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An Assessment of the Risk of Bias in Randomized Controlled Trial Reports Published in Prosthodontic and Implant Dentistry Journals

Papageorgiou, SN; Kloukos, D; Petridis, H; Prosthod, C; Pandis, N; (2015) An Assessment of the Risk of Bias in Randomized Controlled Trial Reports Published in Prosthodontic and Implant Dentistry Journals. International Journal of Prosthodontics , 28 (6) pp. 586-593. 10.11607/ijp.4357.

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Abstract

Purpose: The objective of this study was to assess the risk of bias of randomized controlled trials (RCTs) published in prosthodontic and implantology journals. Materials and Methods: The last 30 issues of 9 journals in the field of prosthodontic and implant dentistry (Clinical Implant Dentistry and Related Research, Clinical Oral Implants Research, Implant Dentistry, International Journal of Oral & Maxillofacial Implants, International Journal of Periodontics and Restorative Dentistry, International Journal of Prosthodontics, Journal of Dentistry, Journal of Oral Rehabilitation and Journal of Prosthetic Dentistry) were hand-searched for RCTs. Risk of bias was assessed using the Cochrane Collaboration risk of bias tool and analyzed descriptively. Results: From the 3667 articles screened a total147 RCTs were identified and included. The number of published RCTs increased with time. The overall distribution of a high risk of bias assessment varied across the domains of the Cochrane risk of bias tool: 8% for random sequence generation, 18% for allocation concealment, 41% for masking, 47% for blinding of outcome assessment, 7% for incomplete outcome data, 12% for selective reporting, and 41% for other biases. Conclusions: The distribution of high risk of bias of RCTs published in the selected prosthodontic and implant dental journals varied among journals and ranged from 8%-47% and can be considered as substantial.

Type: Article
Title: An Assessment of the Risk of Bias in Randomized Controlled Trial Reports Published in Prosthodontic and Implant Dentistry Journals
DOI: 10.11607/ijp.4357
Publisher version: http://dx.doi.org/10.11607/ijp.4357
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Randomized controlled trial, implant dentistry, prosthodontics, risk of bias,Cochrane.
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Restorative Dental Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/1484038
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