Jeong, H-H;
Mark, AG;
Alarcón-Correa, M;
Kim, I;
Oswald, P;
Lee, T-C;
Fischer, P;
(2016)
Dispersion and shape engineered plasmonic nanosensors.
Nature Communications
, 7
, Article 11331. 10.1038/ncomms11331.
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Abstract
Biosensors based on the localized surface plasmon resonance (LSPR) of individual metallic nanoparticles promise to deliver modular, low-cost sensing with high-detection thresholds. However, they continue to suffer from relatively low sensitivity and figures of merit (FOMs). Herein we introduce the idea of sensitivity enhancement of LSPR sensors through engineering of the material dispersion function. Employing dispersion and shape engineering of chiral nanoparticles leads to remarkable refractive index sensitivities (1,091 nm RIU−1 at λ=921 nm) and FOMs (>2,800 RIU−1). A key feature is that the polarization-dependent extinction of the nanoparticles is now characterized by rich spectral features, including bipolar peaks and nulls, suitable for tracking refractive index changes. This sensing modality offers strong optical contrast even in the presence of highly absorbing media, an important consideration for use in complex biological media with limited transmission. The technique is sensitive to surface-specific binding events which we demonstrate through biotin–avidin surface coupling.
Type: | Article |
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Title: | Dispersion and shape engineered plasmonic nanosensors |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1038/ncomms11331 |
Publisher version: | http://dx.doi.org/10.1038/ncomms11331 |
Language: | English |
Additional information: | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
Keywords: | Physical sciences, Materials science, Nanotechnology, Optical physics |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office > Institute for Materials Discovery |
URI: | https://discovery.ucl.ac.uk/id/eprint/1489669 |
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