Browse by UCL people
Group by: Type | Date
Number of items: 21.
Article
Apps, John R;
Gonzalez-Meljem, Jose Mario;
Guiho, Romain;
Pickles, Jessica C;
Prince, Eric;
Schwalbe, Edward;
Joshi, Nikhil;
... Martinez-Barbera, Juan Pedro; + view all
(2024)
Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression.
Acta Neuropathologica Communications
, 12
, Article 127. 10.1186/s40478-024-01838-4.
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Apps, J;
Hutchinson, C;
Shelmerdine, S;
Virasami, A;
Winter, E;
Jacques, T;
Martinez-Barbera, J-P;
... Czech, T; + view all
(2019)
Learning from cases: Analysis of two cases of craniopharyngioma from the 19th to the 21st centuries. [version 1; peer review: 2 approved].
F1000Research
, 8
, Article 1544. 10.12688/f1000research.19626.1.
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Apps, JR;
Carreno, G;
Mario Gonzalez-Meljem, J;
Haston, S;
Guiho, R;
Cooper, JE;
Manshaei, S;
... Martinez-Barbera, JP; + view all
(2018)
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Acta Neuropathologica
, 135
(5)
pp. 757-777.
10.1007/s00401-018-1830-2.
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Apps, JR;
Hutchinson, JC;
Arthurs, OJ;
Virasami, A;
Joshi, A;
Zeller-Plumhoff, B;
Moulding, D;
... Martinez-Barbera, JP; + view all
(2016)
Imaging Invasion: Micro-CT imaging of adamantinomatous craniopharyngioma highlights cell type specific spatial relationships of tissue invasion.
Acta Neuropathol Commun
, 4
(1)
, Article 57. 10.1186/s40478-016-0321-8.
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Apps, JR;
Martinez-Barbera, JP;
(2017)
Genetically engineered mouse models of craniopharyngioma: an opportunity for therapy development and understanding of tumor biology.
Brain Pathology
, 27
(3)
pp. 364-369.
10.1111/bpa.12501.
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Apps, JR;
Martinez-Barbera, JP;
(2016)
Molecular pathology of adamantinomatous craniopharyngioma: Review and opportunities for practice.
Neurosurgical Focus
, 41
(6)
, Article E4. 10.3171/2016.8.FOCUS16307.
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Apps, JR;
Stache, C;
Gonzalez-Meljem, JM;
Gutteridge, A;
Chalker, J;
Jacques, TS;
Forshew, T;
... Martinez-Barbera, JP; + view all
(2020)
CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma.
Neuropathology and Applied Neurobiology
, 46
(5)
pp. 510-514.
10.1111/nan.12613.
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Boult, JKR;
Apps, JR;
Hölsken, A;
Hutchinson, JC;
Carreno, G;
Danielson, LS;
Smith, LM;
... Robinson, SP; + view all
(2017)
Preclinical transgenic and patient-derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma.
Brain Pathology
10.1111/bpa.12525.
(In press).
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Carreno, G;
Boult, JKR;
Apps, JR;
Gonzalez-Meljem, JM;
Haston, S;
Guiho, R;
Stache, C;
... Martinez-Barbera, JP; + view all
(2019)
SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma.
Endocrine-Related Cancer
, 26
(3)
pp. 355-366.
10.1530/ERC-18-0538.
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Cresswell, GD;
Apps, JR;
Chagtai, T;
Mifsud, B;
Bentley, CC;
Maschietto, M;
Popov, SD;
... Mifsud, W; + view all
(2016)
Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications.
EBioMedicine
, 9
pp. 120-129.
10.1016/j.ebiom.2016.05.029.
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Fuentes-Fayos, AC;
G-García, ME;
Sánchez-Medianero, T;
Apps, J;
Flores-Martínez, Á;
De la Rosa-Herencia, AS;
Gil-Duque, I;
... Luque, RM; + view all
(2025)
Impaired splicing machinery in craniopharyngiomas unveils PRPF8 and RAVER1 as novel biomarkers and therapeutic targets.
Acta Neuropathologica Communications
, 13
(1)
p. 142.
10.1186/s40478-025-02040-w.
(In press).
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Gonzalez-Meljem, JM;
Apps, JR;
Fraser, HC;
Martinez-Barbera, JP;
(2018)
Paracrine roles of cellular senescence in promoting tumourigenesis.
British Journal of Cancer
, 118
pp. 1283-1288.
10.1038/s41416-018-0066-1.
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Gonzalez-Meljem, JM;
Haston, S;
Carreno, G;
Apps, J;
Pozzi, S;
Stache, C;
Kaushal, G;
... Martinez-Barbera, JP; + view all
(2017)
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.
Nature Communications
, 8
, Article 1819. 10.1038/s41467-017-01992-5.
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Haston, S;
Pozzi, S;
Carreno, G;
Manshaei, S;
Panousopoulos, L;
Gonzalez-Meljem, JM;
Apps, JR;
... Martinez-Barbera, JP; + view all
(2017)
MAPK pathway activation in the embryonic pituitary results in stem cell compartment expansion, differentiation defects and provides insights into the pathogenesis of papillary craniopharyngioma.
Development
, 144
pp. 2141-2152.
10.1242/dev.150490.
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Martinez-Barbera, J;
(2019)
Genetic Deletion of Hesx1 Promotes Exit from the Pluripotent State and Impairs Developmental Diapause.
Stem Cell Reports
, 13
(6)
pp. 970-979.
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Martinez-Barbera, JP;
(2017)
Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors.
Development
, 144
(18)
pp. 3289-3302.
10.1242/dev.153387.
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Martinez-Barbera, JP;
(2017)
Molecular analyses reveal inflammatory mediators in the solid component and cyst fluid of human adamantinomatous craniopharyngioma.
Journal of Neuropathology and Experimental Neurology
, 76
(9)
pp. 779-788.
10.1093/jnen/nlx061.
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Stone, TJ;
Keeley, A;
Virasami, A;
Harkness, W;
Tisdall, M;
Izquierdo Delgado, E;
Gutteridge, A;
... Jacques, TS; + view all
(2018)
Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours.
Acta Neuropathologica
, 135
(1)
pp. 115-129.
10.1007/s00401-017-1773-z.
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Vujanic, GM;
Apps, JR;
Moroz, V;
Ceroni, F;
Williams, RD;
Sebire, NJ;
Pritchard-Jones, K;
(2017)
Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience.
Pediatric Blood and Cancer
, 64
(11)
, Article e26547. 10.1002/pbc.26547.
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Xekouki, P;
Lodge, EJ;
Matschke, J;
Santambrogio, A;
Apps, JR;
Sharif, A;
Jacques, TS;
... Andoniadou, C; + view all
(2019)
Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ.
Endocrine-Related Cancer
, 26
(1)
pp. 215-225.
10.1530/ERC-18-0330.
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Thesis
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Apps, John Richard;
(2018)
Molecular characterisation of childhood craniopharyngioma and identification and testing of novel drug targets.
Doctoral thesis (Ph.D), UCL (University College London).
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