Sudre, CH;
Cardoso, MJ;
Ourselin, S;
(2017)
Longitudinal segmentation of age-related white matter hyperintensities.
MEDICAL IMAGE ANALYSIS
, 38
pp. 50-64.
10.1016/j.media.2017.02.007.
Abstract
Although white matter hyperintensities evolve in the course of ageing, few solutions exist to consider the lesion segmentation problem longitudinally. Based on an existing automatic lesion segmentation algorithm, a longitudinal extension is proposed. For evaluation purposes, a longitudinal lesion simulator is created allowing for the comparison between the longitudinal and the cross-sectional version in various situations of lesion load progression. Finally, applied to clinical data, the proposed framework demonstrates an increased robustness compared to available cross-sectional methods and findings are aligned with previously reported clinical patterns.
| Type: |
Article
|
| Title: |
Longitudinal segmentation of age-related white matter hyperintensities |
| Open access status: |
An open access version is available from UCL Discovery |
| DOI: |
10.1016/j.media.2017.02.007 |
| Publisher version: |
http://dx.doi.org/10.1016/j.media.2017.02.007 |
| Language: |
English |
| Additional information: |
© 2017 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| Keywords: |
Science & Technology, Technology, Life Sciences & Biomedicine, Computer Science, Artificial Intelligence, Computer Science, Interdisciplinary Applications, Engineering, Biomedical, Radiology, Nuclear Medicine & Medical Imaging, Computer Science, Engineering, White matter hyperintensities, Segmentation, Longitudinal, MULTIPLE-SCLEROSIS LESIONS, BRAIN MRI, PROGRESSION, VOLUME, LEUKOARAIOSIS, DECLINE, IMAGES |
| UCL classification: |
UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine > MRC Unit for Lifelong Hlth and Ageing
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: |
https://discovery.ucl.ac.uk/id/eprint/1551441 |
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