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Combined EEG-fMRI and tractography to visualise propagation of epileptic activity

Hamandi, K.; Powell, H.W.R.; Laufs, H.; Symms, M.R.; Barker, G.J.; Parker, G.J.M.; Lemieux, L.; (2008) Combined EEG-fMRI and tractography to visualise propagation of epileptic activity. Journal of Neurology, Neurosurgery and Psychiatry , 79 (5) pp. 594-597. 10.1136/jnnp.2007.125401. Green open access

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Abstract

In a patient with refractory temporal lobe epilepsy, EEG-fMRI showed activation in association with left anterior temporal interictal discharges, in the left temporal, parietal and occipital lobes. Dynamic causal modelling suggested propagation of neural activity from the temporal focus to the area of occipital activation. Tractography showed connections from the site of temporal lobe activation to the site of occipital activation. This demonstrates the principle of combining EEG-fMRI and tractography to delineate the pathways of propagation of epileptic activity.

Type: Article
Title: Combined EEG-fMRI and tractography to visualise propagation of epileptic activity
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/jnnp.2007.125401
Publisher version: http://dx.doi.org/10.1136/jnnp.2007.125401
Language: English
Additional information: Article reproduced here under the terms and conditions of the Creative Commons Attribution Non Commercial 2.0 licence and specifically prohibits commercial use of these articles. For more information please see: http://creativecommons.org/licenses/by-nc/2.0/
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy
URI: https://discovery.ucl.ac.uk/id/eprint/20274
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