Thompson, A;
Marwaha, S;
Winsper, C;
Everard, L;
Jones, PB;
Fowler, D;
Amos, T;
... Birchwood, M; + view all
(2016)
Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort.
Acta Psychiatrica Scandinavica
, 134
(4)
pp. 321-328.
10.1111/acps.12623.
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Abstract
OBJECTIVE: The incidence and outcome of first-episode substance-induced psychotic disorder (SIPD) are unclear. The study aimed to compare the 1-year outcomes of those given a SIPD diagnosis by clinicians compared to other psychosis diagnoses in a first-episode cohort. METHOD: Data were from a large (n = 1027) cohort of first-episode psychosis (FEP) patients admitted to early intervention services in the UK (National EDEN). Diagnosis, including that of SIPD, was made by treating psychiatrists at baseline using ICD10 criteria. Details on symptoms, functioning, quality of life, relapse and recovery were available at baseline and 12 months. RESULTS: There were 67 cases of SIPD (6.5% of the cohort). At baseline, SIPD patients were no different to other psychoses on symptoms, functioning and quality of life. At 12 months, there was no difference in SIPD and other psychoses on functioning, quality of life or relapse and recovery rates. Levels of psychotic and general symptomatology were similar but depressive symptoms were higher in the SIPD group. CONCLUSIONS: First-episode psychosis patients with a diagnosis of SIPD do not appear to have better outcomes than those with other primary psychotic diagnoses. The higher levels of depressive symptoms may be a specific marker in these patients.
| Type: | Article |
|---|---|
| Title: | Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/acps.12623 |
| Publisher version: | http://dx.doi.org/10.1111/acps.12623 |
| Language: | English |
| Additional information: | Copyright © 2016 John Wiley & Sons A/S. This is the peer reviewed version of the following article: [Thompson, A; Marwaha, S; Winsper, C; Everard, L; Jones, PB; Fowler, D; Amos, T; (2016) Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort. Acta Psychiatrica Scandinavica, 134 (4) pp. 321-328. 10.1111/acps.12623], which has been published in final form at http://dx.doi.org/10.1111/acps.12623. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
| Keywords: | first-episode psychosis; substance-induced psychotic disorders; outcome; cohort study |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > Comprehensive CTU at UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1533427 |
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