Diemoz, PC;
Bravin, A;
Sztrókay-Gaul, A;
Ruat, M;
Grandl, S;
Mayr, D;
Auweter, S;
... Olivo, A; + view all
(2016)
A method for high-energy, low-dose mammography using edge illumination x-ray phase-contrast imaging.
Physics in Medicine and Biology
, 61
, Article 8750. 10.1088/1361-6560/61/24/8750.
![[thumbnail of Olivio_Diemoz_2016_Phys._Med._Biol._61_8750.pdf]](https://discovery.ucl.ac.uk/style/images/fileicons/text.png) |
Text
Olivio_Diemoz_2016_Phys._Med._Biol._61_8750.pdf - Published Version Download (1MB) |
Abstract
Since the breast is one of the most radiosensitive organs, mammography is arguably the area where lowering radiation dose is of the uttermost importance. Phase-based x-ray imaging methods can provide opportunities in this sense, since they do not require x-rays to be stopped in tissue for image contrast to be generated. Therefore, x-ray energy can be considerably increased compared to those usually exploited by conventional mammography. In this article we show how a novel, optimized approach can lead to considerable dose reductions. This was achieved by matching the edge-illumination phase method, which reaches very high angular sensitivity also at high x-ray energies, to an appropriate image processing algorithm and to a virtually noise-free detection technology capable of reaching almost 100% efficiency at the same energies. Importantly, while proof-of-concept was obtained at a synchrotron, the method has potential for a translation to conventional sources.
| Type: | Article |
|---|---|
| Title: | A method for high-energy, low-dose mammography using edge illumination x-ray phase-contrast imaging |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1088/1361-6560/61/24/8750 |
| Publisher version: | http://dx.doi.org/10.1088/1361-6560/61/24/8750 |
| Language: | English |
| Additional information: | Original content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1522107 |
Loading...
Loading...Loading...Loading...Archive Staff Only
 |
View Item |
