Browse by UCL people
Group by: Type | Date
Number of items: 13.
Article
Fernando, O;
Tagalakis, AD;
Shiekh Hassan Awwad, S;
Brocchini, S;
Khaw, PT;
Hart, S;
Yu-Wai-Man, C;
(2018)
Development of targeted siRNA nanocomplexes to prevent fibrosis in experimental glaucoma filtration surgery.
Molecular Therapy
, 26
(12)
pp. 2812-2822.
10.1016/j.ymthe.2018.09.004.
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Tagalakis, AD;
Madaan, S;
Larsen, SD;
Neubig, RR;
Khaw, PT;
Rodrigues, I;
Goyal, S;
... Yu-Wai-Man, C; + view all
(2018)
In vitro and in vivo delivery of a sustained release nanocarrier-based formulation of an MRTF/SRF inhibitor in conjunctival fibrosis.
Journal of Nanobiotechnology
, 16
(97)
10.1186/s12951-018-0425-3.
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Tagalakis, AD;
Maeshima, R;
Yu-Wai-Man, C;
Meng, J;
Syed, F;
Wu, LP;
Aldossary, AM;
... Hart, SL; + view all
(2017)
Peptide and nucleic acid-directed self-assembly of cationic nanovehicles through giant unilamellar vesicle modification: targetable nanocomplexes for in vivo nucleic acid delivery.
Acta Biomaterialia
10.1016/j.actbio.2017.01.048.
(In press).
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Yu Wai Man, C;
Khaw, PT;
(2015)
Developing novel anti-fibrotic therapeutics to modulate post-surgical wound healing in Glaucoma: big potential for small molecules.
Expert Review of Ophthalmology
, 10
(1)
pp. 65-76.
10.1586/17469899.2015.983475.
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Yu Wai Man, C;
Tagalakis, AD;
Meng, JH;
Bouremel, Y;
Lee, RM;
Virasami, A;
Hart, SL;
(2017)
Genotype-Phenotype Associations of IL6 and PRG4 With Conjunctival Fibrosis After Glaucoma Surgery.
JAMA Ophthalmology
, 135
(11)
pp. 1147-1155.
10.1001/jamaophthalmol.2017.3407.
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Yu-Wai-Man, C;
Arno, G;
Brookes, J;
Garcia-Feijoo, J;
Khaw, PT;
Moosajee, M;
(2018)
Primary congenital glaucoma including next-generation sequencing-based approaches: clinical utility gene card.
European Journal of Human Genetics
, 26
pp. 1713-1718.
10.1038/s41431-018-0227-y.
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Yu-Wai-Man, C;
Khaw, PT;
(2016)
Personalized Medicine in Ocular Fibrosis: Myth or Future Biomarkers.
Advances in Wound Care
, 5
(9)
pp. 390-402.
10.1089/wound.2015.0677.
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Yu-Wai-Man, C;
Lee, R;
Larsen, S;
Neubig, R;
Khaw, PT;
(2016)
Novel MRTF/SRF inhibitors prevent conjunctival scarring after glaucoma filtration surgery: An ex vivo and in vivo study.
Investigative Ophthalmology & Visual Science
, 57
(12)
, Article 2927.
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Yu-Wai-Man, C;
Owen, N;
Lees, J;
Tagalakis, AD;
Hart, SL;
Webster, AR;
Orengo, CA;
(2017)
Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery.
Scientific Reports
, 7
, Article 5644. 10.1038/s41598-017-05780-5.
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Yu-Wai-Man, C;
Spencer-Dene, B;
Lee, RMH;
Hutchings, K;
Lisabeth, EM;
Treisman, R;
Bailly, M;
... Khaw, PT; + view all
(2017)
Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis.
Scientific Reports
, 7
p. 518.
10.1038/s41598-017-00212-w.
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Yu-Wai-Man, C;
Tagalakis, AD;
Manunta, MD;
Hart, SL;
Khaw, PT;
(2016)
Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis.
Scientific Reports
, 6
, Article 21881. 10.1038/srep21881.
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Conference item
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Yu-Wai-Man, C;
Fernando, O;
Tagalakis, A;
Hart, S;
Khaw, PT;
(2018)
Development of targeted siRNA nanotherapeutics to prevent fibrosis in experimental glaucoma filtration surgery.
Presented at: ARVO Annual Meeting 2018, Honolulu, Hawaii.
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Thesis
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Yu Wai Man, CYOL;
(2017)
Targeting the Myocardin-related transcription factor / serum response factor (MRTF/SRF) pathway in conjunctival fibrosis.
Doctoral thesis , UCL (University College London).
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