Baheerathan, A;
Brownlee, WJ;
Chard, DT;
Shields, K;
Gregory, R;
Trip, SA;
(2017)
Antecedent anti-NMDA receptor encephalitis in two patients with multiple sclerosis.
Multiple Sclerosis and Related Disorders
, 12
pp. 20-22.
10.1016/j.msard.2016.12.009.
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Abstract
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disorder characterised by psychiatric symptoms, movement disorder and seizures often evolving into a severe encephalopathy. An overlap has recently been recognised between anti-NMDAR encephalitis and inflammatory demyelinating disorders, particularly neuromyelitis optical spectrum disorder (NMOSD). In this case report, we describe two patients with an initial presentation consistent with anti-NMDAR encephalitis who have subsequently developed relapsing-remitting multiple sclerosis (MS) and discuss the literature pertaining to potential overlap between NMDAR encephalitis and inflammatory demyelinating disorders.
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