Browse by UCL people
Group by: Type | Date
Number of items: 21.
2025
Habib, Abdella M;
Li, Shengnan;
Zhang, Chenjing;
Ji, Meijun;
Osorio, Nancy;
Penalba, Virginie;
Torres, Jesus M;
... Coste, Bertrand; + view all
(2025)
MDFIC2 is a PIEZO channel modulator that can alleviate mechanical allodynia associated with neuropathic pain.
Proceedings of the National Academy of Sciences
, 122
(45)
, Article e2512426122. 10.1073/pnas.2512426122.
|
|
Wood, John N;
Yan, Nieng;
Huang, Jian;
Zhao, Jing;
Akopian, Armen;
Cox, James J;
Woods, C Geoffrey;
(2025)
Sensory neuron sodium channels as pain targets; from cocaine to Journavx (VX-548, suzetrigine).
The Journal of General Physiology
, 157
(4)
, Article e202513778. 10.1085/jgp.202513778.
|
 |
2024
|
Bangash, M Ali;
Cubuk, Cankut;
Iseppon, Federico;
Haroun, Rayan;
Garcia, Chloe;
Luiz, Ana P;
Arcangeletti, Manuel;
... Zhao, Jing; + view all
(2024)
Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes.
Cell Reports
, 43
(8)
, Article 114614. 10.1016/j.celrep.2024.114614.
|
|
|
Gao, Li;
Zhang, Ai-ping;
Fu, Lei;
Li, Qian-wen;
Qin, Xue-mei;
Zhao, Jing;
(2024)
Huangqin decoction attenuates spared nerve injury (SNI)-induced neuropathic pain by modulating microglial M1/M2 polarization partially mediated by intestinal nicotinamide metabolism.
Phytomedicine
, 129
, Article 155594. 10.1016/j.phymed.2024.155594.
|
|
Iseppon, Federico;
Kanellopoulos, Alexandros H;
Tian, Naxi;
Caan, Gozde;
Chiozzi, Riccardo;
Thalassinos, Konstantinos;
Cubuk, Cankut;
... Wood, John N; + view all
(2024)
Sodium channels Nav1.7, Nav1.8 and pain; two distinct mechanisms for Nav1.7 null analgesia.
Neurobiology of Pain
, 16
, Article 100168. 10.1016/j.ynpai.2024.100168.
|
2023
|
Gao, Li;
Zhao, Jin-Xia;
Qin, Xue-Mei;
Zhao, Jing;
(2023)
The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptor.
Journal of Ethnopharmacology
, 317
, Article 116762. 10.1016/j.jep.2023.116762.
|
|
Haroun, Rayan;
Gossage, Samuel J;
Luiz, Ana Paula;
Arcangeletti, Manuel;
Sikandar, Shafaq;
Zhao, Jing;
Cox, James J;
(2023)
Chemogenetic silencing of NaV1.8 positive sensory neurons reverses chronic neuropathic and bone cancer pain in FLEx PSAM4-GlyR mice.
eNeuro
, 10
(9)
, Article ENEURO.0151-23.2023. 10.1523/ENEURO.0151-23.2023.
|
|
Jami, Sina;
Deuis, Jennifer R;
Klasfauseweh, Tabea;
Cheng, Xiaoyang;
Kurdyukov, Sergey;
Chung, Felicity;
Okorokov, Andrei L;
... Vetter, Irina; + view all
(2023)
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.
Nature Communications
, 14
, Article 2442. 10.1038/s41467-023-37963-2.
|
|
|
Wang, Jing;
Ru, Qiao-Min;
Yu, Xiao-Hui;
Wang, Changlong;
Li, Kai;
Han, Chao-Zhen-Yi;
Li, Na;
... Wang, Yuan; + view all
(2023)
Direct inhibition of microglial activation by a μ receptor selective agonist alleviates inflammatory-induced pain hypersensitivity.
European Journal of Pharmacology
, 961
, Article 176182. 10.1016/j.ejphar.2023.176182.
|
2022
|
Schmidt, Manuela;
Sondermann, Julia Regina;
Gomez-Varela, David;
Çubuk, Cankut;
Millet, Queensta;
Lewis, Myles J;
Wood, John N;
(2022)
Transcriptomic and proteomic profiling of NaV1.8-expressing mouse nociceptors.
