Grosso, G;
Stepaniak, U;
Micek, A;
Stefler, D;
Bobak, M;
Pajak, A;
(2016)
Coffee consumption and mortality in three Eastern European countries: results from the HAPIEE (Health, Alcohol and Psychosocial factors In Eastern Europe) study.
Public Health Nutrition
10.1017/S1368980016001749.
(In press).
Preview |
Text
Stefler_coffee-consumption-and-mortality-in-three-eastern-european-countries-results-from-the-hapiee-health-alcohol-and-psychosocial-factors-in-eastern-europe-study.pdf Download (599kB) | Preview |
Abstract
OBJECTIVE: To test the association between coffee consumption and risk of all-cause, CVD and cancer death in a European cohort. DESIGN: Prospective cohort study. Cox proportional hazards models with adjustment for potential confounders to estimate multivariable hazard ratios (HR) and 95 % CI were used. SETTING: Czech Republic, Russia and Poland. SUBJECTS: A total of 28561 individuals followed for 6·1 years. RESULTS: A total of 2121 deaths (43·1 % CVD and 35·7 % cancer mortality) occurred during the follow-up. Consumption of 3-4 cups coffee/d was associated with lower mortality risk in men (HR=0·83; 95 % CI 0·71, 0·99) and women (HR=0·63; 95 % CI 0·47, 0·84), while further intake showed non-significant reduced risk estimates (HR=0·71; 95 % CI 0·49, 1·04 and HR=0·51; 95 % CI 0·24, 1·10 in men and women, respectively). Decreased risk of CVD mortality was also found in men (HR=0·71; 95 % CI 0·54, 0·93) for consumption of 3-4 cups coffee/d. Stratified analysis revealed that consumption of a similar amount of coffee was associated with decreased risk of all-cause (HR=0·61; 95 % CI 0·43, 0·87) and cancer mortality (HR=0·59; 95 % CI 0·35, 0·99) in non-smoking women and decreased risk of all-cause mortality for >4 cups coffee/d in men with no/moderate alcohol intake. CONCLUSIONS: Coffee consumption was associated with decreased risk of mortality. The protective effect was even stronger when stratification by smoking status and alcohol intake was performed.
| Type: | Article |
|---|---|
| Title: | Coffee consumption and mortality in three Eastern European countries: results from the HAPIEE (Health, Alcohol and Psychosocial factors In Eastern Europe) study |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1017/S1368980016001749 |
| Publisher version: | http://dx.doi.org/10.1017/S1368980016001749 |
| Language: | English |
| Additional information: | © The Authors 2016. The final publication is available at Cambridge University Press via http://dx.doi.org/10.1017/S1368980016001749. |
| Keywords: | Coffee, Cohort, Europe, Mortality, Prospective |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1506415 |
Archive Staff Only
 |
View Item |
