Browse by UCL people
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Number of items: 39.
Article
Afik, S;
Yates, KB;
Bi, K;
Darko, S;
Godec, J;
Gerdemann, U;
Swadling, L;
... Yosef, N; + view all
(2017)
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state.
Nucleic Acids Research
, 45
(16)
, Article e148. 10.1093/nar/gkx615.
|
Alsaleh, G;
Panse, I;
Swadling, L;
Zhang, H;
Richter, FC;
Meyer, A;
Lord, J;
... Simon, AK; + view all
(2020)
Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses.
eLife
, 9
, Article e57950. 10.7554/eLife.57950.
|
Altmann, Daniel M;
Reynolds, Catherine J;
Joy, George;
Otter, Ashley D;
Gibbons, Joseph M;
Pade, Corinna;
Swadling, Leo;
... Boyton, Rosemary J; + view all
(2023)
Persistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity.
Nature Communications
, 14
(1)
, Article 5139. 10.1038/s41467-023-40460-1.
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Balloux, François;
Tan, Cedric;
Swadling, Leo;
Richard, Damien;
Jenner, Charlotte;
Maini, Mala;
van Dorp, Lucy;
(2022)
The past, current and future epidemiological dynamic of SARS-CoV-2.
Oxford Open Immunology
, 3
(1)
, Article iqac003. 10.1093/oxfimm/iqac003.
|
Burton, AR;
Pallett, LJ;
McCoy, LE;
Suveizdyte, K;
Amin, OE;
Swadling, L;
Alberts, E;
... Maini, MK; + view all
(2018)
Circulating and intrahepatic antiviral B cells are defective in hepatitis B.
Journal of Clinical Investigation
, 2018
pp. 1-16.
10.1172/JCI121960.
|
Cankat, S;
Demael, MU;
Swadling, L;
(2023)
In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms.
Cellular & Molecular Immunology
10.1038/s41423-023-01116-8.
(In press).
|
Cannizzo, ES;
Cerrone, M;
Merlini, E;
van Wilgenburg, B;
Swadling, L;
Ancona, G;
De Bona, A;
... Marchetti, G; + view all
(2019)
Successful direct-acting antiviral therapy in HIV/HCV co-infected patients fails to restore circulating mucosal-associated invariant T cells.
[Letter].
European Journal Of Immunology
, 49
(7)
pp. 1127-1129.
10.1002/eji.201948152.
|
Capone, S;
Brown, A;
Hartnell, F;
Del Sorbo, MD;
Traboni, C;
Vassilev, V;
Colloca, S;
... Swadling, L; + view all
(2020)
Optimising T cell (re)boosting strategies for adenoviral and modified vaccinia Ankara vaccine regimens in humans.
npj Vaccines
, 5
, Article 94. 10.1038/s41541-020-00240-0.
|
Chandran, Aneesh;
Rosenheim, Joshua;
Nageswaran, Gayathri;
Swadling, Leo;
Pollara, Gabriele;
Gupta, Rishi K;
Burton, Alice R;
... Noursadeghi, Mahdad; + view all
(2022)
Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections.
Cell Reports Medicine
, Article 100557. 10.1016/j.xcrm.2022.100557.
(In press).
|
Diniz, Mariana O;
Mitsi, Elena;
Swadling, Leo;
Rylance, Jamie;
Johnson, Marina;
Goldblatt, David;
Ferreira, Daniela;
(2022)
Airway-resident T cells from unexposed individuals cross-recognize SARS-CoV-2.
Nature Immunology
10.1038/s41590-022-01292-1.
(In press).
|
Diniz, MO;
Maini, MK;
Swadling, L;
(2023)
T cell control of SARS-CoV-2: When, which, and where?
Seminars in Immunology
, 70
, Article 101828. 10.1016/j.smim.2023.101828.
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Donnison, T;
Von Delft, A;
Brown, A;
Swadling, L;
Hutchings, C;
Hanke, T;
Chinnakannan, S;
(2020)
Viral vectored hepatitis C virus vaccines generate pan-genotypic T cell responses to conserved subdominant epitopes.
Vaccine
, 38
(32)
pp. 5036-5048.
10.1016/j.vaccine.2020.05.042.
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Easom, NJW;
Stegmann, KA;
Swadling, L;
Pallett, LJ;
Burton, AR;
Odera, D;
Schmidt, N;
... Maini, MK; + view all
(2018)
IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.
