Browse by UCL people
Group by: Type | Date
Number of items: 24.
Article
Bats, C;
Farrant, M;
Cull-Candy, SG;
(2013)
A role of TARPs in the expression and plasticity of calcium-permeable AMPARs: evidence from cerebellar neurons and glia.
Neuropharmacology
, 74
(Novemb)
76 - 85.
10.1016/j.neuropharm.2013.03.037.
|
    |
|
Cais, O;
Herguedas, B;
Krol, K;
Cull-Candy, SG;
Farrant, M;
Greger, IH;
(2014)
Mapping the Interaction Sites between AMPA Receptors and TARPs Reveals a Role for the Receptor N-Terminal Domain in Channel Gating.
Cell Reports
, 9
(2)
pp. 728-740.
10.1016/j.celrep.2014.09.029.
|
 |
|
Coombs, Ian;
Sexton, Craig A;
Cull-Candy, Stuart G;
Farrant, Mark;
(2022)
Influence of the TARP γ8-selective negative allosteric modulator JNJ-55511118 on AMPA receptor gating and channel conductance.
Molecular Pharmacology
10.1124/molpharm.121.000473.
(In press).
|
|
Coombs, Ian D;
Bats, Cécile;
Sexton, Craig A;
Studniarczyk, Dorota;
Cull-Candy, Stuart G;
Farrant, Mark;
(2023)
Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM.
eLife
, 12
, Article e66765. 10.7554/eLife.66765.
|
|
|
Coombs, Ian D;
Farrant, Mark;
(2023)
An unexpected role for a glutamate receptor.
Science
, 382
(6677)
pp. 1363-1364.
10.1126/science.adm6771.
|
|
Coombs, Ian D;
Ziobro, Julie;
Krotov, Volodymyr;
Surtees, Taryn-Leigh;
Cull-Candy, Stuart G;
Farrant, Mark;
(2022)
A gain-of-function GRIA2 variant associated with neurodevelopmental delay and seizures: functional characterization and targeted treatment.
Epilepsia
, 63
(12)
e156-e163.
10.1111/epi.17419.
|
|
Coombs, ID;
MacLean, DM;
Jayaraman, V;
Farrant, M;
Cull-Candy, SG;
(2017)
Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation.
Cell reports
, 20
(5)
pp. 1123-1135.
10.1016/j.celrep.2017.07.014.
|
|
|
Coombs, ID;
Soto, D;
McGee, TP;
Gold, MG;
Farrant, M;
Cull-Candy, SG;
(2019)
Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nature Communications
, 10
(1)
, Article 4312. 10.1038/s41467-019-12280-9.
|
|
|
Cull-Candy, SG;
Farrant, M;
(2021)
Ca2+ -permeable AMPA receptors and their auxiliary subunits in synaptic plasticity and disease.
The Journal of Physiology
10.1113/JP279029.
(In press).
|
|
|
Davenport, EC;
Pendolino, V;
Kontou, G;
McGee, TP;
Sheehan, DF;
López-Doménech, G;
Farrant, M;
(2017)
An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors.
Cell Reports
, 21
(1)
pp. 70-83.
10.1016/j.celrep.2017.09.025.
|
|
Lalanne, T;
Oyrer, J;
Mancino, A;
Gregor, E;
Chung, A;
Huynh, L;
Burwell, S;
... Sjoestroem, PJ; + view all
(2016)
Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5.
JOURNAL OF PHYSIOLOGY-LONDON
, 594
(4)
pp. 837-861.
10.1113/JP271394.
|
|
|
Lalanne, T;
Oyrer, J;
Farrant, M;
Sjöström, PJ;
(2018)
Synapse Type-Dependent Expression of Calcium-Permeable AMPA Receptors.
Frontiers in Synaptic Neuroscience
, 10
, Article 34. 10.3389/fnsyn.2018.00034.
|
|
|
Magno, L;
Asgarian, Z;
Pendolino, V;
Velona, T;
Mackintosh, A;
Lee, F;
Stryjewska, A;
... Kessaris, N; + view all
(2021)
Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior.