Frontiers in Molecular Neuroscience
, 15
, Article 1002842. 10.3389/fnmol.2022.1002842.
|
2021
|
MacDonald, DI;
Sikandar, S;
Weiss, J;
Pyrski, M;
Luiz, AP;
Millet, Q;
Emery, EC;
... Wood, JN; + view all
(2021)
A central mechanism of analgesia in mice and humans lacking the sodium channel NaV1.7.
Neuron
10.1016/j.neuron.2021.03.012.
(In press).
|
|
|
Santana-Varela, S;
Bogdanov, YD;
Gossage, SJ;
Okorokov, AL;
Li, S;
de Clauser, L;
Alves-Simoes, M;
... Cox, JJ; + view all
(2021)
Tools for analysis and conditional deletion of subsets of sensory neurons [version 1; peer review: 4 approved].
Wellcome Open Research
, 6
, Article 250. 10.12688/wellcomeopenres.17090.1.
|
2020
|
Alles, SRA;
Nascimento, F;
Luján, R;
Luiz, AP;
Millet, Q;
Bangash, MA;
Santana-Varela, S;
... Wood, JN; + view all
(2020)
Sensory neuron–derived NaV1.7 contributes to dorsal horn neuron excitability.
Science Advances
, 6
(8)
, Article eaax4568. 10.1126/sciadv.aax4568.
|
|
2018
|
Bangash, MA;
Alles, SRA;
Santana-Varela, S;
Millet, Q;
Sikandar, S;
de Clauser, L;
Ter Heegde, F;
... Wood, JN; + view all
(2018)
Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions.
Wellcome Open Research
, 3
, Article 78. 10.12688/wellcomeopenres.14641.1.
|
|
|
Habib, AM;
Matsuyama, A;
Okorokov, AL;
Santana, S;
Bras, JT;
Aloisi, AM;
Emery, EC;
... Cox, JJ; + view all
(2018)
A novel human pain insensitivity disorder caused by a point mutation in ZFHX2.
Brain
, 141
(2)
pp. 365-376.
10.1093/brain/awx326.
|
|
|
Kanellopoulos, AH;
Koenig, J;
Huang, H;
Pyrski, M;
Millet, Q;
Lolignier, S;
Morohashi, T;
... Zhao, J; + view all
(2018)
Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene targeted mice.
The EMBO Journal
, 37
(3)
pp. 427-445.
10.15252/embj.201796692.
|
|
|
Sexton, JE;
Cox, JJ;
Zhao, J;
Wood, JN;
(2018)
The Genetics of Pain: Implications for Therapeutics.
Annual Review of Pharmacology and Toxicology
, 58
pp. 123-142.
10.1146/annurev-pharmtox-010617-052554.
|
|
Sikandar, S;
Minett, MS;
Millet, Q;
Santana, S;
Lau, J;
Wood, JN;
Zhao, J;
(2018)
Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain.
Brain
, 141
(4)
pp. 1028-1039.
10.1093/brain/awy009.
|
2016
|
Neumann, E;
Brandenburger, T;
Santana-Varela, S;
Deenen, R;
Köhrer, K;
Bauer, I;
Hermanns, H;
... Werdehausen, R; + view all
(2016)
MicroRNA-1-associated effects of neuron-specific brain-derived neurotrophic factor gene deletion in dorsal root ganglia.
Molecular and Cellular Neuroscience
, 75
pp. 36-43.
10.1016/j.mcn.2016.06.003.
|
2015
|
Minett, MS;
Pereira, V;
Sikandar, S;
Matsuyama, A;
Lolignier, S;
Kanellopoulos, AH;
Mancini, F;
... Wood, JN; + view all
(2015)
Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7.
Nature Communications
, 6
, Article 8967. 10.1038/ncomms9967.
|
|
2005
|
Moore, R.M.;
Pinel, T.;
Zhao, J.H.;
March, R.;
Jawaid, A.;
(2005)
Selecting cases from nuclear families for case-control association analysis.
BMC Genetics
, 6
(S1)
S105.
10.1186/1471-2156-6-S1-S105.
|
 |
