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Reperfusion, conditioning and the ongoing search for the holy grail

Yellon, RL; Bell, RM; (2017) Reperfusion, conditioning and the ongoing search for the holy grail. The British Journal of Cardiology , 24 (1) pp. 35-38. 10.5837/bjc.2017.008. Green open access

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Abstract

schaemic conditioning is the phenomenon of protection against reperfusion injury via the application of brief, repeated episodes of non-lethal ischaemia. This review has three aims: 1) to briefly explain the various categories of ischaemic conditioning; 2) to explore past clinical trials and their failures; 3) to explore the future of clinical trials in the realm of ischaemic conditioning.

Type: Article
Title: Reperfusion, conditioning and the ongoing search for the holy grail
Open access status: An open access version is available from UCL Discovery
DOI: 10.5837/bjc.2017.008
Publisher version: http://dx.doi.org/10.5837/bjc.2017.008
Language: English
Additional information: © 2017 The British Journal of Cardiology.
Keywords: Ischaemic conditioning, per-conditioning, post-conditioning, pre-conditioning, reperfusion injury
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Pre-clinical and Fundamental Science
URI: https://discovery.ucl.ac.uk/id/eprint/1549601
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