Cell Reports
, 35
(11)
, Article 109249. 10.1016/j.celrep.2021.109249.
|
|
|
McGee, Thomas;
Bats, Cecile;
Farrant, Mark;
Cull-Candy, Stuart;
(2025)
Intracellular spermine is a key player in GSG1L’s regulation of calcium permeable AMPAR channel conductance and recovery from desensitization.
Journal of Neuroscience
, Article e1930242025. 10.1523/JNEUROSCI.1930-24.2025.
|
|
McGee, TP;
Bats, C;
Farrant, M;
Cull-Candy, SG;
(2015)
Auxiliary Subunit GSG1L Acts to Suppress Calcium-Permeable AMPA Receptor Function.
Journal of Neuroscience
, 35
(49)
pp. 16171-16179.
10.1523/JNEUROSCI.2152-15.2015.
|
|
Rigby, M;
Cull-Candy, SG;
Farrant, M;
(2015)
Transmembrane AMPAR regulatory protein γ-2 is required for the modulation of GABA release by presynaptic AMPARs.
Journal of Neuroscience
, 35
(10)
4203 - 4214.
10.1523/JNEUROSCI.4075-14.2015.
|
|
Soto, D;
Coombs, ID;
Gratacòs-Batlle, E;
Farrant, M;
Cull-Candy, SG;
(2014)
Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors.
The Journal of Neuroscience
, 34
(35)
pp. 11673-11683.
10.1523/JNEUROSCI.0383-14.2014.
|
|
Studniarczyk, D;
Coombs, I;
Cull-Candy, SG;
Farrant, M;
(2013)
TARP γ-7 selectively enhances synaptic expression of calcium-permeable AMPARs.
Nature Neuroscience
, 16
(9)
pp. 1266-1274.
10.1038/nn.3473.
|
|
Studniarczyk, D;
Needham, E;
Mitchison, H;
Farrant, M;
Cull-Candy, S;
(2018)
Altered Cerebellar Short-Term Plasticity but No Change in Postsynaptic AMPA-Type Glutamate Receptors in a Mouse Model of Juvenile Batten Disease.
eNeuro
, 5
(2)
, Article e0387. 10.1523/ENEURO.0387-17.2018.
|
|
Sullivan, SJ;
Farrant, M;
Cull-Candy, SG;
(2017)
TARP γ-2 is required for inflammation-associated AMPA receptor plasticity within lamina II of the spinal cord dorsal horn.
Journal of Neuroscience
, 37
(25)
pp. 6007-6020.
10.1523/JNEUROSCI.0772-16.2017.
|
|
Zonouzi, M;
Scafidi, J;
Li, P;
McEllin, B;
Edwards, J;
Dupree, JL;
Harvey, L;
... Gallo, V; + view all
(2015)
GABAergic regulation of cerebellar NG2 cell development is altered in perinatal white matter injury.
Nat Neurosci
, 18
(5)
pp. 674-682.
10.1038/nn.3990.
|
Working / discussion paper
|
Coombs, I;
Soto, D;
McGee, T;
Gold, M;
Farrant, M;
Cull-Candy, S;
(2019)
Homomeric Q/R edited AMPA receptors conduct when desensitized.
BioRxiv: Cold Spring Harbor, NY, USA.
|
Poster
|
Cabet, Sara;
Maheshwari, Atul;
Noebels, Jeffrey;
Goldman, Alica;
Farrant, Mark;
Cull-Candy, Stuart;
Coombs, Ian;
... Lesca, Gaetan; + view all
(2023)
Role of CACNG2 variants in human pathology.
Presented at: 56th Annual Conference of the European Society of Human Genetics (ESHG), Glasgow, UK.
|
Thesis
|
Farrant, M;
(1987)
Inhibitory neurotransmission and amino acid release in the substantia nigra of the rat. Ph.D., University of London.
Doctoral thesis , UNSPECIFIED.
|
