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A joint-reconstruction approach for single-shot edge illumination x-ray phase-contrast tomography

Chen, Y; Guan, H; Hagen, CK; Olivo, A; Anastasio, MA; (2017) A joint-reconstruction approach for single-shot edge illumination x-ray phase-contrast tomography. In: Flohr, TG and Lo, JY and Schmidt, TG, (eds.) Medical Imaging 2017: Physics of Medical Imaging. (pp. 1013217-1-1013217-6). Society of Photo-Optical Instrumentation Engineers (SPIE) Green open access

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Abstract

Edge illumination X-ray phase-contrast tomography (EIXPCT) is an imaging technique that estimates the spatially variant X-ray refractive index and absorption distribution within an object while seeking to circumvent the limitations of previous benchtop implementations of X-ray phase-contrast tomography. As with gratingor analyzer-based methods, conventional image reconstruction methods for EIXPCT require that two or more images be acquired at each tomographic view angle. This requirement leads to increased data acquisition times, hindering in vivo applications. To circumvent these limitations, a joint reconstruction (JR) approach is proposed that concurrently produces estimates of the refractive index and absorption distributions from a tomographic data set containing only a single image per tomographic view angle. The JR reconstruction method solves a nonlinear optimization problem by use of a novel iterative gradient-based algorithm. The JR method is demonstrated in both computer-simulated and experimental EIXPCT studies.

Type: Proceedings paper
Title: A joint-reconstruction approach for single-shot edge illumination x-ray phase-contrast tomography
Event: Medical Imaging 2017: 13-16 February 2017, Orlando, Florida, USA
Location: Orlando, Florida, US
Dates: 11 February 2017 - 16 February 2017
ISBN-13: 9781510607095
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/12.2255545
Publisher version: http://dx.doi.org/10.1117/12.2255545
Language: English
Additional information: This is the published version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Joint reconstruction, phase-contrast imaging, single-shot imaging
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1545664
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