Papageorgiou, SN;
Kloukos, D;
Petridis, H;
Prosthod, C;
Pandis, N;
(2015)
An Assessment of the Risk of Bias in Randomized Controlled Trial Reports Published in Prosthodontic and Implant Dentistry Journals.
The International Journal of Prosthodontics
, 28
(6)
pp. 586-593.
10.11607/ijp.4357.
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Abstract
Purpose: The objective of this study was to assess the risk of bias of randomized controlled trials (RCTs) published in prosthodontic and implantology journals. Materials and Methods: The last 30 issues of 9 journals in the field of prosthodontic and implant dentistry (Clinical Implant Dentistry and Related Research, Clinical Oral Implants Research, Implant Dentistry, International Journal of Oral & Maxillofacial Implants, International Journal of Periodontics and Restorative Dentistry, International Journal of Prosthodontics, Journal of Dentistry, Journal of Oral Rehabilitation and Journal of Prosthetic Dentistry) were hand-searched for RCTs. Risk of bias was assessed using the Cochrane Collaboration risk of bias tool and analyzed descriptively. Results: From the 3667 articles screened a total147 RCTs were identified and included. The number of published RCTs increased with time. The overall distribution of a high risk of bias assessment varied across the domains of the Cochrane risk of bias tool: 8% for random sequence generation, 18% for allocation concealment, 41% for masking, 47% for blinding of outcome assessment, 7% for incomplete outcome data, 12% for selective reporting, and 41% for other biases. Conclusions: The distribution of high risk of bias of RCTs published in the selected prosthodontic and implant dental journals varied among journals and ranged from 8%-47% and can be considered as substantial.
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