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Sitting behaviour is not associated with incident diabetes over 13 years: the Whitehall II cohort study

Stamatakis, E; Pulsford, RM; Brunner, EJ; Britton, AR; Bauman, AE; Biddle, SJ; Hillsdon, M; (2017) Sitting behaviour is not associated with incident diabetes over 13 years: the Whitehall II cohort study. British Journal of Sports Medicine , 51 (10) pp. 818-823. 10.1136/bjsports-2016-096723. Green open access

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Abstract

BACKGROUND: Although certain types of sedentary behaviour have been linked to metabolic risk, prospective studies describing the links between sitting with incident diabetes are scarce and often do not account for baseline adiposity. We investigate the associations between context-specific sitting and incident diabetes in a cohort of mid-aged to older British civil servants. METHODS: Using data from the Whitehall II study (n=4811), Cox proportional hazards models (adjusted for age, sex, ethnicity, employment grade, smoking, alcohol intake, fruit and vegetable consumption, self-rated health, physical functioning, walking and moderate-to-vigorous physical activity, and body mass index (BMI)) were fitted to examine associations between total sitting and context–specific sitting time (work, television (TV), non-TV leisure time sitting at home) at phase 5 (1997–1999) and fasting glucose-defined incident diabetes up to 2011. RESULTS: Total sitting (HR of the top compared with the bottom group: 1.26; 95% CI 1.00 to 1.62; p=0.01) and TV sitting (1.33; 95% CI 1.03 to 1.88; p=0.05) showed associations with incident diabetes; once BMI was included in the model these associations were attenuated for both total sitting (1.19; 95% CI 0.92 to 1.55; p=0.22) and TV sitting (1.31; 95% CI 0.96 to 1.76; p=0.14). CONCLUSION: We found limited evidence linking sitting and incident diabetes over 13 years in this occupational cohort of civil servants.

Type: Article
Title: Sitting behaviour is not associated with incident diabetes over 13 years: the Whitehall II cohort study
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/bjsports-2016-096723
Publisher version: http://doi.org/10.1136/bjsports-2016-096723
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: diabetes, cardiometabolic, sedentary behaviour, sitting, physical activity, epidemiology, public health, prevention
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/1555479
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