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Frailty predicts trajectories of quality of life over time among British community-dwelling older people

Kojima, G; Iliffe, S; Morris, RW; Taniguchi, Y; Kendrick, D; Skelton, DA; Masud, T; (2016) Frailty predicts trajectories of quality of life over time among British community-dwelling older people. Quality of Life Research 10.1007/s11136-015-1213-2. Green open access

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Abstract

PURPOSE: To investigate associations between baseline frailty status and subsequent changes in QOL over time among community-dwelling older people. METHODS: Among 363 community-dwelling older people ≥65 years, frailty was measured using Frailty Index (FI) constructed from 40 deficits at baseline. QOL was measured using Older People's Quality of Life Questionnaire (OPQOL) six times over 2.5 years. Two-level hierarchical linear models were employed to predict QOL changes over time according to baseline frailty. RESULTS: At baseline, mean age was 73.1 (range 65-90) and 62.0 % were women. Mean FI was 0.17 (range 0.00-0.66), and mean OPQOL was 130.80 (range 93-163). The hierarchical linear model adjusted for age, gender, ethnicity, education, and enrollment site predicted that those with higher FI at baseline have lower QOL than those with lower FI (regression coefficient = -47.64, p < 0.0001) and that QOL changes linearly over time with slopes ranging from 0.80 (FI = 0.00) to -1.15 (FI = 0.66) as the FI increases. A FI of 0.27 is the cutoff point at which improvements in QOL over time change to declines in QOL. CONCLUSIONS: Frailty was associated with lower QOL among British community-dwelling older people. While less frail participants had higher QOL at baseline and QOL improved over time, QOL of frailer participants was lower at baseline and declined.

Type: Article
Title: Frailty predicts trajectories of quality of life over time among British community-dwelling older people
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s11136-015-1213-2
Publisher version: http://dx.doi.org/10.1007/s11136-015-1213-2
Language: English
Additional information: © The Author(s) 2016. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Keywords: Community-dwelling older people, Frailty, Quality of life, Well-being
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/1475162
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