesh;
Fung, Kent;
de Boer, Jasper;
Williams, Owen;
(2024)
Enhanced depletion of MLL-fusion proteins in acute leukemia: potential for improved therapeutic outcomes.
Experimental Hematology & Oncology
, 13
(1)
, Article 84. 10.1186/s40164-024-00556-w.
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Karsa, Mawar;
Xiao, Lin;
Ronca, Emma;
Bongers, Angelika;
Spurling, Dayna;
Karsa, Ayu;
Cantilena, Sandra;
... Somers, Klaartje; + view all
(2024)
FDA-approved disulfiram as a novel treatment for aggressive leukemia.
Journal of Molecular Medicine
10.1007/s00109-023-02414-4.
(In press).
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2023
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Bueno, Clara;
Torres-Ruíz, Raul;
Velasco-Hernandez, Talia;
Molina, Oscar;
Petazzi, Paolo;
Martinez-Moreno, Alba;
Rodríguez-Cortez, Virginia Carolina;
... Menendez, Pablo; + view all
(2023)
A human genome editing-based MLL::AF4 B-cell ALL model recapitulates key cellular and molecular leukemogenic features.
Blood
10.1182/blood.2023020858.
(In press).
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Di Mambro, Antonella;
Arroyo-Berdugo, Yoana;
Fioretti, Tiziana;
Randles, Michael;
Cozzuto, Luca;
Rajeeve, Vinothini;
Cevenini, Armando;
... Esposito, Maria Teresa; + view all
(2023)
SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML.
Oncogene
10.1038/s41388-023-02840-1.
(In press).
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Gasparoli, Luca;
Virely, Clemence;
Tsakaneli, Alexia;
Che, Noelia;
Edwards, Darren;
Bartram, Jack;
Hubank, Michael;
... Williams, Owen; + view all
(2023)
Susceptibility of pediatric acute lymphoblastic leukemia to STAT3 inhibition depends on p53 induction.
Haematologica
10.3324/haematol.2023.283613.
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2022
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Cantilena, Sandra;
Gasparoli, Luca;
Pal, Deepali;
Heidenreich, Olaf;
Klusmann, Jan-Henning;
Martens, Joost HA;
Faille, Alexandre;
... de Boer, Jasper; + view all
(2022)
Direct targeted therapy for MLL-fusion-driven high-risk acute leukaemias.
Clinical and Translational Medicine
, 12
(6)
, Article e933. 10.1002/ctm2.933.
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Clesham, Katherine;
Walf-Vorderwülbecke, Vanessa;
Gasparoli, Luca;
Virely, Clemence;
Cantilena, Sandra;
Tsakaneli, Alexia;
Inglott, Sarah;
... Williams, Owen; + view all
(2022)
Identification of a c-MYB-directed therapeutic for acute myeloid leukemia.
Leukemia
10.1038/s41375-022-01554-9.
(In press).
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Khabirova, E;
Jardine, L;
Coorens, THH;
Webb, S;
Treger, TD;
Engelbert, J;
Porter, T;
... Behjati, S; + view all
(2022)
Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia.
Nature Medicine
10.1038/s41591-022-01720-7.
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Maciocia, Paul Michael;
Wawrzyniecka, Patrycja A;
Maciocia, Nicola C;
Burley, Amy;
Karpanasamy, Thaneswari;
Devereaux, Sam;
Hoekx, Malika;
... Mansour, Marc R; + view all
(2022)
Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia.
Blood
, 140
(1)
pp. 25-37.
10.1182/blood.2021013648.
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2021
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Tsakaneli, A;
Williams, O;
(2021)
Drug Repurposing for Targeting Acute Leukemia With KMT2A (MLL)-Gene Rearrangements.
Frontiers in Pharmacology
, 12
, Article 741413. 10.3389/fphar.2021.741413.
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2020
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Park, E;
Chen, J;
Moore, A;
Mangolini, M;
Santoro, A;
Boyd, JR;
Schjerven, H;
... Ringshausen, I; + view all
(2020)
Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance.
Science Translational Medicine
, 12
(526)
, Article eaax9340. 10.1126/scitranslmed.aax9340.
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Virely, C;
Gasparoli, L;
Mangolini, M;
Clesham, K;
Inglott, S;
Edwards, D;
Adams, S;
... Williams, O; + view all
(2020)
ARHGEF4 Regulates an Essential Oncogenic Program in t(12;21)-Associated Acute Lymphoblastic Leukemia.
HemaSphere
, 4
(5)
, Article e467. 10.1097/HS9.0000000000000467.
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2019
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Armenteros-Monterroso, E;
Zhao, L;
Gasparoli, L;
Brooks, T;
Pearce, K;
Mansour, MR;
Martens, JHA;
... Williams, O; + view all
(2019)
The AAA+ATPase RUVBL2 is essential for the oncogenic function of c-MYB in acute myeloid leukemia.
Leukemia
, 33
pp. 2817-2829.
10.1038/s41375-019-0495-8.
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2018
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Cantilena, Sandra;
(2018)
Drug induced degradation of driver proteins: A novel approach to target MLL-fusions.
Doctoral thesis (Ph.D), UCL (University College London).
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Tijchon, E;
van Emst, L;
Yuniati, L;
van Ingen Schenau, D;
Gerritsen, M;
van der Meer, LT;
Williams, O;
... van Leeuwen, FN; + view all
(2018)
Tumor suppressor BTG1 limits activation of BCL6 expression downstream of ETV6-RUNX1.
Experimental Hematology
, 60
57-62.e3.
10.1016/j.exphem.2018.01.006.
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Walf-Vorderwülbecke, V;
Pearce, K;
Brooks, T;
Hubank, M;
Van den Heuvel-Eibrink, MM;
Zwaan, CM;
Adams, S;
... Williams, O; + view all
(2018)
Targeting acute myeloid leukemia by drug-induced c-MYB degradation.
Leukemia
, 32
pp. 882-889.
10.1038/leu.2017.317.
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2016
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Stasevich, I;
(2016)
Characterisation of genetically unclassified subtypes of childhood B-Cell Precursor Acute Lymphoblastic leukaemia.
Doctoral thesis , UCL (University College London).
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2014
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Zhao, L;
(2014)
Identify critical signalling pathways in MLL-rearranged acute myeloid leukaemia.
Doctoral thesis , UCL (University College London).
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