Browse by UCL Departments and Centres
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Number of items: 41.
Article
Asghar, US;
Kanani, R;
Roylance, R;
Mittnacht, S;
(2022)
Systematic Review of Molecular Biomarkers Predictive of Resistance to CDK4/6 Inhibition in Metastatic Breast Cancer.
JCO Precision Oncology
, 6
pp. 1-13.
10.1200/po.21.00002.
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Berndt, Sonja I;
Vijai, Joseph;
Benavente, Yolanda;
Camp, Nicola J;
Nieters, Alexandra;
Wang, Zhaoming;
Smedby, Karin E;
... Rothman, Nathaniel; + view all
(2022)
Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.
Leukemia
, 36
(12)
pp. 2835-2844.
10.1038/s41375-022-01711-0.
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Bolik, J;
Krause, F;
Stevanovic, M;
Gandraß, M;
Thomsen, I;
Schacht, S-S;
Rieser, E;
... Schmidt-Arras, D; + view all
(2022)
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
J Exp Med
, 219
(1)
, Article e20201039. 10.1084/jem.20201039.
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Bonsor, Daniel A;
Alexander, Patrick;
Snead, Kelly;
Hartig, Nicole;
Drew, Matthew;
Messing, Simon;
Finci, Lorenzo I;
... Simanshu, Dhirendra K; + view all
(2022)
Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Nature Structural and Molecular Biology
, 29
(10)
pp. 966-977.
10.1038/s41594-022-00841-4.
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Breeze, CE;
Beck, S;
Berndt, SI;
Franceschini, N;
(2022)
The missing diversity in human epigenomic studies.
Nature Genetics
, 54
pp. 737-739.
10.1038/s41588-022-01081-4.
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Breeze, CE;
Haugen, E;
Reynolds, A;
Teschendorff, A;
van Dongen, J;
Lan, Q;
Rothman, N;
... Berndt, SI; + view all
(2022)
Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations.
Genome Biololgy
, 23
(1)
, Article 13. 10.1186/s13059-021-02560-3.
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Breeze, Charles E;
Wong, Jason YY;
Beck, Stephan;
Berndt, Sonja I;
Franceschini, Nora;
(2022)
Diversity in EWAS: current state, challenges, and solutions.
Genome Medicine
, 14
, Article 71. 10.1186/s13073-022-01065-3.
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Brooks, Lucy J;
Clements, Melanie P;
Burden, Jemima J;
Kocher, Daniela;
Richards, Luca;
Devesa, Sara Castro;
Zakka, Leila;
... Parrinello, Simona; + view all
(2022)
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Nature Communications
, 13
(1)
, Article 2163. 10.1038/s41467-022-29916-y.
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Brooks, Lucy J;
Simpson Ragdale, Holly;
Hill, Ciaran Scott;
Clements, Melanie;
Parrinello, Simona;
(2022)
Injury programs shape glioblastoma.
Trends in Neurosciences
10.1016/j.tins.2022.08.006.
(In press).
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Cardenas, Andres;
Ecker, Simone;
Fadadu, Raj P;
Huen, Karen;
Orozco, Allan;
McEwen, Lisa M;
Engelbrecht, Hannah-Ruth;
... Rehkopf, David H; + view all
(2022)
Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults.
Scientific Reports
, 12
, Article 4277. 10.1038/s41598-022-08160-w.
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Chakravarthy, Ankur;
Reddin, Ian;
Henderson, Stephen;
Dong, Cindy;
Kirkwood, Nerissa;
Jeyakumar, Maxmilan;
Rodriguez, Daniela Rothschild;
... Fenton, Tim R; + view all
(2022)
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.
Nature Communications
, 13
, Article 5818. 10.1038/s41467-022-33544-x.
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Chervova, Olga;
Chernysheva, Elizabeth;
Panteleeva, Kseniia;
Widayati, Tyas Arum;
Hrbkova, Natalie;
Schneider, Jadesada;
Maximov, Vladimir;
... Beck, Stephan; + view all
(2022)
Evaluation of Epigenetic Age Acceleration Scores and Their Associations with CVD-Related Phenotypes in a Population Cohort.
Biology
, 12
(1)
, Article 68. 10.3390/biology12010068.
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Cottone, Lucia;
Ligammari, Lorena;
Lee, Hang-Mao;
Knowles, Helen J;
Henderson, Stephen;
Bianco, Sara;
Davies, Christopher;
... Flanagan, Adrienne M; + view all
(2022)
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cell Death & Differentiation
, 29
pp. 2459-2471.
10.1038/s41418-022-01031-x.
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Dupras, Charles;
Knoppers, Terese;
Palmour, Nicole;
Beauchamp, Elisabeth;
Liosi, Stamatina;
Siebert, Reiner;
Berner, Alison May;
... Joly, Yann; + view all
(2022)
Researcher perspectives on ethics considerations in epigenetics: an international survey.
Clinical Epigenetics
, 14
(1)
, Article 110. 10.1186/s13148-022-01322-7.
