Papadimitriou, K;
Evans, D;
Morgan, H;
A PCB-based electronic ELISA system for rapid, portable infectious disease diagnosis.
In: Lian, Y and Land, TS and Wang, Z, (eds.)
Proceedings of IEEE Biomedical Circuits and Systems Conference (BioCAS), 2016.
(pp. pp. 252-255).
Biomedical Circuits and Systems Conference (BioCAS): Shanghai, China.
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Abstract
In this paper an amperometric electrochemical detection method is demonstrated and implemented using exclusively Printed Circuit Board (PCB)-based technologies. A portable, reconfigurable, multichannel amperometric data-acquisition board has been designed and fabricated, dedicated to the measurement of current-input signals delivered by the PCB-based biosensor. The electronic read-out circuit is able to provide constant biasing voltages to the amperometric sensor, measure in real-time the sensor's output currents, digitise them using high-accuracy Analog-to-Digital Converters (ADCs) and send the binary data to the user either through a USB2.0 interface or via an on-board TFT touch-screen. In order to validate the robustness and accuracy of the combined system, proof-of-concept amperometric experiments have taken place using our custom-made PCB-based system and standard electrochemical substrates. The results obtained have been cross-validated by means of standard colorimetric analysis and their differences have been highlighted and analyzed.
| Type: | Proceedings paper |
|---|---|
| Title: | A PCB-based electronic ELISA system for rapid, portable infectious disease diagnosis |
| Event: | IEEE Biomedical Circuits and Systems Conference (BioCAS), 2016 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/BioCAS.2016.7833779 |
| Publisher version: | https://doi.org/10.1109/BioCAS.2016.7833779 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| Keywords: | Current measurement, Standards, Sensitivity, Electrodes, Voltage measurement, Gold, Protocols |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1556154 |
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