Frontiers in Immunology
, 9
, Article 1009. 10.3389/fimmu.2018.01009.
|
Esposito, I;
Cicconi, P;
D'Alise, AM;
Brown, A;
Esposito, M;
Swadling, L;
Holst, PJ;
... PEACHI Consortium; + view all
(2020)
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans.
Science Translational Medicine
, 12
(548)
, Article eaaz7715. 10.1126/scitranslmed.aaz7715.
|
Gordon, CL;
Lee, LN;
Swadling, L;
Hutchings, C;
Zinser, M;
Highton, AJ;
Capone, S;
... Klenerman, P; + view all
(2018)
Induction and Maintenance of CX3CR1-Intermediate Peripheral Memory CD8(+) T Cells by Persistent Viruses and Vaccines.
Cell Reports
, 23
(3)
pp. 768-782.
10.1016/j.celrep.2018.03.074.
|
Hartnell, F;
Esposito, I;
Swadling, L;
Brown, A;
Phetsouphanh, C;
de Lara, C;
Gentile, C;
... Klenerman, P; + view all
(2020)
Characterizing Hepatitis C Virus–Specific CD4+ T Cells Following Viral‐Vectored Vaccination, Directly Acting Antivirals, and Spontaneous Viral Cure.
Hepatology
, 72
(5)
pp. 1541-1555.
10.1002/hep.31160.
|
Hartnell, F;
Brown, A;
Capone, S;
Kopycinski, J;
Bliss, C;
Makvandi-Nejad, S;
Swadling, L;
... Dorrell, L; + view all
(2019)
A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection.
Frontiers In Immunology
, 9
, Article 3175. 10.3389/fimmu.2018.03175.
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Lindeboom, Rik GH;
Worlock, Kaylee B;
Dratva, Lisa M;
Yoshida, Masahiro;
Scobie, David;
Wagstaffe, Helen R;
Richardson, Laura;
... Teichmann, Sarah A; + view all
(2024)
Author Correction: Human SARS-CoV-2 challenge uncovers local and systemic response dynamics.
Nature
, 632
, Article E3. 10.1038/s41586-024-07838-7.
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Lindeboom, Rik GH;
Worlock, Kaylee B;
Dratva, Lisa M;
Yoshida, Masahiro;
Scobie, David;
Wagstaffe, Helen R;
Richardson, Laura;
... Teichmann, Sarah A; + view all
(2024)
Human SARS-CoV-2 challenge uncovers local and systemic response dynamics.
Nature
, 631
pp. 189-198.
10.1038/s41586-024-07575-x.
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Mazouz, S;
Salinas, E;
Bédard, N;
Filali, A;
Khedr, O;
Swadling, L;
Abdel-Hakeem, MS;
... Shoukry, NH; + view all
(2022)
Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects.
PLoS Pathogens
, 18
(11)
, Article e1010968. 10.1371/journal.ppat.1010968.
|
Merlini, E;
Cerrone, M;
van Wilgenburg, B;
Swadling, L;
Stefania Cannizzo, E;
Monforte, AD;
Klenerman, P;
(2019)
Association between impaired vα7.2+cd161++cd8+ (MAIT) and vα7.2+cd161-cd8+ t-cell populations and gut dysbiosis in chronically HIV-and/or HCV-infected patients.
Frontiers in Microbiology
, 10
, Article 1972. 10.3389/fmicb.2019.01972.
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Pallett, Laura J;
Swadling, Leo;
Diniz, Mariana;
Maini, Alexander A;
Schwabenland, Marius;
Gasull, Adrià Dalmau;
Davies, Jessica;
... Maini, Mala K; + view all
(2023)
Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.
Nature
, 614
pp. 334-342.
10.1038/s41586-022-05645-6.
|
Pallett, LJ;
Burton, AR;
Amin, OE;
Rodriguez-Tajes, S;
Patel, AA;
Zakeri, N;
Jeffery-Smith, A;
... Maini, MK; + view all
(2020)
Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes.
Journal of Experimental Medicine
, 217
(9)
, Article e20200050. 10.1084/jem.20200050.
|
Pallett, LJ;
Davies, J;
Colbeck, EJ;
Robertson, F;
Hansi, N;
Easom, NJW;
Burton, AR;
... Maini, MK; + view all
(2017)
IL-2(high) tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.
Journal of Experimental Medicine
, 214
(6)
pp. 1567-1580.
10.1084/jem.20162115.
|
Reynolds, CJ;
Pade, C;
Gibbons, JM;
Butler, DK;
Otter, AD;
Menacho, K;
Fontana, M;
... Boyton, R; + view all
(2021)
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.
Science
, Article eabh1282. 10.1126/science.abh1282.
