TRUNCATE-TB: an innovative trial design for drug-sensitive tuberculosis

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TRUNCATE-TB: an innovative trial design for drug-sensitive tuberculosis

Papineni, P; Phillips, P; Lu, Q; Cheung, YB; Nunn, A; Paton, N; (2016) TRUNCATE-TB: an innovative trial design for drug-sensitive tuberculosis. International Journal of Infectious Diseases , 45 p. 404. 10.1016/j.ijid.2016.02.863. Green open access

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Abstract

Background: The number of potential regimens of drug treatment for TB is vast, meaning that evaluating each new treatment against a control in separate two-arm trials requires a huge amount of resources. There is, therefore, a need for innovative trial designs that can evaluate drug regimens simultaneously.

Type:	Article
Title:	TRUNCATE-TB: an innovative trial design for drug-sensitive tuberculosis
Open access status:	An open access version is available from UCL Discovery
DOI:	10.1016/j.ijid.2016.02.863
Publisher version:	http://dx.doi.org/10.1016/j.ijid.2016.02.863
Language:	English
Additional information:	Copyright © 2016 Published by Elsevier Ltd. This manuscript is made available under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International license (CC BY-NC-ND 4.0).
UCL classification:	UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Inst of Clinical Trials and Methodology > MRC Clinical Trials Unit at UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Global Health > Infection and Population Health
URI:	https://discovery.ucl.ac.uk/id/eprint/1477584

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