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Engelbrecht, Hannah-Ruth;
Merrill, Sarah M;
Gladish, Nicole;
MacIsaac, Julie L;
Lin, David TS;
Ecker, Simone;
Chrysohoou, Christina A;
... Rehkopf, David H; + view all
(2022)
Sex differences in epigenetic age in Mediterranean high longevity regions.
Frontiers in Aging
, 3
, Article 1007098. 10.3389/fragi.2022.1007098.
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Fernandes, Liane P;
Enriquez-Gasca, Rocio;
Gould, Poppy A;
Holt, James H;
Conde, Lucia;
Ecco, Gabriela;
Herrero, Javier;
... Rowe, Helen M; + view all
(2022)
A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819.
Science Advances
, 8
(43)
, Article eabp8085. 10.1126/sciadv.abp8085.
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Geron, Ifat;
Savino, Angela Maria;
Fishman, Hila;
Tal, Noa;
Brown, John;
Turati, Virginia A;
James, Chela;
... Izraeli, Shai; + view all
(2022)
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia.
Nature Communications
, 13
, Article 659. 10.1038/s41467-022-28218-7.
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Hertweck, Arnulf;
Vila de Mucha, Maria;
Barber, Paul R;
Dagil, Robert;
Porter, Hayley;
Ramos, Andres;
Lord, Graham M;
(2022)
The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes.
Nucleic Acids Research
, Article gkac258. 10.1093/nar/gkac258.
(In press).
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Huerne, Katherine;
Palmour, Nicole;
Wu, Angela Ruohao;
Beck, Stephan;
Berner, Alison;
Siebert, Reiner;
Joly, Yann;
(2022)
Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing.
The CRISPR Journal
10.1089/crispr.2021.0094.
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Kleijn, Istvan T;
Martínez-Segura, Amalia;
Bertaux, François;
Saint, Malika;
Kramer, Holger;
Shahrezaei, Vahid;
Marguerat, Samuel;
(2022)
Growth-rate-dependent and nutrient-specific gene expression resource allocation in fission yeast.
Life Science Alliance
, 5
(5)
, Article e202101223. 10.26508/lsa.202101223.
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Lechner, M;
Takahashi, Y;
Turri-Zanoni, M;
Liu, J;
Counsell, N;
Hermsen, M;
Kaur, RP;
... Hanna, EY; + view all
(2022)
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma.
European Journal of Cancer
, 162
pp. 221-236.
10.1016/j.ejca.2021.09.046.
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Li, Xiang;
Huang, Chun-Hao;
Sánchez-Rivera, Francisco J;
Kennedy, Margaret C;
Tschaharganeh, Darjus F;
Morris, John P;
Montinaro, Antonella;
... Lowe, Scott W; + view all
(2022)
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Proceedings of the National Academy of Sciences
, 119
(17)
, Article e2110557119. 10.1073/pnas.2110557119.
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Lyskjær, Iben;
Kara, Neesha;
De Noon, Solange;
Davies, Christopher;
Rocha, Ana Maia;
Strobl, Anna-Christina;
Usher, Inga;
... Flanagan, Adrienne M; + view all
(2022)
Osteosarcoma: Novel prognostic biomarkers using circulating and cell-free tumour DNA.
European Journal of Cancer
, 168
pp. 1-11.
10.1016/j.ejca.2022.03.002.
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Malyutina, S;
Chervova, O;
Tillmann, T;
Maximov, V;
Ryabikov, A;
Gafarov, V;
Hubacek, JA;
... Bobak, M; + view all
(2022)
The Relationship between Epigenetic Age and Myocardial Infarction/Acute Coronary Syndrome in a Population-Based Nested Case-Control Study.
Journal of Personalized Medicine
, 12
(1)
p. 110.
10.3390/jpm12010110.
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Montinaro, Antonella;
Walczak, Henning;
(2022)
Harnessing TRAIL-induced cell death for cancer therapy: a long walk with thrilling discoveries.
Cell Death & Differentiation
10.1038/s41418-022-01059-z.
(In press).
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Omer, Omer S;
Hertweck, Arnulf;
Roberts, Luke B;
Lo, Jonathan W;
Clough, Jennie N;
Jackson, Ian;
Pantazi, Eirini D;
... Lord, Graham M; + view all
(2022)
Cyclin-dependent kinase 9 as a potential target for anti-TNF resistant inflammatory bowel disease.
Cellular and Molecular Gastroenterology and Hepatology
10.1016/j.jcmgh.2022.05.011.
(In press).
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Petricevic, Branka;
Kabiljo, Julijan;
Zirnbauer, Rebecca;
Walczak, Henning;
Laengle, Johannes;
Bergmann, Michael;
(2022)
Neoadjuvant immunotherapy in gastrointestinal cancers - The new standard of care?
Seminars in Cancer Biology
, 86
(Pt 2)
pp. 834-850.
10.1016/j.semcancer.2022.05.015.
