Stenner, M-P;
Duerschmid, S;
Rutledge, RB;
Zaehle, T;
Schmitt, FC;
Kaufmann, J;
Voges, J;
... Schoenfeld, MA; + view all
(2016)
Perimovement decrease of alpha/beta oscillations in the human nucleus accumbens.
Journal of Neurophysiology
, 116
(4)
pp. 1663-1672.
10.1152/jn.00142.2016.
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Abstract
The human nucleus accumbens is thought to play an important role in guiding future action selection via an evaluation of current action outcomes. Here we provide electrophysiological evidence for a more direct, i.e., online, role during action preparation. We recorded local field potentials from the nucleus accumbens in patients with epilepsy undergoing surgery for deep brain stimulation. We found a consistent decrease in the power of alpha/beta oscillations (10–30 Hz) before and around the time of movements. This perimovement alpha/beta desynchronization was observed in seven of eight patients and was present both before instructed movements in a serial reaction time task as well as before self-paced, deliberate choices in a decision making task. A similar beta decrease over sensorimotor cortex and in the subthalamic nucleus has been directly related to movement preparation and execution. Our results support the idea of a direct role of the human nucleus accumbens in action preparation and execution.
| Type: | Article |
|---|---|
| Title: | Perimovement decrease of alpha/beta oscillations in the human nucleus accumbens |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1152/jn.00142.2016 |
| Publisher version: | http://dx.doi.org/10.1152/jn.00142.2016 |
| Language: | English |
| Additional information: | Copyright © 2016 the American Physiological Society Licensed under Creative Commons Attribution CC-BY 3.0: © the American Physiological Society. |
| Keywords: | Science & Technology, Life Sciences & Biomedicine, Neurosciences, Physiology, Neurosciences & Neurology, nucleus accumbens, beta oscillations, action preparation, deep brain stimulation, MOVEMENT-RELATED CHANGES, HUMAN SUBTHALAMIC NUCLEUS, REWARD PREDICTION ERROR, HUMAN BASAL GANGLIA, DECISION-MAKING, PARKINSONS-DISEASE, INTRACRANIAL RECORDINGS, BETA-DESYNCHRONIZATION, DISSOCIABLE ROLES, MOTOR-PERFORMANCE |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1508732 |
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