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Pilot randomised trial of a brief intervention for comorbid substance misuse in psychiatric in-patient settings

Graham, HL; Copello, A; Griffith, E; Freemantle, N; McCrone, P; Clarke, L; Walsh, K; ... Birchwood, M; + view all (2016) Pilot randomised trial of a brief intervention for comorbid substance misuse in psychiatric in-patient settings. Acta Psychiatrica Scandinavica , 133 (4) pp. 298-309. 10.1111/acps.12530. Green open access

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Abstract

OBJECTIVE: This proof of principle study evaluated the effectiveness and feasibility of a brief motivational intervention, delivered in mental health in-patient settings, to improve engagement in treatment for drug and alcohol misuse. METHOD: A randomised controlled trial using concealed randomisation, blind, independent assessment of outcome at 3 months. Participants were 59 new adult admissions, to six acute mental health hospital units in one UK mental health service, with schizophrenia related or bipolar disorder diagnoses, users of community mental health services and also misusing alcohol and/or drugs. Participants were randomised to Brief Integrated Motivational Intervention (BIMI) with Treatment As Usual (TAU), or TAU alone. The BIMI took place over a 2-week period and encouraged participants to explore substance use and its impact on mental health. RESULTS: Fifty-nine in-patients (BIMI n = 30; TAU n = 29) were randomised, the BIMI was associated with a 63% relative odds increase in the primary outcome engagement in treatment [OR 1.63 (95% CI 1.01-2.65; P = 0.047)], at 3 months. Qualitative interviews with staff and participants indicated that the BIMI was both feasible and acceptable. CONCLUSION: Mental health hospital admissions present an opportunity for brief motivational interventions focussed on substance misuse and can lead to improvements in engagement.

Type: Article
Title: Pilot randomised trial of a brief intervention for comorbid substance misuse in psychiatric in-patient settings
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1111/acps.12530
Publisher version: http://dx.doi.org/10.1111/acps.12530
Language: English
Additional information: This is the peer reviewed version of the following article: Graham, HL; Copello, A; Griffith, E; Freemantle, N; McCrone, P; Clarke, L; Walsh, K; (2016) Pilot randomised trial of a brief intervention for comorbid substance misuse in psychiatric in-patient settings. Acta Psychiatrica Scandinavica, 133 (4) pp. 298-309, which has been published in final form at: http://dx.doi.org/10.1111/acps.12530. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving (http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms).
Keywords: dual diagnosis, hospital admission, randomised controlled trial, schizophrenia, substance misuse
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > Comprehensive CTU at UCL
URI: https://discovery.ucl.ac.uk/id/eprint/1482132
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