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The global dynamics of diabetes and tuberculosis: the impact of migration and policy implications

Girardi, E; Schepisi, MS; Goletti, D; Bates, M; Mwaba, P; Yeboah-Manu, D; Ntoumi, F; ... Ippolito, G; + view all (2017) The global dynamics of diabetes and tuberculosis: the impact of migration and policy implications. International Journal of Infectious Diseases , 56 pp. 45-53. 10.1016/j.ijid.2017.01.018. Green open access

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Abstract

The convergence between tuberculosis (TB) and diabetes mellitus (DM) will represent a major public health challenge in the near future. DM increases the risk of developing TB by two to three times and also increases the risk of TB treatment failure, relapse, and death. The global prevalence of DM is predicted to rise significantly in the next two decades, particularly in some of the low- and middle-income countries with the highest TB burden. Migration may add further complexity to the effort to control the impact on TB of the growing DM pandemic. Migration may increase the risk of DM, although the magnitude of this association varies according to country of origin and ethnic group, due to genetic factors and lifestyle differences. Migrants with TB may have an increased prevalence of DM compared to the native population, and the risk of TB among persons with DM may be higher in migrants than in autochthonous populations. Screening for DM among migrants, screening migrants with DM for active and latent TB, and improving access to DM care, could contribute to mitigate the effects of DM on TB.

Type: Article
Title: The global dynamics of diabetes and tuberculosis: the impact of migration and policy implications
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ijid.2017.01.018
Publisher version: http://doi.org/10.1016/j.ijid.2017.01.018
Language: English
Additional information: © 2017 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: Science & Technology, Life Sciences & Biomedicine, Infectious Diseases, Tuberculosis, Diabetes, Communicable diseases, Migrants, MYCOBACTERIUM-TUBERCULOSIS, PULMONARY TUBERCULOSIS, RISK-FACTORS, EPIDEMIOLOGIC TRANSITION, CARDIOVASCULAR-DISEASE, INSULIN-RESISTANCE, PROSPECTIVE COHORT, METABOLIC SYNDROME, PACIFIC ISLANDERS, GLYCEMIC CONTROL
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/1540742
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