(In press).
|
Reynolds, CJ;
Swadling, L;
Gibbons, JM;
Pade, C;
Jensen, MP;
Diniz, MO;
Schmidt, NM;
... Boyton, RJ; + view all
(2020)
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection.
Science Advances
, 5
(54)
, Article eabf3698. 10.1126/sciimmunol.abf3698.
|
Sartorius, K;
Swadling, L;
An, P;
Makarova, J;
Winkler, C;
Chuturgoon, A;
Kramvis, A;
(2020)
The Multiple Roles of Hepatitis B Virus X Protein (HBx) Dysregulated MicroRNA in Hepatitis B Virus-Associated Hepatocellular Carcinoma (HBV-HCC) and Immune Pathways.
Viruses
, 12
(7)
, Article 746. 10.3390/v12070746.
|
Schmidt, NM;
Wing, PAC;
Diniz, MO;
Pallett, LJ;
Swadling, L;
Harris, JM;
Burton, AR;
... Maini, MK; + view all
(2021)
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Nature Communications
, 12
, Article 2814. 10.1038/s41467-021-22967-7.
|
Stamataki, Z;
Swadling, L;
(2020)
The Liver as an Immunological Barrier Redefined by Single Cell Analysis.
Immunology
, 160
(2)
pp. 157-170.
10.1111/imm.13193.
|
Stelma, F;
van der Ree, MH;
Sinnige, MJ;
Brown, A;
Swadling, L;
de Vree, JML;
Willemse, SB;
... Reesink, HW; + view all
(2017)
Immune Phenotype and Function of Natural Killer and T Cells in Chronic Hepatitis C Patients Who Received a Single Dose of Anti-MicroRNA-122, RG-101.
Hepatology
, 66
(1)
pp. 57-68.
10.1002/hep.29148.
|
Swadling, L;
Diniz, MO;
Schmidt, NM;
Amin, OE;
Chandran, A;
Shaw, E;
Pade, C;
... Maini, MK; + view all
(2022)
Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2.
Nature
, 601
pp. 110-117.
10.1038/s41586-021-04186-8.
|
Swadling, L;
Maini, MK;
(2020)
T cells in COVID-19 — united in diversity.
Nature Immunology
, 21
pp. 1307-1308.
10.1038/s41590-020-0798-y.
|
Swadling, Leo;
Maini, Mala K;
(2023)
Can T Cells Abort SARS-CoV-2 and Other Viral Infections?
International Journal of Molecular Sciences
, 24
(5)
, Article 4371. 10.3390/ijms24054371.
|
Swadling, L;
Halliday, J;
Kelly, C;
Brown, A;
Capone, S;
Ansari, MA;
Bonsall, D;
... Barnes, E; + view all
(2016)
Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection.
Vaccines
, 4
(3)
, Article 27. 10.3390/vaccines4030027.
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Swadling, L;
Pallett, LJ;
Diniz, MO;
Baker, JM;
Amin, OE;
Stegmann, KA;
Burton, AR;
... Maini, MK; + view all
(2020)
Human Liver Memory CD8+ T Cells Use Autophagy for Tissue Residence.
Cell Reports
, 30
(3)
687-698.e6.
10.1016/j.celrep.2019.12.050.
|
Swadling, L;
Pallett, LJ;
Maini, MK;
(2020)
Liver-resident CD8+ T cells: learning lessons from the local experts.
Journal of Hepatology
, 72
(6)
pp. 1049-1051.
10.1016/j.jhep.2020.02.001.
|
van der Ree, MH;
Stelma, F;
Willemse, SB;
Brown, A;
Swadling, L;
van der Valk, M;
Sinnige, MJ;
... Reesink, HW; + view all
(2017)
Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing.
Antiviral Research
, 146
pp. 139-145.
10.1016/j.antiviral.2017.08.016.
|
Wagstaffe, Helen R;
Thwaites, Ryan S;
Sidhu, Jasmin K;
Lindeboom, Rik GH;
Kretschmer, Lorenz;
Worlock, Kaylee B;
Dratva, Lisa M;
... Chiu, Christopher; + view all
(2025)
Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infection.
Nature Communications
10.1038/s41467-025-67017-8.
(In press).
|
Zakeri, N;
Hall, A;
Swadling, L;
Pallett, LJ;
Schmidt, NM;
Diniz, MO;
Kucykowicz, S;
... Maini, MK; + view all
(2022)
Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma.
Nature Communications
, 13
, Article 1372. 10.1038/s41467-022-29012-1.
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