Robinson, I;
Yang, Y;
Zhang, F;
Lynch, C;
Yusuf, M;
Cloetens, P;
(2016)
Nuclear incorporation of iron during the eukaryotic cell cycle.
Journal of Synchrotron Radiation
, 23
(6)
pp. 1490-1497.
10.1107/S1600577516012807.
Preview |
Text
fv5053.pdf - Published Version Download (919kB) | Preview |
Abstract
Scanning X-ray fluorescence microscopy has been used to probe the distribution of S, P and Fe within cell nuclei. Nuclei, which may have originated at different phases of the cell cycle, are found to show very different levels of Fe present with a strongly inhomogeneous distribution. P and S signals, presumably from DNA and associated nucleosomes, are high and relatively uniform across all the nuclei; these agree with X-ray phase contrast projection microscopy images of the same samples. Possible reasons for the Fe incorporation are discussed.
Type: | Article |
---|---|
Title: | Nuclear incorporation of iron during the eukaryotic cell cycle |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1107/S1600577516012807 |
Publisher version: | https://doi.org/10.1107/S1600577516012807 |
Language: | English |
Additional information: | This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
Keywords: | Science & Technology, Technology, Physical Sciences, Instruments & Instrumentation, Optics, Physics, Applied, Physics, Fluorecence, Beamline, Chromosome, Imaging, Phase Contrast, Human-Chromosomes, Sulfur Cluster, Dna, Microscopy, Mechanisms, Primase, Domain |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > London Centre for Nanotechnology |
URI: | https://discovery.ucl.ac.uk/id/eprint/1530674 |
Archive Staff Only
View Item |