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Practical aspects of a data-driven motion correction approach for brain SPECT

Kyme, A.Z.; Hutton, B.F.; Hatton, R.L.; Skerrett, D.W.; Barnden, L.R.; (2003) Practical aspects of a data-driven motion correction approach for brain SPECT. IEEE Transactions on Medical Imaging , 22 (6) pp. 722-729. 10.1109/TMI.2003.814790. Green open access

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Patient motion can cause image artifacts in single photon emission computed tomography despite restraining measures. Data-driven detection and correction of motion can be achieved by comparison of acquired data with the forward projections. This enables the brain locations to be estimated and data to be correctly incorporated in a three-dimensional (3-D) reconstruction algorithm. Digital and physical phantom experiments were performed to explore practical aspects of this approach. Noisy simulation data modeling multiple 3-D patient head movements were constructed by projecting the digital Hoffman brain phantom at various orientations. Hoffman physical phantom data incorporating deliberate movements were also gathered. Motion correction was applied to these data using various regimes to determine the importance of attenuation and successive iterations. Studies were assessed visually for artifact reduction, and analyzed quantitatively via a mean registration error (MRE) and mean square difference measure (MSD). Artifacts and distortion in the motion corrupted data were reduced to a large extent by application of this algorithm. MRE values were mostly well within 1 pixel (4.4 mm) for the simulated data. Significant MSD improvements (>2) were common. Inclusion of attenuation was unnecessary to accurately estimate motion, doubling the efficiency and simplifying implementation. Moreover, most motion-related errors were removed using a single iteration. The improvement for the physical phantom data was smaller, though this may be due to object symmetry. In conclusion, these results provide the basis of an implementation protocol for clinical validation of the technique.

Type: Article
Title: Practical aspects of a data-driven motion correction approach for brain SPECT
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/TMI.2003.814790
Publisher version: http://dx.doi.org/10.1109/TMI.2003.814790
Language: English
Additional information: ©2003 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/9643
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