Browse by UCL people
Group by: Type | Date
Number of items: 13.
Article
Ahmed, Nada M;
Eddama, Mohammad MR;
Beatson, Kevin;
Gurung, Rijan;
Patel, Jigisha;
Iskandar, Georges;
Abdel-Salam, Alaa;
... Clapp, Lucie; + view all
(2024)
Circulating large extracellular vesicles as diagnostic biomarkers of indeterminate thyroid nodules: multi-platform omics analysis.
BJS OPEN
, 9
(1)
, Article zrae139. 10.1093/bjsopen/zrae139.
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Ahmed, Nada Mabrouk;
Beatson, Kevin;
Patel, Jigisha;
Eddama, Mohammad Mahmoud Rajab;
Clapp, Lucie H;
Abdel-Aziz, Tarek;
(2025)
The diagnostic and prognostic potential of extracellular vesicles as biomarkers for thyroid cancer: a systematic review.
Journal of Molecular Medicine
10.1007/s00109-025-02594-1.
(In press).
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Clapp, LH;
Patel, J;
(2010)
The mechanistic basis for prostacyclin action in pulmonary hypertension.
[Review].
International Journal of Respiratory Care
, 6
(1)
pp. 27-33.
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Ozen, G;
Benyahia, C;
Amgoud, Y;
Patel, J;
Abdelazeem, H;
Bouhadoun, A;
Yung, S;
... Norel, X; + view all
(2020)
Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients.
Prostaglandins & Other Lipid Mediators
, 146
, Article 106388. 10.1016/j.prostaglandins.2019.106388.
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Patel, JA;
Shen, L;
Hall, SM;
Benyahia, C;
Norel, X;
McAnulty, RJ;
Moledina, S;
... Clapp, LH; + view all
(2018)
Prostanoid EP₂ Receptors Are Up-Regulated in Human Pulmonary Arterial Hypertension: A Key Anti-Proliferative Target for Treprostinil in Smooth Muscle Cells.
International Journal of Molecular Sciences
, 19
(8)
, Article 2372. 10.3390/ijms19082372.
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Shen, L;
Patel, JA;
Norel, X;
Moledina, S;
Whittle, BJ;
von Kessler, K;
Sista, P;
(2019)
Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension.
Biochemical Pharmacology
, 166
pp. 242-256.
10.1016/j.bcp.2019.05.026.
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Proceedings paper
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Clapp, L;
Abu-Hanna, JHJ;
PATEL, JA;
(2020)
Diverse pharmacology of prostacyclin mimetics: Implications for pulmonary hypertension.
In: Nakanishi, T and Baldwin, SH and Fineman, JR and Yamagishi, H, (eds.)
Molecular mechanism of congenital heart disease and pulmonary hypertension.
(pp. pp. 31-61).
Springer Nature: Matsue, Japan.
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Conference item
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Patel, J;
Hall, S;
Clapp, LH;
(2013)
Counteracting effects of treprostinil and endothelin (ET-1) receptor antagonists (ETRAs) on endothelin-1, ETB receptor and ECE-1 levels in pulmonary smooth muscle cells (PASMCs) derived from patients with pulmonary arterial hypertension (PAH).
Presented at: Thirteenth International Conference on Endothelin (ET-13), Tokyo, Japan.
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Patel, J;
Orie, N;
Clapp, LH;
(2010)
Phosphodiesterase-type 3 inhibitor potentiates cAMP generation and antiproliferative effects of treprostinil in pulmonary arterial smooth muscle cells from patients with pulmonary hypertension.
Presented at: ERS Annual Congress 2010, Barcelona, Spain.
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Preston, IR;
Shen, L;
Patel, J;
Sood, N;
Torres, F;
Cadaret, L;
Adams, J;
(2018)
Ralinepag Reduces Pulmonary Vascular Resistance (PVR) in a Phase 2 Study Confirming Preclinical Findings on Prostacyclin (IP) Receptors in Human Tissues.
Presented at: Chest Annual Meeting 2018, San Antonio, TX, USA.
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Shen, L;
Patel, J;
Behan, D;
Adams, J;
Clapp, LH;
(2016)
APD811, a Novel and Highly Selective Non-prostanoid IP Receptor Agonist in Smooth Muscle Cells From Patients With Pulmonary Hypertension.
Presented at: American Heart Association's 2016 Scientific Sessions and Resuscitation Science Symposium, New Orleans, LA, USA.
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Shen, L;
Patel, J;
Norel, X;
Behan, D;
Adams, J;
Clapp, LH;
(2017)
APD811 (ralinepag), a novel non-prostanoid IP receptor agonist, has potent antiproliferative and vasorelaxant properties in human pulmonary artery.
Presented at: ESC Congress 2017, Barcelona, Spain.
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Thesis
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Patel, J;
(2013)
Smooth muscle cell proliferation and endothelin pathway in pulmonary arterial hypertension: Comparative effects of current and putative therapeutic agents.
Doctoral thesis (PhD), UCL (University College London).
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