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Rodriguez-Lopez, Maria;
Anver, Shajahan;
Cotobal, Cristina;
Kamrad, Stephan;
Malecki, Michal;
Correia-Melo, Clara;
Hoti, Mimoza;
... Bähler, Jürg; + view all
(2022)
Correction: Functional profiling of long intergenic non-coding RNAs in fission yeast.
[Corrigendum].
eLife
, 11
, Article e77337. 10.7554/eLife.77337.
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Tanić, Miljana;
Moghul, Ismail;
Rodney, Simon;
Dhami, Pawan;
Vaikkinen, Heli;
Ambrose, John;
Barrett, James;
... Beck, Stephan; + view all
(2022)
Comparison and imputation-aided integration of five commercial platforms for targeted DNA methylome analysis.
Nature Biotechnology
, 40
pp. 1478-1487.
10.1038/s41587-022-01336-9.
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Tavares, Manuel;
Khandelwal, Garima;
Muter, Joanne;
Viiri, Keijo;
Beltran, Manuel;
Brosens, Jan J;
Jenner, Richard G;
(2022)
JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation.
Cell Reports
, 39
(9)
, Article 110889. 10.1016/j.celrep.2022.110889.
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Theobald, Sebastian J;
Simonis, Alexander;
Mudler, Julie M;
Goebel, Ulrike;
Acton, Richard;
Kohlhas, Viktoria;
Albert, Marie-Christine;
... Rybniker, Jan; + view all
(2022)
Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS-CoV-2 mRNA vaccination.
EMBO Molecular Medicine
, 14
(8)
, Article e15888. 10.15252/emmm.202215888.
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Vesely, Clare;
Wong, Yien Ning Sophia;
Childs, Alexa;
Akarca, Ayse U;
Dhami, Pawan;
Vaikkinen, Heli;
Conde, Lucia;
... Meyer, Tim; + view all
(2022)
Systematic Evaluation of the Immune Environment of Small Intestinal Neuroendocrine Tumours.
Clinical Cancer Research
10.1158/1078-0432.CCR-21-4203.
(In press).
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Webster, Amy P;
Ecker, Simone;
Moghul, Ismail;
Dhami, Pawan;
Marzi, Sarah;
Paul, Dirk S;
Kuxhausen, Michelle;
... Beck, Stephan; + view all
(2022)
Donor whole blood DNA methylation is not a strong predictor of acute graft versus host disease in unrelated donor allogeneic haematopoietic cell transplantation.
medRxiv
10.1101/2022.03.08.22272071.
(In press).
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Wray, Jason P;
Deltcheva, Elitza M;
Boiers, Charlotta;
Richardson, Simon Е;
Chhetri, Jyoti Bikram;
Brown, John;
Gagrica, Sladjana;
... Enver, Tariq; + view all
(2022)
Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability.
Nature Communications
, 13
, Article 7124. 10.1038/s41467-022-34653-3.
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Zhang, Xiaoyan;
Yang, Ling;
Lei, Wanjun;
Hou, Qiang;
Huang, Ming;
Zhou, Rongjing;
Enver, Tariq;
(2022)
Single-cell sequencing reveals CD133+CD44--originating evolution and novel stemness related variants in human colorectal cancer.
EBioMedicine
, 82
, Article 104125. 10.1016/j.ebiom.2022.104125.
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Zhu, Tianyu;
Liu, Jacklyn;
Beck, Stephan;
Pan, Sun;
Capper, David;
Lechner, Matt;
Thirlwell, Chrissie;
... Teschendorff, Andrew E; + view all
(2022)
A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution.
Nature Methods
, 19
pp. 296-306.
10.1038/s41592-022-01412-7.
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Zinngrebe, Julia;
Moepps, Barbara;
Monecke, Thomas;
Gierschik, Peter;
Schlichtig, Ferdinand;
Barth, Thomas FE;
Strauß, Gudrun;
... Debatin, Klaus-Michael; + view all
(2022)
Compound heterozygous variants in OTULIN are associated with fulminant atypical late-onset ORAS.
EMBO Molecular Medicine
, 14
(3)
, Article e14901. 10.15252/emmm.202114901.
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Working / discussion paper
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Amodeo, Valeria;
Davies, Timothy;
Martinez-Segura, Amalia;
Clements, Melanie;
Ragdale, Holly Simpson;
Bailey, Andrew;
Silva Dos Santos, Mariana;
... Parrinello, Simona; + view all
(2022)
Diet suppresses tumour initiation by maintaining quiescence of mutation-bearing neural stem cells.
bioRxiv: Cold Spring Harbor, NY, USA.
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Thesis
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Garcia Diaz, Claudia;
(2022)
Novel de novo Glioblastoma mouse models reveal differences in the biology of the tumour bulk and invasive margin.
Doctoral thesis (Ph.D), UCL (University College London).
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Nyoni, Lynet;
(2022)
Targeting the tumour microenvironment through death ligand inhibition.
Doctoral thesis (Ph.D), UCL (University College London).
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Weeks, Samuel Luke;
(2022)
Characterisation of the roles of Stag paralogs in transitions of pluripotency.
Doctoral thesis (Ph.D), UCL (University College London).
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